Urgent liver transplantation for acute liver failure due to parvovirus B19 infection complicated by primary Epstein?Barr virus and cytomegalovirus infections and aplastic anaemia

2007 ◽  
Vol 37 (3) ◽  
pp. 192-195 ◽  
Author(s):  
K. So ◽  
G. Macquillan ◽  
G. Garas ◽  
L. Delriviere ◽  
A. Mitchell ◽  
...  
2013 ◽  
Vol 108 ◽  
pp. S320-S321
Author(s):  
Joshua Peck ◽  
Lana Alghothani ◽  
Steven Campbell ◽  
John Davis ◽  
James Hanje

2020 ◽  
Vol 13 (3) ◽  
pp. 1232-1238
Author(s):  
Mark Forsberg ◽  
Mark Galan ◽  
Joshua Kra

Infectious mononucleosis is a largely benign disease process that occurs secondary to infection with the Epstein-Barr virus. However, it can also present with more serious complications, including auto-immune hemolytic anemia and acute liver failure. Hereditary hemochromatosis is a genetic disorder that leads to organ damage via increased iron uptake and deposition. This case report describes a 25-year-old man who presented with acute liver failure and severe hemolytic anemia. Workup revealed that not only did he have a rare presentation of Epstein-Barr virus-induced acute liver failure and C<sub>3</sub>-positive IgG-negative hemolytic anemia, he also had previously undiagnosed hereditary hemochromatosis. This combined presentation of these pathologies presents a unique opportunity to study their interaction and possible synergistic pathophysiology. Furthermore, the evolving understanding of the disease mechanisms behind these disease processes is described.


2014 ◽  
Vol 59 (7) ◽  
pp. 1630-1637 ◽  
Author(s):  
Jessica L. Mellinger ◽  
Lorenzo Rossaro ◽  
Willscott E. Naugler ◽  
Satish N. Nadig ◽  
Henry Appelman ◽  
...  

2020 ◽  
Vol 17 (4) ◽  
Author(s):  
Prabhar Srivastava ◽  
Ravi Sharma ◽  
Preeti Kharwas

2021 ◽  
Vol 51 (1) ◽  
pp. 46-48
Author(s):  
Tom Kamal ◽  
Nadim Haboubi ◽  

Epstein-Barr virus (EBV) associated acute liver failure (ALF) is an exceedingly uncommon event. Despite this, EBV-associated ALF has a very high fatality rate. When looking at the number of reported cases of EBV-associated ALF requiring an emergency liver transplant, we see even fewer numbers. This presents challenges to clinicians in the diagnosis, awareness and appropriate case management. There is limited information in the medical literature about the hepatic demonstration and complications of EBV. We therefore report a case of EBV-associated ALF in a 17-year-old immunocompetent female who was treated successfully with an orthotopic liver transplantation.


2016 ◽  
Vol 9 (4-5) ◽  
pp. 74-78 ◽  
Author(s):  
Wei Zhang ◽  
Betty Chen ◽  
Yongxin Chen ◽  
Robin Chamberland ◽  
Alexa Fider-Whyte ◽  
...  

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