scholarly journals Clinical Practice Guidelines for the management of atypical Haemolytic Uraemic Syndrome in the United Kingdom

2010 ◽  
Vol 148 (1) ◽  
pp. 37-47 ◽  
Author(s):  
C. Mark Taylor ◽  
Sam Machin ◽  
Stephen J. Wigmore ◽  
Tim H. J. Goodship ◽  
2021 ◽  
Author(s):  
Charlotte Koldeweij ◽  
Jonathan Clarke ◽  
Carmen Rodriguez Gonzalvez ◽  
Joppe Nijman ◽  
Ruchi Sinha ◽  
...  

Background: Clinical practice guidelines (CPGs) aim to standardize clinical care. Increasingly, hospitals rely on locally produced guidelines alongside national guidance. This study examines variation between national and local CPGs, using the example of acute paediatric asthma guidance from the United Kingdom and the Netherlands. Methods: Fifteen British and Dutch local CPGs were collected with the matching national guidance for the management of acute asthma in children under 18 years old. The drug sequences, routes and methods of administration recommended for patients with severe asthma and the tone of recommendation across both types of CPGs were schematically represented. Deviations from national guidance were measured. Variation in recommended doses of intravenous salbutamol was examined. Results: British and Dutch national CPGs differed in the recommended drug choices, sequences, routes and methods of administration for severe asthma. Dutch national guidance was more rigidly defined. Local British CPGs diverged from national guidance for 23% of their recommended interventions compared to 8% for Dutch local CPGs. Five British local guidelines and two Dutch local guidelines differed from national guidance for multiple treatment steps. Variation in second-line recommendations was greater than for first-line recommendations across local CPGs from both countries. Recommended starting doses for salbutamol infusions varied by more than tenfold. Conclusions: Local CPGs for the management of severe acute paediatric asthma featured substantial variation and frequently diverged from national guidance. Although limited to one condition, this study suggests that unmeasured variation across local CPGs may contribute to variation of care more broadly, with possible effects on healthcare quality.


2001 ◽  
Vol 24 (1) ◽  
pp. 192 ◽  
Author(s):  
Barbara Liebert ◽  
Michael Parle ◽  
Kate White ◽  
Alan Rodger

The unmet needs of women with breast cancer have been extensively documented. In the United Kingdom, theintroduction of the specialist breast nurse (SBN) role has been one strategy to improve the psychological wellbeing ofwomen. This paper describes a SBN model of care and clinical pathway for Australian treatment settings, developedfrom systematic reviews of research and clinical practice guidelines for the treatment and psychosocial care of womenwith breast cancer. The model acknowledges the SBN as an integral member of the multi-disciplinary team with akey role to meet the emotional and informational needs of women diagnosed with breast cancer from the time ofdiagnosis through to follow up after treatment.Key words: breast cancer, specialist breast nurse, evidence-based, clinical practice guidelines, clinical pathway,psychosocial support


2020 ◽  
Vol 5 (4) ◽  
pp. 1006-1010
Author(s):  
Jennifer Raminick ◽  
Hema Desai

Purpose Infants hospitalized for an acute respiratory illness often require the use of noninvasive respiratory support during the initial stage to improve their breathing. High flow oxygen therapy (HFOT) is becoming a more popular means of noninvasive respiratory support, often used to treat respiratory syncytial virus/bronchiolitis. These infants present with tachypnea and coughing, resulting in difficulties in coordinating sucking and swallowing. However, they are often allowed to feed orally despite having high respiratory rate, increased work of breathing and on HFOT, placing them at risk for aspiration. Feeding therapists who work with these infants have raised concerns that HFOT creates an additional risk factor for swallowing dysfunction, especially with infants who have compromised airways or other comorbidities. There is emerging literature concluding changes in pharyngeal pressures with HFOT, as well as aspiration in preterm neonates who are on nasal continuous positive airway pressure. However, there is no existing research exploring the effect of HFOT on swallowing in infants with acute respiratory illness. This discussion will present findings from literature on HFOT, oral feeding in the acutely ill infant population, and present clinical practice guidelines for safe feeding during critical care admission for acute respiratory illness. Conclusion Guidelines for safety of oral feeds for infants with acute respiratory illness on HFOT do not exist. However, providers and parents continue to want to provide oral feeds despite clinical signs of respiratory distress and coughing. To address this challenge, we initiated a process change to use clinical bedside evaluation and a “cross-systems approach” to provide recommendations for safer oral feeds while on HFOT as the infant is recovering from illness. Use of standardized feeding evaluation and protocol have improved consistency of practice within our department. However, further research is still necessary to develop clinical practice guidelines for safe oral feeding for infants on HFOT.


Sign in / Sign up

Export Citation Format

Share Document