A first prospective randomized controlled trial to decrease bacterial load using cold atmospheric argon plasma on chronic wounds in patients

2010 ◽  
Vol 163 (1) ◽  
pp. 78-82 ◽  
Author(s):  
G. Isbary ◽  
G. Morfill ◽  
H.U. Schmidt ◽  
M. Georgi ◽  
K. Ramrath ◽  
...  
Keyword(s):  
Randomized Controlled Trial ◽  
Chronic Wounds ◽  
Controlled Trial ◽  
Bacterial Load ◽  
Argon Plasma ◽  
Randomized Controlled ◽  
Prospective Randomized Controlled Trial ◽  
Atmospheric Argon

scholarly journals A prospective, randomized, controlled, crossover study comparing three multilayered foam dressings for the management of chronic wounds

2021 ◽  
Vol 10 (6) ◽  
pp. 481-493
Author(s):  
Oscar M Alvarez ◽  
Mark S Granick ◽  
Alexander Reyzelman ◽  
Thomas Serena
Keyword(s):  
Randomized Controlled Trial ◽  
Crossover Study ◽  
Chronic Wounds ◽  
Controlled Trial ◽  
Crossover Design ◽  
Size Reduction ◽  
Randomized Controlled ◽  
End Point ◽  
Prospective Randomized Controlled Trial ◽  
Dressing Change

Aim: Compare foam dressings – Mepilex Border Flex (MxBF), Allevyn Life (AL) and Optifoam Gentle EX (OGEX) – in treatment of chronic wounds. Materials & methods: Prospective, randomized, controlled trial (crossover design). Subjects received one dressing for 2 weeks, then comparator dressing for following 2 weeks. Wound/periwound characteristics evaluated weekly at dressing change. Primary end point: dressing durability (incidence of exudate strikethrough). Results: Higher incidence of intact dressings (no strikethrough) at Day 7 (Week 1) with MxBF (6/17; 35.3%) compared with AL (1/18; 5.6%), and with MxBF (7/16; 43.8%) compared with OGEX (2/16; 12.5%; p < 0.05). No significant differences between groups regarding wound size reduction. Conclusion: MxBF had statistically greater durability than AL/OGEX during first critical week of treatment.

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