scholarly journals A minimally invasive metabolic test with intramuscular injection of halothane 5 and 6 vol% to detect probands at risk for malignant hyperthermia

Anaesthesia ◽  
2007 ◽  
Vol 62 (9) ◽  
pp. 882-887 ◽  
Author(s):  
F. Schuster ◽  
A. Gardill ◽  
T. Metterlein ◽  
P. Kranke ◽  
N. Roewer ◽  
...  
2013 ◽  
Vol 2013 ◽  
pp. 1-4 ◽  
Author(s):  
Frank Schuster ◽  
Stephan Johannsen ◽  
Norbert Roewer

Malignant hyperthermia is a rare but life-threatening complication of general anesthesia in predisposed patients usually triggered by potent inhalation anesthetics and/or the depolarizing muscle relaxant succinylcholine. The authors present a case of delayed sevoflurane-induced malignant hyperthermia in a 21-year-old male patient that was sufficiently treated by discontinuation of trigger agent application and dantrolene infusion. After surviving an MH episode diagnostic procedures are indicated to increase patient safety. In the presented case, the use of a novel minimal-invasive metabolic test with intramuscular injection of halothane and caffeine successfully confirmed MH susceptibility and hence might be an alternative for invasive in vitro contracture testing in selected cases.


Author(s):  
Y. S. Alizade ◽  
L. B. Rudin

The potential predictive possibilities of minimally invasive prenosological diagnosis of voice disorders on the basis of combined Geno - and phenotyping of persons at risk of diseases of the vocal folds of professional origin.


The Lancet ◽  
2002 ◽  
Vol 359 (9317) ◽  
pp. 1579-1580 ◽  
Author(s):  
Martin Anetseder ◽  
Martin Hager ◽  
Clemens R Müller ◽  
Norbert Roewer

1998 ◽  
Vol 12 (2) ◽  
Author(s):  
Yuka Shimonagano ◽  
Yoshitami Kadota ◽  
Koichi Kawasaki ◽  
Takashi Gushiken ◽  
Nozomu Yoshimura

2008 ◽  
Vol 107 (3) ◽  
pp. 909-914 ◽  
Author(s):  
Frank Schuster ◽  
Thomas Metterlein ◽  
Sabrina Negele ◽  
Peter Kranke ◽  
Ralf M. Muellenbach ◽  
...  

The Lancet ◽  
2003 ◽  
Vol 362 (9382) ◽  
pp. 494 ◽  
Author(s):  
Martin Anetseder ◽  
Martin Hager ◽  
Clemens Müller-Reible ◽  
Norbert Roewer

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