Initial therapy with the fixed-dose combination of sitagliptin and metformin results in greater improvement in glycaemic control compared with pioglitazone monotherapy in patients with type 2 diabetes

2011 ◽  
Vol 14 (5) ◽  
pp. 409-418 ◽  
Author(s):  
J. Wainstein ◽  
L. Katz ◽  
S. S. Engel ◽  
L. Xu ◽  
G. T. Golm ◽  
...  
Keyword(s):  
Type 2 Diabetes ◽  
Glycaemic Control ◽  
Initial Therapy ◽  
Fixed Dose Combination ◽  
Fixed Dose ◽  
Dose Combination

Rosiglitazone Maleate and Metformin Hydrochloride in Fixed Combination: What Role in the Treatment of Type 2 Diabetes?

2009 ◽  
Vol 1 ◽  
pp. CMT.S2389
Author(s):  
Raymond Farah
Keyword(s):  
Type 2 Diabetes ◽  
Initial Therapy ◽  
Fixed Dose Combination ◽  
Fixed Dose ◽  
Metformin Hydrochloride ◽  
Tolerability Profile ◽  
Volume Depletion ◽  
Dose Combination ◽  
High Doses

Traditional first-line intervention in patients with type 2 diabetes and very poor glycemic control is insulin therapy or high doses of sulfanylureas if there is no evidence of volume depletion. This review assesses the efficacy and safety of rosiglitazone and metformin fixed dose combination (avandamet) as initial therapy in patients with uncontrolled type 2 diabetes. This combination therapy achieved significant reduction in A1c and fasting plasma glucose compared with either rosiglitazone or metformin monotherapy as demonstrated by various studies. This combination was generally well tolerated as initial therapy, with no new tolerability issue identified with the fixed-dose combination, with tolerability profile similar to metformin alone. The marked benefit of this combination is the product of the complementary actions of these two agents.

135-OR: The Effect of Fixed-Dose Combination of Insulin Degludec and Liraglutide on Serum Lipoprotein Metabolism in Patients with Type 2 Diabetes Mellitus

Diabetes ◽  
2020 ◽  
Vol 69 (Supplement 1) ◽  
pp. 135-OR
Author(s):  
ELENI PAPPA ◽  
CHRISTINA KOSTARA ◽  
CONSTANTINOS TELLIS ◽  
ALEXANDROS D. TSELEPIS ◽  
ELENI BAIRAKTARI ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Lipoprotein Metabolism ◽  
Serum Lipoprotein ◽  
Insulin Degludec ◽  
Fixed Dose Combination ◽  
Fixed Dose ◽  
Dose Combination
Sign in / Sign up

Export Citation Format

Share Document