scholarly journals Effects of cytochrome P450 inhibitors on potassium currents and mechanical activity in rat portal vein

1996 ◽  
Vol 119 (4) ◽  
pp. 691-701 ◽  
Author(s):  
Gillian Edwards ◽  
Peter M. Zygmunt ◽  
Edward D. Högestätt ◽  
Arthur H. Weston
Keyword(s):  
Cytochrome P450 ◽  
Portal Vein ◽  
Potassium Currents ◽  
Mechanical Activity ◽  
Rat Portal Vein ◽  
P450 Inhibitors

Mechanisms of endothelin-induced augmentation of the electrical and mechanical activity in rat portal vein

1990 ◽  
Vol 415 (5) ◽  
pp. 526-532 ◽  
Author(s):  
K. Nakao ◽  
Y. Inoue ◽  
M. Oike ◽  
K. Kitamura ◽  
H. Kuriyama
Keyword(s):  
Portal Vein ◽  
Mechanical Activity ◽  
Rat Portal Vein

Strontium and Barium as Substitutes for Calcium on Electrical and Mechanical Activity in Rat Portal Vein

1974 ◽  
Vol 11 (5-6) ◽  
pp. 245-259 ◽  
Author(s):  
Bengt Uvelius ◽  
Stefan B. Sigurdsson ◽  
Börje Johansson
Keyword(s):  
Portal Vein ◽  
Mechanical Activity ◽  
Rat Portal Vein

Modifications evoked by piretanide in the mechanical activity of cardiovascular tissues

1985 ◽  
Vol 63 (4) ◽  
pp. 283-286
Author(s):  
J. L. Lacuara ◽  
R. D. Ruiz ◽  
M. Fiol de Cuneo
Keyword(s):  
Portal Vein ◽  
Contractile Activity ◽  
Mechanisms Of Action ◽  
Mechanical Activity ◽  
Vascular Tissues ◽  
Cardiovascular Tissues ◽  
Rat Portal Vein ◽  
Isolated Rat

The effects of piretanide upon mechanical activity and pharmacological reactivity of vascular and myocardial tissues from normotensive rats were investigated. Magnitude of phasic contractions of isolated rat portal vein was diminished by the drug in a dose-related manner; contractile depression induced by piretanide (10−4 M) was less in the presence of insulin (0.1 U/mL), glucose (22 mM) or pyruvate (5 mM). Responses to KCl (90 mM), or norepinephrine (2.5 × 10−5 M) were also reduced. Contractile activity of atria and ventricle strips was diminished only when piretanide reached 10−4 M. Results support direct actions of piretanide upon cardiac and vascular tissues. Possible mechanisms of action are discussed.

scholarly journals Influence of the lonic Environment on Spontaneous Electrical and Mechanical Activity of the Rat Portal Vein

1967 ◽  
Vol 21 (5) ◽  
pp. 609-618 ◽  
Author(s):  
JOHANN AXELSSON ◽  
BO WAHLSTROöm ◽  
Börje JOHANSSON ◽  
OLOF JONSSON
Keyword(s):  
Portal Vein ◽  
Mechanical Activity ◽  
Rat Portal Vein
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