Comparison of three current staging systems for hepatocellular carcinoma: Japan integrated staging score, new Barcelona Clinic Liver Cancer staging classification, and Tokyo score

2008 ◽  
Vol 23 (3) ◽  
pp. 445-452 ◽  
Author(s):  
Hobyung Chung ◽  
Masatoshi Kudo ◽  
Shunsuke Takahashi ◽  
Satoru Hagiwara ◽  
Yasuhiro Sakaguchi ◽  
...  
Keyword(s):  
Hepatocellular Carcinoma ◽  
Liver Cancer ◽  
Cancer Staging ◽  
Barcelona Clinic Liver Cancer ◽  
Staging Systems ◽  
Staging Classification

Validity of the Barcelona Clinic Liver Cancer and Hong Kong Liver Cancer staging systems for hepatocellular carcinoma in Singapore

2017 ◽  
Vol 24 (3) ◽  
pp. 143-152 ◽  
Author(s):  
Li Kim E. Selby ◽  
Rosanna X. Y. Tay ◽  
Winston W. L. Woon ◽  
Jee Keem Low ◽  
Wang Bei ◽  
...  
Keyword(s):  
Hepatocellular Carcinoma ◽  
Hong Kong ◽  
Liver Cancer ◽  
Cancer Staging ◽  
Barcelona Clinic Liver Cancer ◽  
Staging Systems

Surgical Treatment for Hepatocellular Carcinoma in the Era of Multiple Staging and Algorithm

2018 ◽  
Author(s):  
Suguru Yamashita ◽  
Katharina Joechle ◽  
Jean-Nicolas Vauthey
Keyword(s):  
Hepatocellular Carcinoma ◽  
Liver Cancer ◽  
Treatment Algorithm ◽  
Staging System ◽  
Cancer Staging ◽  
Barcelona Clinic Liver Cancer ◽  
Term Survival ◽  
American Joint Committee ◽  
Staging Systems ◽  
Surgical Treatments

A plethora of staging systems for hepatocellular carcinoma (HCC) has existed, as the management for HCC is made complex by the interplay of tumor characteristics and the health and underlying functions of both the patient and the liver. The majority of patients with HCC have nonsurgical HCC. The Barcelona Clinic Liver Cancer (BCLC) classification has been regarded as the optimal staging system and treatment algorithm for HCC. However, even in patients with intermediate or advanced stage in BCLC classification, who had not been originally recommended to undergo surgery, some could benefit in terms of long-term survival by surgical treatments. An expert panel on HCC has stated that the American Joint Committee on Cancer staging system, whose predictive power on the outcome have been improved by continuous amendments, should be applied for patients undergoing surgery. Herein, we review the recent staging system focusing on patients with HCC undergoing surgery.   This review contains 5 figures, 3 tables and 34 references Key Words: American Joint Committee on Cancer, Barcelona Clinic Liver Cancer, hepatic resection, hepatocellular carcinoma, orthotopic liver transplantation

Surgical Treatment for Hepatocellular Carcinoma in the Era of Multiple Staging and Algorithm

2018 ◽  
Author(s):  
Suguru Yamashita ◽  
Katharina Joechle ◽  
Jean-Nicolas Vauthey
Keyword(s):  
Hepatocellular Carcinoma ◽  
Liver Cancer ◽  
Treatment Algorithm ◽  
Staging System ◽  
Cancer Staging ◽  
Barcelona Clinic Liver Cancer ◽  
Term Survival ◽  
American Joint Committee ◽  
Staging Systems ◽  
Surgical Treatments

A plethora of staging systems for hepatocellular carcinoma (HCC) has existed, as the management for HCC is made complex by the interplay of tumor characteristics and the health and underlying functions of both the patient and the liver. The majority of patients with HCC have nonsurgical HCC. The Barcelona Clinic Liver Cancer (BCLC) classification has been regarded as the optimal staging system and treatment algorithm for HCC. However, even in patients with intermediate or advanced stage in BCLC classification, who had not been originally recommended to undergo surgery, some could benefit in terms of long-term survival by surgical treatments. An expert panel on HCC has stated that the American Joint Committee on Cancer staging system, whose predictive power on the outcome have been improved by continuous amendments, should be applied for patients undergoing surgery. Herein, we review the recent staging system focusing on patients with HCC undergoing surgery.   This review contains 5 figures, 3 tables and 34 references Key Words: American Joint Committee on Cancer, Barcelona Clinic Liver Cancer, hepatic resection, hepatocellular carcinoma, orthotopic liver transplantation

scholarly journals BIOCHEMICAL NUTRITIONAL PROFILE OF LIVER CIRRHOSIS PATIENTS WITH HEPATOCELLULAR CARCINOMA

2014 ◽  
Vol 51 (1) ◽  
pp. 10-15 ◽  
Author(s):  
Gabriela Zanatta PORT ◽  
Kalinca OLIVEIRA ◽  
Jonathan SOLDERA ◽  
Cristiane Valle TOVO
Keyword(s):  
Hepatocellular Carcinoma ◽  
Liver Cirrhosis ◽  
Liver Cancer ◽  
Metabolic Disorders ◽  
Nutritional Assessment ◽  
Cancer Staging ◽  
Barcelona Clinic Liver Cancer ◽  
Nutritional Profile ◽  
Methods Analytical ◽  
Transversal Study

Context Liver cirrhosis patients with hepatocellular carcinoma present nutritional alterations and metabolic disorders that negatively impact the prognosis. Objective The objective is to identify alterations in the metabolism of macro and micronutrients among liver cirrhosis patients with and without hepatocellular carcinoma and their relation to the Child-Turcote-Pugh score and Barcelona Clinic Liver Cancer staging. Methods Analytical transversal study, with 31 hepatocellular carcinoma patients and 48 liver cirrhosis patients. Laboratorial exams were carried out. The existence of an association between the biochemical parameters and the disease severity as well as the presence of hepatocellular carcinoma was assessed. Results The metabolic-nutritional profile of liver cirrhosis patients caused by the hepatitis C virus and hepatocellular carcinoma showed alterations, specifically the lipid (total cholesterol, HDL and triglycerides), protein (albumin, creatinine and uric acid), iron (transferrin, iron and ferritin saturation), hematocrit and hemoglobin, zinc and B12 vitamin profiles. There is a relation between nutritional biochemical markers and the Child-Turcote-Pugh, as well as Barcelona Clinic Liver Cancer staging. Conclusions Considering the existence of alterations in the metabolism of nutrients in liver cirrhosis patients with and without hepatocellular carcinoma, and also that conventional nutritional assessment methods present limitations for this population, the biochemical laboratorial exams are valid to complement the diagnosis of the nutritional state in a quick and practical manner.

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