Genetic differentiation of the bronze featherback Notopterus notopterus between Mekong River and Tonle Sap Lake populations by mitochondrial DNA analysis

2006 ◽  
Vol 72 (4) ◽  
pp. 750-754 ◽  
Author(s):  
Akira P TAKAGI ◽  
Satoshi ISHIKAWA ◽  
Thuok NAO ◽  
Sitha HORT ◽  
Masanori NAKATANI ◽  
...  
2015 ◽  
Vol 51 (12) ◽  
pp. 1221-1232 ◽  
Author(s):  
L. A. Skurikhina ◽  
A. G. Oleinik ◽  
A. D. Kukhlevsky ◽  
N. E. Kovpak ◽  
D. S. Sendek ◽  
...  

2006 ◽  
Vol 72 (1) ◽  
pp. 20-27 ◽  
Author(s):  
Alberto Teodorico CORREIA ◽  
Rui FARIA ◽  
Paulo ALEXANDRINO ◽  
Carlos ANTUNES ◽  
Eduardo Jose ISIDRO ◽  
...  

2020 ◽  
Vol 70 (12) ◽  
pp. 4244-4247

Leber hereditary optical neuropathy (LHON) is part of the class of optic neuropathies in which the mitochondrial function is impaired and is characterized by a painless, subacute, bilateral decrease of the central vision. We shall present the case of two brothers AM aged 31 and AT aged 40 who were diagnosed with LHON and whom we initiated treatment with idebenone 900 mg / day with monitoring at one month and 6 months. The mitochondrial DNA analysis demonstrated the existence of mutations 11778G>A for the mtND4 gene in both patients. Idebenone is a synthetic benzoquinone, analogue of ubiquinone. We found a slight but significant improvement in the visual field in patient AM at one month of treatment. We have not found another case in the literature with an improvement in vision so fast after this treatment, and this has led us to write this article. Keywords: Leber hereditary optical neuropathy (LHON), idebenone, mutations 11778G>A, mtND4 gene


PLoS ONE ◽  
2007 ◽  
Vol 2 (10) ◽  
pp. e1012 ◽  
Author(s):  
Saeid Naderi ◽  
Hamid-Reza Rezaei ◽  
Pierre Taberlet ◽  
Stéphanie Zundel ◽  
Seyed-Abbas Rafat ◽  
...  

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