Heme oxygenase-1 improves the survival of discordant cardiac xenograft through its anti-inflammatory and anti-apoptotic effects

2007 ◽  
Vol 11 (8) ◽  
pp. 850-859 ◽  
Author(s):  
Xia Zhen-Wei ◽  
Sun Jian-Le ◽  
Qi Qi ◽  
Zhong Wen-Wei ◽  
Zhang Xue-Hong ◽  
...  
Keyword(s):  
Heme Oxygenase ◽  
Heme Oxygenase 1 ◽  
Anti Inflammatory ◽  
Apoptotic Effects

Heme oxygenase-1 mediates the anti-inflammatory effect of mushroom Phellinus linteus in LPS-stimulated RAW264.7 macrophages

2006 ◽  
Vol 106 (3) ◽  
pp. 364-371 ◽  
Author(s):  
Byung-Chul Kim ◽  
Joung-Woo Choi ◽  
Hye-Young Hong ◽  
Sin-Ae Lee ◽  
Suntaek Hong ◽  
...  
Keyword(s):  
Heme Oxygenase ◽  
Heme Oxygenase 1 ◽  
Phellinus Linteus ◽  
Raw264.7 Macrophages ◽  
Anti Inflammatory ◽  
Inflammatory Effect

scholarly journals Role of nuclear factor-κ B and heme oxygenase-1 in the mechanism of action of an anti-inflammatory chalcone derivative in RAW 264.7 cells

2004 ◽  
Vol 142 (7) ◽  
pp. 1191-1199 ◽  
Author(s):  
María José Alcaraz ◽  
Ana María Vicente ◽  
Amparo Araico ◽  
José N Dominguez ◽  
María Carmen Terencio ◽  
...  
Keyword(s):  
Heme Oxygenase ◽  
Mechanism Of Action ◽  
Raw 264.7 Cells ◽  
Heme Oxygenase 1 ◽  
Raw 264.7 ◽  
Nuclear Factor ◽  
Chalcone Derivative ◽  
Anti Inflammatory ◽  
Nuclear Factor Κ B

scholarly journals Shepherd’s Purse Polyphenols Exert Its Anti-Inflammatory and Antioxidative Effects Associated with Suppressing MAPK and NF-κB Pathways and Heme Oxygenase-1 Activation

2019 ◽  
Vol 2019 ◽  
pp. 1-14 ◽  
Author(s):  
Jinming Peng ◽  
Tianyong Hu ◽  
Jin Li ◽  
Jing Du ◽  
Kerui Zhu ◽  
...  
Keyword(s):  
Heme Oxygenase ◽  
Chemical Constituents ◽  
Chemical Compounds ◽  
Heme Oxygenase 1 ◽  
Mice Model ◽  
Traditional Herbal Medicine ◽  
Raw 264.7 Macrophages ◽  
Antioxidative Effects ◽  
Anti Inflammatory

Shepherd’s purse (Capsella bursa-pastoris (L.) Medik.), a wild herb as a traditional herbal medicine, has been proved with multiple healthy benefits. In this study, the chemical constituents of shepherd’s purse were identified by UPLC-QTOF-MS/MS. The antioxidative and anti-inflammatory potential of shepherd’s purse extract (SPE) were also investigated applying lipopolysaccharide- (LPS-) induced inflammation in RAW 264.7 macrophages and a carrageenan-induced mice paw edema model. Twenty-four chemical compounds were identified mainly including phenolic acids and flavonoids. The data also indicated SPE inhibited the productions of NO, PGE2, TNF-α, and IL-6 stimulated with LPS. In addition, SPE inhibited the increase of reactive oxygen species (ROS) and upregulated the expression of heme oxygenase-1 (HO-1). We further found that SPE inhibited the phosphorylation of P38 MAPK and activation of NF-κB. In vivo mice model also indicated that SPE showed strong antioxidative and anti-inflammatory activity.

scholarly journals Anti-inflammatory effects ofSaururus chinensisaerial parts in murine macrophages via induction of heme oxygenase-1

2015 ◽  
Vol 241 (4) ◽  
pp. 396-408 ◽  
Author(s):  
Xue Meng ◽  
Inhye Kim ◽  
Yong Joon Jeong ◽  
Young Mi Cho ◽  
Se Chan Kang
Keyword(s):  
Heme Oxygenase ◽  
Heme Oxygenase 1 ◽  
Murine Macrophages ◽  
Anti Inflammatory
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