Inhibition of Acyl-CoA Cholesterol Acyltransferase by F12511 (Eflucimibe): Could it be a New Antiatherosclerotic Therapeutic?

Cardiovascular Drug Reviews ◽

10.1111/j.1527-3466.2007.00030.x ◽

2008 ◽

Vol 26 (1) ◽

pp. 65-74 ◽

Author(s):

Antonio José López-Farré ◽

Daniel Sacristán ◽

José J. Zamorano-León ◽

Nuria San-Martín ◽

Carlos Macaya

Keyword(s):

Cholesterol Acyltransferase

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LECITHIN-CHOLESTEROL-ACYLTRANSFERASE (LCAT) ACTIVITY IN HYPER- AND HYPOTHYROIDISM

Acta Endocrinologica ◽

10.1530/acta.0.072s143 ◽

1973 ◽

Vol 71 (4_Suppl) ◽

pp. S143 ◽

Author(s):

F. Adlkofer ◽

U. Armbrecht ◽

H. Schleusener

Keyword(s):

Cholesterol Acyltransferase ◽

Lcat Activity ◽

Lecithin Cholesterol Acyltransferase

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Lipid and Lipoprotein Abnormalities in Liver Disease: The Possible Role of Lecithin: Cholesterol Acyltransferase Deficiency

Scandinavian Journal of Clinical and Laboratory Investigation ◽

10.3109/00365517409100639 ◽

1974 ◽

Vol 33 ◽

pp. 115-120 ◽

Author(s):

N. McIntyre ◽

S. Calandra ◽

A. J. G. Pearson

Keyword(s):

Liver Disease ◽

Cholesterol Acyltransferase ◽

Lecithin Cholesterol Acyltransferase

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Familial Lecithin: Cholesterol Acyltransferase Deficiency: Report of a Third Norwegian Family with Two Afflicted Members

Scandinavian Journal of Clinical and Laboratory Investigation ◽

10.3109/00365517409100637 ◽

1974 ◽

Vol 33 ◽

pp. 101-105 ◽

Author(s):

E. Gjone ◽

A. J. Skarbövik ◽

J. P. Blomhoff ◽

P. Teisberg

Keyword(s):

Cholesterol Acyltransferase ◽

Lecithin Cholesterol Acyltransferase

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Lecithin: Cholesterol Acyltransferase of Human Plasma. Role of Chylomicrons, Very Low, and High Density Lipoproteins in the Reaction

Scandinavian Journal of Clinical and Laboratory Investigation ◽

10.3109/00365517409100628 ◽

1974 ◽

Vol 33 ◽

pp. 45-48 ◽

Author(s):

Yves Marcel ◽

Camilla Vezina

Keyword(s):

Human Plasma ◽

Cholesterol Acyltransferase ◽

High Density ◽

High Density Lipoproteins ◽

Lecithin Cholesterol Acyltransferase

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Studies on Enzymatic and Molecular Properties of Lecithin: Cholesterol Acyltransferase

Scandinavian Journal of Clinical and Laboratory Investigation ◽

10.3109/00365517409100626 ◽

1974 ◽

Vol 33 ◽

pp. 29-34 ◽

Author(s):

A. G. Lacko ◽

K. G. Varma ◽

H. L. Rutenberg ◽

L. A. Soloff

Keyword(s):

Cholesterol Acyltransferase ◽

Molecular Properties ◽

Lecithin Cholesterol Acyltransferase

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Plasma Lipoproteins in Familial Lecithin:Cholesterol Acyltransferase Deficiency: Effects of Incubation with Lecithin: Cholesterol Acyltransferase in vitro

Scandinavian Journal of Clinical and Laboratory Investigation ◽

10.3109/00365517509108158 ◽

1975 ◽

Vol 35 ◽

pp. 31-55 ◽

Author(s):

Kaare Norum ◽

John Glomset ◽

Alex Nichols ◽

Trudy Forte ◽

John Albers ◽

...

Keyword(s):

Cholesterol Acyltransferase ◽

Plasma Lipoproteins ◽

Lecithin:Cholesterol Acyltransferase ◽

Lecithin Cholesterol Acyltransferase

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An Update of Acyl-CoA: Cholesterol Acyltransferase Inhibition in Animal and Human In Vitro and In Vivo Models of Atherosclerosis

Current Medicinal Chemistry - Immunology Endocrine & Metabolic Agents ◽

10.2174/1568013013359113 ◽

2001 ◽

Vol 1 (2) ◽

pp. 141-150

Author(s):

J. wu ◽

R. Doshi ◽

A. Rodriguez

Keyword(s):

Cholesterol Acyltransferase ◽

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Biochemical and biophysical characterization of human recombinant lecithin: cholesterol acyltransferase

The Journal of Lipid Research ◽

10.1016/s0022-2275(20)37191-1 ◽

1997 ◽

Vol 38 (6) ◽

pp. 1085-1093

Author(s):

L Jin ◽

Y P Lee ◽

A Jonas

Keyword(s):

Cholesterol Acyltransferase ◽

Biophysical Characterization ◽

Lecithin Cholesterol Acyltransferase

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Rabbit and human liver contain a novel pentacyclic triterpene ester with acyl-CoA: cholesterol acyltransferase inhibitory activity.

Journal of Biological Chemistry ◽

10.1016/s0021-9258(19)39036-2 ◽

1990 ◽

Vol 265 (14) ◽

pp. 8042-8051

Author(s):

I Tabas ◽

L L Chen ◽

J W Clader ◽

A T McPhail ◽

D A Burnett ◽

...

Keyword(s):

Inhibitory Activity ◽

Human Liver ◽

Cholesterol Acyltransferase ◽

Pentacyclic Triterpene

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Reaction of human lecithin cholesterol acyltransferase with synthetic micellar complexes of apolipoprotein A-I, phosphatidylcholine, and cholesterol.

Journal of Biological Chemistry ◽

10.1016/s0021-9258(18)34757-4 ◽

1982 ◽

Vol 257 (8) ◽

pp. 4541-4546 ◽

Author(s):

C E Matz ◽

A Jonas

Keyword(s):

Cholesterol Acyltransferase ◽

Lecithin Cholesterol Acyltransferase ◽

Apolipoprotein A

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