The effects of sevoflurane on cerebral blood flow autoregulation and flow-metabolism coupling during cardiopulmonary bypass

2010 ◽  
Vol 55 (1) ◽  
pp. 118-123 ◽  
Author(s):  
B. REINSFELT ◽  
A. WESTERLIND ◽  
S.-E. RICKSTEN
Keyword(s):  
Blood Flow ◽  
Cerebral Blood Flow ◽  
Cardiopulmonary Bypass ◽  
Cerebral Blood Flow Autoregulation

THE EFFECT OF AGE ON CEREBRAL BLOOD FLOW AUTOREGULATION DURING HYPOTHERMIC CARDIOPULMONARY BYPASS

1987 ◽  
Vol 67 (3) ◽  
pp. A10-A10 ◽  
Author(s):  
F. G. Brusino ◽  
J. G. Reves ◽  
D. S. Prough ◽  
D. A. Stump ◽  
N. D. Croughwell
Keyword(s):  
Blood Flow ◽  
Cerebral Blood Flow ◽  
Cardiopulmonary Bypass ◽  
Hypothermic Cardiopulmonary Bypass ◽  
Cerebral Blood Flow Autoregulation ◽  
Effect Of Age

scholarly journals Multiple Factors Involved in the Pathogenesis of White Matter Lesions

2017 ◽  
Vol 2017 ◽  
pp. 1-9 ◽  
Author(s):  
Jing Lin ◽  
Dilong Wang ◽  
Linfang Lan ◽  
Yuhua Fan
Keyword(s):  
Blood Flow ◽  
Cerebral Blood Flow ◽  
White Matter ◽  
Genetic Factors ◽  
Subsequent Development ◽  
White Matter Lesions ◽  
Blood Brain Barrier Disruption ◽  
Fluid Attenuated Inversion Recovery ◽  
Cerebral Blood Flow Autoregulation ◽  
Brain Barrier Disruption

White matter lesions (WMLs), also known as leukoaraiosis (LA) or white matter hyperintensities (WMHs), are characterized mainly by hyperintensities on T2-weighted or fluid-attenuated inversion recovery (FLAIR) images. With the aging of the population and the development of imaging technology, the morbidity and diagnostic rates of WMLs are increasing annually. WMLs are not a benign process. They clinically manifest as cognitive decline and the subsequent development of dementia. Although WMLs are important, their pathogenesis is still unclear. This review elaborates on the advances in the understanding of the pathogenesis of WMLs, focusing on anatomy, cerebral blood flow autoregulation, venous collagenosis, blood brain barrier disruption, and genetic factors. In particular, the attribution of WMLs to chronic ischemia secondary to venous collagenosis and cerebral blood flow autoregulation disruption seems reasonable. With the development of gene technology, the effect of genetic factors on the pathogenesis of WMLs is gaining gradual attention.

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