Results of Antihypertensive Treatment Trials in the Elderly

2002 ◽  
Vol 11 (1) ◽  
pp. 41-48 ◽  
Author(s):  
Gastone Leonetti ◽  
Alberto Zanchetti
Keyword(s):  
Antihypertensive Treatment ◽  
The Elderly ◽  
Treatment Trials

Antihypertensive treatment with a dual-acting beta-blocker in the elderly

1993 ◽  
Vol 11 (Supplement 4) ◽  
pp. S29???S36 ◽  
Author(s):  
Jan N. Lessem ◽  
Michael A. Weber
Keyword(s):  
Beta Blocker ◽  
Antihypertensive Treatment ◽  
The Elderly

JAPANESE TRIAL ON THE EFFICACY OF ANTIHYPERTENSIVE TREATMENT IN THE ELDERLY II (JATE II)

2004 ◽  
Vol 22 (Suppl. 1) ◽  
pp. S149
Author(s):  
Y Kawano ◽  
S Takishita ◽  
H Matsuoka ◽  
T Mannami ◽  
T Omae
Keyword(s):  
Antihypertensive Treatment ◽  
The Elderly

scholarly journals Antihypertensive Treatment in the Elderly and Very Elderly: Always “the Lower, the Better?”

2012 ◽  
Vol 2012 ◽  
pp. 1-4 ◽  
Author(s):  
Alberto Mazza ◽  
Emilio Ramazzina ◽  
Stefano Cuppini ◽  
Michela Armigliato ◽  
Laura Schiavon ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Clinical Trials ◽  
Antihypertensive Treatment ◽  
Antihypertensive Drugs ◽  
The Elderly ◽  
Organ Damage ◽  
Very Elderly ◽  
Age Dependent ◽  
Prolongation Of Life ◽  
Per Se

Arterial hypertension (HT) is age dependent and, with the prolongation of life expectancy, affects more and more elderly people. In the elderly, HT is a risk factor for organ damage and cardiovascular (CV) events. Both pharmacologic and nonpharmacologic reduction of blood pressure (BP) is associated with a corresponding decrease in systolic-diastolic or isolated systolic HT. Clinical trials have shown that BP lowering is associated with a decrease in stroke and other CV events. Therefore, BP reductionper seappears more important than a particular class of antihypertensive drugs. The benefit of antihypertensive treatment has been confirmed up to the age of 80 years, remaining unclear in the octogenarians. The benefit in lowering diastolic BP between 80 and 90 mmHg is well established, while that of lowering systolic BP below 140 mmHg requires further confirmations.

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