Unilateral renal agenesis and the congenital solitary functioning kidney: developmental, genetic and clinical perspectives

2007 ◽  
Vol 99 (1) ◽  
pp. 17-21 ◽  
Author(s):  
ADRIAN S. WOOLF ◽  
KATHERINE A. HILLMAN
Author(s):  
Michiel F. Schreuder

The main cause for unilateral non-formation or non-functioning of a kidney can be found in renal agenesis/aplasia and multicystic dysplastic kidney. Even though kidney donation at adult age is considered safe, studies in recent years have shown that this may be different in congenital solitary functioning kidneys. Whether this is based on dysplasia in the remaining kidney or based on glomerular hyperfiltration damage, follow-up has shown renal injury, defined as hypertension and/or proteinuria, in up to 32% of children with a congenital solitary functioning kidney. Therefore, long-term infrequent follow-up of all patients with a congenital solitary functioning kidney seems to be indicated.


2021 ◽  
Vol 9 ◽  
Author(s):  
Mark J. C. M. van Dam ◽  
Bas S. H. J. Zegers ◽  
Michiel F. Schreuder

Unilateral renal agenesis and multicystic dysplastic kidney, resulting in a contralateral solitary functioning kidney (SFK), are part of the broad spectrum of congenital anomalies of the kidney and urinary tract (CAKUT). In girls with SFK, screening for asymptomatic Müllerian anomalies of uterus and vagina is not yet routinely performed, and therefore often overlooked until clinical complications in the menstrual cycle or fertility process occur. In this case series, we report on four teenagers with congenital SFK presenting with menstrual problems due to a Müllerian anomaly. Routine peri-menarchal screening for Müllerian anomalies in girls with SFK may provide timely counseling, surgical treatment and prevention of associated complications such as endometriosis, infertility and miscarriages.


Author(s):  
Sander Groen in’t Woud ◽  
Loes F. M. van der Zanden ◽  
Michiel F. Schreuder

2014 ◽  
Vol 2014 (dec24 1) ◽  
pp. bcr2014206205-bcr2014206205 ◽  
Author(s):  
S. Kumar ◽  
S. Singh ◽  
K. M. Parmar ◽  
N. Garg

2005 ◽  
Vol 133 (1) ◽  
pp. 64-67 ◽  
Author(s):  
T. Morita ◽  
Y. Michimae ◽  
M. Sawada ◽  
T. Uemura ◽  
Y. Araki ◽  
...  

2006 ◽  
Vol 47 (9) ◽  
pp. 1019 ◽  
Author(s):  
Yong Duk You ◽  
Kong Jo Kim ◽  
Hee Jo Yang ◽  
Hyun Ki Jo ◽  
Doo Sang Kim ◽  
...  

1985 ◽  
Vol 10 (4) ◽  
pp. 270-273 ◽  
Author(s):  
WILLIAM H. HOWARD ◽  
STEPHEN R. BUNKER ◽  
ROBERT D. KARL ◽  
THOMAS RALSTON ◽  
MICHAEL F. HARTSHORNE ◽  
...  

2018 ◽  
Vol 34 (3) ◽  
pp. 465-474 ◽  
Author(s):  
Isabel V. Poggiali ◽  
Ana Cristina Simões e Silva ◽  
Mariana A. Vasconcelos ◽  
Cristiane S. Dias ◽  
Izabella R. Gomes ◽  
...  

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