scholarly journals The contribution of Rb-permeable potassium channels to the relaxant and membrane hyperpolarizing actions of cromakalim, RP49356 and diazoxide in bovine tracheal smooth muscle

1991 ◽  
Vol 102 (4) ◽  
pp. 979-985 ◽  
Author(s):  
J. Longmore ◽  
K.M. Bray ◽  
A.H. Weston
Keyword(s):  
Smooth Muscle ◽  
Potassium Channels ◽  
Tracheal Smooth Muscle

scholarly journals Cyclic GMP-dependent but G-kinase-independent inhibition of Ca2+-dependent Cl−currents by NO donors in cat tracheal smooth muscle

1998 ◽  
Vol 511 (3) ◽  
pp. 719-731 ◽  
Author(s):  
Yoshiki Waniishi ◽  
Ryuji Inoue ◽  
Hiromitsu Morita ◽  
Noriyoshi Teramoto ◽  
Kihachiro Abe ◽  
...  
Keyword(s):  
Smooth Muscle ◽  
Cyclic Gmp ◽  
Tracheal Smooth Muscle ◽  
No Donors

scholarly journals Remodeling of Arterial Tone Regulation in Postnatal Development: Focus on Smooth Muscle Cell Potassium Channels

2021 ◽  
Vol 22 (11) ◽  
pp. 5413
Author(s):  
Anastasia A. Shvetsova ◽  
Dina K. Gaynullina ◽  
Olga S. Tarasova ◽  
Rudolf Schubert
Keyword(s):  
Smooth Muscle ◽  
Potassium Channels ◽  
Potassium Channel ◽  
Postnatal Development ◽  
Sympathetic Innervation ◽  
Treatment Strategies ◽  
Muscle Membrane ◽  
Postnatal Life ◽  
Vascular Control ◽  
Bkca Channels

Maturation of the cardiovascular system is associated with crucial structural and functional remodeling. Thickening of the arterial wall, maturation of the sympathetic innervation, and switching of the mechanisms of arterial contraction from calcium-independent to calcium-dependent occur during postnatal development. All these processes promote an almost doubling of blood pressure from the moment of birth to reaching adulthood. This review focuses on the developmental alterations of potassium channels functioning as key smooth muscle membrane potential determinants and, consequently, vascular tone regulators. We present evidence that the pattern of potassium channel contribution to vascular control changes from Kir2, Kv1, Kv7 and TASK-1 channels to BKCa channels with maturation. The differences in the contribution of potassium channels to vasomotor tone at different stages of postnatal life should be considered in treatment strategies of cardiovascular diseases associated with potassium channel malfunction.

scholarly journals Theophylline attenuates Ca2+ sensitivity and modulates BK channels in porcine tracheal smooth muscle

2003 ◽  
Vol 140 (5) ◽  
pp. 939-947 ◽  
Author(s):  
Shinji Ise ◽  
Junji Nishimura ◽  
Katsuya Hirano ◽  
Nobuyuki Hara ◽  
Hideo Kanaide
Keyword(s):  
Smooth Muscle ◽  
Bk Channels ◽  
Tracheal Smooth Muscle
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