scholarly journals Effects of Negative Pressure Wound Therapy on Healing of Free Full-Thickness Skin Grafts in Dogs

2013 ◽  
Vol 42 (5) ◽  
pp. 511-522 ◽  
Author(s):  
Bryden J. Stanley ◽  
Kathryn A. Pitt ◽  
Christian D. Weder ◽  
Michele C. Fritz ◽  
Joe G. Hauptman ◽  
...  
2017 ◽  
Vol 2 (3) ◽  
pp. 2473011417S0000
Author(s):  
Ji-Yong Ahn

Category: Diabetes Introduction/Purpose: Infected diabetes mellitus (DM) foot has been controlled with amputation. After performing the amputation with preserving enough length of the foot due to functional and cosmetic advantages, remaining wounds have been covered with split thickness skin graft (STSG) despite of sacrifice of donor site with pain and scar. We hypothesized outcomes of full thickness skin graft (FTSG) combined with negative pressure wound therapy (NPWT) can be an alternative STSG. The aim of this study was to investigate clinical outcomes of FTSG combined with negative pressure wound therapy in DM foot infection. Methods: This study included 21 patients of infected DM foot (21 feet). There were 20 cases of midfoot and 1 case of hindfoot. We performed the amputation and combined NPWT at a mean age of 51.7 years (37 to 81) with the mean 12 months follow-up between June, 2014, and January, 2016. FTSG was performed after sufficient granulation healing of DM foot amputee. We measured multiple risk factors preoperatively and postoperatively. The wound healing after FTSG was evaluated during the followup. The relationship between outcomes of FTSG and multiple risk factors were evaluated. Results: 20 feet showed complete healing of wound. One foot showed failed wound healing. Mean NPWT number of times before the FTSG were 11. Mean C-reactive protein (CRP) values and Hemoglobin A1C (HbA1C) were 1.24 and 9.21 just before FTSG, respectively. There were no significant correlations between wound healing and risk factors (CRP, HbA1C) (p=0.223, p=0.175). Conclusion: Full thickness skin graft combined with negative pressure wound therapy (NPWT) can be the treatment of choice for the diabetes mellitus foot amputee as an alternative STSG.


2017 ◽  
Vol 46 (3) ◽  
pp. 389-395 ◽  
Author(s):  
Matan Or ◽  
Bart Van Goethem ◽  
Adriaan Kitshoff ◽  
Annika Koenraadt ◽  
Ilona Schwarzkopf ◽  
...  

Burns ◽  
2014 ◽  
Vol 40 (6) ◽  
pp. 1116-1120 ◽  
Author(s):  
Michael Hoeller ◽  
Michael Valentin Schintler ◽  
Klaus Pfurtscheller ◽  
Lars-Peter Kamolz ◽  
Norbert Tripolt ◽  
...  

2008 ◽  
Vol 60 (6) ◽  
pp. 661-666 ◽  
Author(s):  
Alex G. Landau ◽  
Don A. Hudson ◽  
Kevin Adams ◽  
Stuart Geldenhuys ◽  
Conrad Pienaar

2019 ◽  
Vol 28 (Sup8) ◽  
pp. S16-S21
Author(s):  
Yusuke Inatomi ◽  
Hideki Kadota ◽  
Kenichi Kamizono ◽  
Masuo Hanada ◽  
Sei Yoshida

Objective: Negative-pressure wound therapy (NPWT) is generally applied as a bolster for split-thickness skin grafts (STSG) after the graft has been secured with sutures or skin staples. In this study, NPWT was applied to secure STSGs without any sutures or staples. Surgical outcomes of using NPWT without sutures was compared with a control group. Methods: Patients with STSGs were divided into two groups: a ‘no suture’ group using only NPWT, and a control group using conventional fixings. In the no suture group, the grafts were covered with meshed wound dressing and ointment. The NPWT foam was placed over the STSG and negative pressure applied. In the control group, grafts were fixed in place using tie-over bolster, securing with fibrin glue, or NPWT after sutures. Results: A total of 30 patients with 35 graft sites participated in the study. The mean rate of graft take in the no suture group was 95.1%, compared with 93.3% in the control group, with no significant difference between them. No graft shearing occurred in the no suture group. Although the difference did not reach statistical significance, mean surgical time in the no suture group (31.5 minutes) tended to be shorter than that in the control group (55.7 minutes). Conclusion: By eliminating sutures, the operation time tended to be shorter, suturing was avoided and suture removal was not required meaning that patients could avoid the pain associated with this procedure. Furthermore, the potential for staple retention and its associated complications was avoided, making this method potentially beneficial for both medical staff and patients.


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