scholarly journals Blood markers in remote ischaemic conditioning for acute ischaemic stroke: data from the REmote ischaemic Conditioning After Stroke Trial

2020 ◽  
Author(s):  
Jason P. Appleton ◽  
Saoirse E. O’Sullivan ◽  
Amanda Hedstrom ◽  
Jane A. May ◽  
Richard Donnelly ◽  
...  
Keyword(s):  
Ischaemic Stroke ◽  
Acute Ischaemic Stroke ◽  
Remote Ischaemic Conditioning ◽  
Stroke Trial ◽  
Ischaemic Conditioning

scholarly journals The third international stroke trial (IST-3) of thrombolysis for acute ischaemic stroke

Trials ◽  
2008 ◽  
Vol 9 (1) ◽  
Author(s):  
Peter Sandercock ◽  
◽  
Richard Lindley ◽  
Joanna Wardlaw ◽  
Martin Dennis ◽  
...  
Keyword(s):  
Ischaemic Stroke ◽  
Acute Ischaemic Stroke ◽  
The Third ◽  
Stroke Trial

Thrombolysis with alteplase 3–4.5 hours after acute ischaemic stroke: trial reanalysis adjusted for baseline imbalances

2020 ◽  
Vol 59 (4) ◽  
pp. 623-624
Author(s):  
Anne Kathryn Watson ◽  
Amanda Young
Keyword(s):  
Ischaemic Stroke ◽  
Acute Ischaemic Stroke ◽  
Stroke Trial

scholarly journals No benefit of flat head positioning in early moderate–severe acute ischaemic stroke: a HeadPoST study subgroup analysis

2020 ◽  
Vol 5 (4) ◽  
pp. 406-409
Author(s):  
Alejandro M Brunser ◽  
Menglu Ouyang ◽  
Hisatomi Arima ◽  
Pablo M Lavados ◽  
Thompson Robinson ◽  
...  
Keyword(s):  
Ischaemic Stroke ◽  
Acute Ischaemic Stroke ◽  
Subgroup Analysis ◽  
Head Position ◽  
National Institutes Of Health ◽  
Baseline Risk ◽  
Serious Adverse Event ◽  
Head Positioning ◽  
Registration Number ◽  
Stroke Trial

BackgroundAlthough the Head Positioning in acute Stroke Trial (HeadPoST) showed no effect of the flat head position (FP; vs sitting up head position (SUP)) on functional outcome, we hypothesised that it could still offer benefits if commenced early in those with acute ischaemic stroke (AIS) of at least moderate severity.MethodsSubgroup analysis of HeadPoST in participants with National Institutes of Health Stroke Scale (NIHSS) scores ≥7, ≥10 and ≥14, randomised to FP or SUP <4.5 hours of AIS onset on functional outcomes defined by a shift in scores on the modified Rankin scale (mRS) and death/disability (mRS scores 3–6), and any cardiovascular serious adverse event. Logistic regression analyses were undertaken adjusted for study design and baseline risk factors.ResultsThere was no significant differential treatment effect in patient subgroups defined by increasing baseline NIHSS scores: adjusted OR and 95% CI for ordinal shift and binary (3–6) mRS scores: for NIHSS ≥7 (n=867) 0.92 (0.67 to 1.25) and 0.74 (0.52 to 1.04); NIHSS ≥ 10 (n=606) 0.80 (0.58 to 1.10) and 0.77 (0.49 to 1.19); NIHSS ≥14 (n=378) 0.82 (0.54 to 1.24) and 1.22 (0.69 to 2.14).ConclusionsEarly FP had no significant effect in patients with moderate–severe AIS.Trial registration numberNCT02162017.

scholarly journals Stroke severity, early recovery and outcome are each related with clinical classification of stroke: Data from the ‘Tinzaparin in Acute Ischaemic Stroke Trial’ (TAIST)

2007 ◽  
Vol 254 (1-2) ◽  
pp. 54-59 ◽  
Author(s):  
Nikola Sprigg ◽  
Laura J. Gray ◽  
Philip M.W. Bath ◽  
Ewa Lindenstrøm ◽  
Gudrun Boysen ◽  
...  
Keyword(s):  
Ischaemic Stroke ◽  
Acute Ischaemic Stroke ◽  
Stroke Severity ◽  
Clinical Classification ◽  
Early Recovery ◽  
Stroke Trial

scholarly journals Prediction of outcome in patients with suspected acute ischaemic stroke with CT perfusion and CT angiography: the Dutch acute stroke trial (DUST) study protocol

BMC Neurology ◽  
2014 ◽  
Vol 14 (1) ◽  
Author(s):  
Tom van Seeters ◽  
Geert Jan Biessels ◽  
Irene C van der Schaaf ◽  
Jan Willem Dankbaar ◽  
Alexander D Horsch ◽  
...  
Keyword(s):  
Ischaemic Stroke ◽  
Acute Stroke ◽  
Ct Angiography ◽  
Study Protocol ◽  
Acute Ischaemic Stroke ◽  
Ct Perfusion ◽  
Prediction Of Outcome ◽  
Stroke Trial
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