The Treatment of Angina Pectoris with a New Beta-receptor Blocking Agent (H 56/28)

2009 ◽  
Vol 182 (3) ◽  
pp. 285-291 ◽  
Author(s):  
Per Björntorp
CHEST Journal ◽  
1981 ◽  
Vol 80 (4) ◽  
pp. 425-430 ◽  
Author(s):  
William Shapiro ◽  
Janet Park ◽  
Robert DiBianco ◽  
Steven N. Singh ◽  
Richard J. Katz ◽  
...  

1973 ◽  
Vol 23 ◽  
pp. 35
Author(s):  
Yoichi Maruyama ◽  
Takafumi Ishihara ◽  
Ichiva Hiraki ◽  
Masayoshi Nozaki ◽  
Fumio Takenaka

1988 ◽  
Vol 22 (6) ◽  
pp. 484-485 ◽  
Author(s):  
Gopal Das ◽  
Janine C. Ferris

Beta-receptor blocking agents are commonly used to treat patients with heart disease, and generalized seizures due to therapy with these agents are rare. All reported cases of seizures due to beta blocking agents have occurred only in those subjects who ingested large doses of the drugs. We observed generalized convulsions in a patient who was receiving therapeutic doses of an ultrashort-acting beta-blocking agent (esmolol hydrochloride) intravenously. A literature survey and possible mechanisms by which these agents induce seizures are presented.


1976 ◽  
Vol 4 (6) ◽  
pp. 410-417 ◽  
Author(s):  
A K Agarwal ◽  
R C Ahuja ◽  
M Chandra ◽  
N N Gupta ◽  
M Hasan

A double-blind placebo controlled study of angina pectoris with Penbutolol was undertaken in parallel groups in fifty-two patients. The duration of the study was six weeks. The dosage range for Penbutolol was 8 mg to 50 mg per day. Six patients were dropped from the analysis. Seventeen patients (81%) in the Penbutolol series exhibited a 50% reduction in anginal attacks, NTG consumption and subjective improvement. Significant reduction in nitrite intake was observed. Effort tolerance was improved significantly in those receiving penbutolol. Penbutolol was well-tolerated.


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