Continuous subcutaneous insulin infusion benefits quality of life in preschool-age children with type 1 diabetes mellitus

2007 ◽  
Vol 8 (6) ◽  
pp. 377-383 ◽  
Author(s):  
Lisa Opipari-Arrigan ◽  
Emily M Fredericks ◽  
Nugget Burkhart ◽  
Linda Dale ◽  
Mary Hodge ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Diabetes Mellitus ◽  
Type 1 Diabetes ◽  
Continuous Subcutaneous Insulin Infusion ◽  
Insulin Infusion ◽  
Preschool Age ◽  
Subcutaneous Insulin ◽  
Preschool Age Children

Impact of Intensive Therapy With Continuous Subcutaneous Insulin Infusion on Quality of Life in Patients With Type 1 Diabetes

2010 ◽  
Vol 15 (1) ◽  
pp. 1-19 ◽  
Author(s):  
María Teresa Anarte Ortiz ◽  
Francisco Félix Caballero Díaz ◽  
Alberto Machado Romero ◽  
María Soledad Ruiz de Adana Navas ◽  
Marta Domínguez-López ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Type 1 Diabetes ◽  
Continuous Subcutaneous Insulin Infusion ◽  
Insulin Infusion ◽  
Intensive Therapy ◽  
Subcutaneous Insulin

scholarly journals Use of continuous subcutaneous insulin infusion by a portable insulin pump during pregnancy in women with type 1 diabetes mellitus

2006 ◽  
Vol 63 (7) ◽  
pp. 648-651 ◽  
Author(s):  
Svetlana Zoric ◽  
Dragan Micic ◽  
Aleksandra Kendereski ◽  
Mirjana Sumarac-Dumanovic ◽  
Goran Cvijovic ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Type 1 Diabetes ◽  
Type 1 Diabetes Mellitus ◽  
Pregnancy Outcome ◽  
Continuous Subcutaneous Insulin Infusion ◽  
Insulin Infusion ◽  
Insulin Pump ◽  
Subcutaneous Insulin

Background/aim: Diabetes mellitus is associated with an increased risk for neonatal morbidity and mortality. One of the most important goals in treating pregnancies complicated with diabetes is keeping glucose level within the normal range, especially in the first trimester. A portable insulin pump for continuous subcutaneous insulin infusion (CSII) represents the best form of therapy for patients with type 1 diabetes mellitus during pregnancy. The aim of our study was to evaluate the effects of therapy with a portable insulin pump for continuous subcutaneous insulin infusion during the first trimester of pregnancy on the quality of glycoregulation and pregnancy outcome in women with type 1 diabetes mellitus. Methods. A total of 17 newly diagnosed pregnant women with type 1 diabetes mellitus were treated with CSII therapy for three months. The parameters of glycoregulation (hemoglobin A, glycosylated - HbA1c, mean blood glucose value in daily profiles - MBG, daily requirement for insulin - IJ/kg BM), lipid levels, blood pressure and renal function were estimated before and after the therapy. These parameters were correlated with parameters of pregnancy outcome: fetal weight, APGAR score, duration of pregnancy. Results. There was a significant improvement in HbA1c (8.94?1.62 vs. 6.90?1.22 %, p < 0.05), MBG (9.23?2.22 vs. 6.41?1.72 mmol/l, p < 0.01), and daily requirement for insulin (0.66?0.22 vs. 0.55?0.13 IJ/kg BM, p < 0.05) during the CSII therapy. There were significant correlations between fetal weight and HbA1c (r = -0.60, p < 0.05), triglyceride levels (r = ?0.63, p < 0.01), and the number of pregnancies (r = ?0.62, p < 0.01), as well as between APGAR score and MBG (r = ?0.52, p < 0.05) and cholesterol levels (r = ?0.65, p < 0,01) before a portable insulin pump was applicated. Conclusions. There was a significant improvement in the quality of glycoregulation during CSII therapy in the pregnant women with type 1 diabetes mellitus. The quality of glycoregulation in the moment of conception was the important factor for pregnancy outcome.

scholarly journals BENEFITS OF CONTINUOUS SUBCUTANEOUS INSULIN INFUSION ON QUALITY OF LIFE

2012 ◽  
Vol 29 (1) ◽  
pp. 48-52 ◽  
Author(s):  
Andrea Lukács ◽  
Emőke Kiss-Tóth ◽  
Beatrix Varga ◽  
Andrea Soós ◽  
Peter Takác ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Type 1 Diabetes ◽  
Physical Fitness ◽  
Metabolic Control ◽  
Continuous Subcutaneous Insulin Infusion ◽  
Insulin Infusion ◽  
Anthropometric Measurement ◽  
Subcutaneous Insulin

Purpose: The aim of this study was to compare the general health-related quality of life (HRQoL), the metabolic control (HbA1c), the anthropometric measurement, and the cardiorespiratory fitness (expressed by VO2max) in youths with type 1 diabetes treated with continuous subcutaneous insulin infusion (CSII) to those receiving multiple daily injections (MDI). We looked for factors influencing the HRQoL and metabolic control.Methods: A total of 239 patients treated with CSII (51 girls and 53 boys) or MDI (64 girls and 71 boys) between ages 8 and 18 years were assessed with the Pediatric Quality of Life Inventory, Generic Core Scales, and Diabetes Module. VO2max was evaluated using the 20-meter shuttle run test.Results: CSII group had significantly better HRQoL according to both child self-report and parent proxy-report. Youths with CSII reported better physical, emotional, and school-related functioning, and had less diabetes-related fear and symptoms than the MDI group. There were no significant differences in body mass index z-scores, insulin doses, HbA1c, and VO2max between the groups. HRQoL was predicted by the CSII therapy (β = −0.220; p = .000) and the VO2max (β = 0.386; p = .000), other clinical and anthropometric parameters had no effect; the HbA1c was predicted only by VO2max (β = −0.353; p = .000).Conclusions: Diabetic youths treated with CSII therapy have better HRQoL than those treated with MDI. There are no differences between the investigated groups in anthropometric data, glycated hemoglobin, and physical fitness. Moreover, good physical fitness has an important role in achieving better metabolic control and HRQoL, which underlines the importance of regular aerobic exercise in the treatment and care of type 1 diabetes in childhood.

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