Effect of Strict Metabolic Control on Regulation of Subcutaneous Blood Flow in Insulin-dependent Diabetic Patients

1987 ◽  
Vol 4 (1) ◽  
pp. 30-36 ◽  
Author(s):  
J. Kastrup ◽  
E. R. Mathiesen ◽  
N. Saurbrey ◽  
T. Nørgaard ◽  
H.-H. Parving ◽  
...  
Keyword(s):  
Blood Flow ◽  
Metabolic Control ◽  
Diabetic Patients ◽  
Insulin Dependent ◽  
Subcutaneous Blood Flow ◽  
Insulin Dependent Diabetic

Decreased distensibility of resistance vessels of the skin in type 1 (insulin-dependent) diabetic patients with microangiopathy

1987 ◽  
Vol 72 (1) ◽  
pp. 123-130 ◽  
Author(s):  
J. Kastrup ◽  
T. Nørgaard ◽  
H.-H. Parving ◽  
N. A. Lassen
Keyword(s):  
Blood Flow ◽  
Inverse Correlation ◽  
Diabetic Patients ◽  
Resistance Vessels ◽  
Head Up Tilt ◽  
Insulin Dependent ◽  
Insulin Dependent Diabetic ◽  
Type 1 Diabetic Patients ◽  
Term Type

1. The distensibility of the resistance vessels of the skin at the dorsum of the foot was determined in 11 long-term type 1 (insulin-dependent) diabetic patients with nephropathy and retinopathy, nine short-term type 1 diabetic patients without clinical microangiopathy and in nine healthy non-diabetic subjects. 2. Blood flow was measured by the local 133Xexenon washout technique in a vascular bed locally paralysed by the injection of histamine. Blood flow was measured before, during and after a 40 mmHg increase of the vascular transmural pressure, induced by head-up tilt. 3. The mean increase in blood flow during headup tilt was only 24% in diabetic subjects with and 48% in diabetic patients without clinical microangiopathy, compared with 79% in normal non-diabetic subjects (P < 0.0005 and P < 0.05, respectively). 4. An inverse correlation between microvascular distensibility and degree of hyalinosis of the terminal arterioles in biopsies from the skin was demonstrated (r = − 0.57, P < 0.001). 5. Our results suggest that terminal arteriolar hyalinosis reduces the microvascular distensibility and probably increases the minimal vascular resistance, thereby impeding hyperaemic responses.

scholarly journals Metabolic control of non-insulin-dependent diabetic patients undergoing cataract surgery: comparison of local and general anaesthesia

1995 ◽  
Vol 74 (5) ◽  
pp. 500-505 ◽  
Author(s):  
J.P. BARKER ◽  
P.N. ROBINSON ◽  
G.C. VAFIDIS ◽  
J.M. BURRIN ◽  
S. SAPSED-BYRNE ◽  
...  
Keyword(s):  
Cataract Surgery ◽  
General Anaesthesia ◽  
Metabolic Control ◽  
Diabetic Patients ◽  
Insulin Dependent ◽  
Insulin Dependent Diabetic

scholarly journals The effect of metabolic control on leucine metabolism in Type 1 (insulin-dependent) diabetic patients

Diabetologia ◽  
1986 ◽  
Vol 29 (3) ◽  
pp. 131-141 ◽  
Author(s):  
A. M. Umpleby ◽  
M. A. Boroujerdi ◽  
P. M. Brown ◽  
E. R. Carson ◽  
P. H. Sönksen
Keyword(s):  
Metabolic Control ◽  
Diabetic Patients ◽  
Leucine Metabolism ◽  
Insulin Dependent ◽  
Insulin Dependent Diabetic

scholarly journals Effect of improved metabolic control on loss of kidney function in Type 1 (insulin-dependent) diabetic patients: an update of the Steno studies

Diabetologia ◽  
1991 ◽  
Vol 34 (3) ◽  
pp. 164-170 ◽  
Author(s):  
B. Feldt-Rasmussen ◽  
E. R. Mathiesen ◽  
T. Jensen ◽  
T. Lauritzen ◽  
T. Deckert
Keyword(s):  
Metabolic Control ◽  
Kidney Function ◽  
Diabetic Patients ◽  
Insulin Dependent ◽  
Insulin Dependent Diabetic

The effect of metabolic control on hemodynamics in short-term insulin-dependent diabetic patients

Diabetes ◽  
1985 ◽  
Vol 34 (12) ◽  
pp. 1301-1305 ◽  
Author(s):  
E. R. Mathiesen ◽  
J. Hilsted ◽  
B. Feldt-Rasmussen ◽  
F. Bonde-Petersen ◽  
N. J. Christensen ◽  
...  
Keyword(s):  
Metabolic Control ◽  
Diabetic Patients ◽  
Short Term ◽  
Insulin Dependent ◽  
Insulin Dependent Diabetic
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