Performance evaluation of the new fully automated human immunodeficiency virus antigen-antibody combination assay designed for blood screening

Transfusion ◽  
2008 ◽  
Vol 48 (4) ◽  
pp. 584-593 ◽  
Author(s):  
Eva Sickinger ◽  
Gesa Jonas ◽  
Alex W. Yem ◽  
Andreas Goller ◽  
Myriam Stieler ◽  
...  
Keyword(s):  
Human Immunodeficiency Virus ◽  
Performance Evaluation ◽  
Virus Antigen ◽  
Immunodeficiency Virus ◽  
Antigen Antibody ◽  
Blood Screening

Performance evaluation of three automated human immunodeficiency virus antigen–antibody combination immunoassays

2006 ◽  
Vol 133 (1) ◽  
pp. 20-26 ◽  
Author(s):  
Jung-Ah Kwon ◽  
Soo-Young Yoon ◽  
Chang-Kyu Lee ◽  
Chae Seung Lim ◽  
Kap No Lee ◽  
...  
Keyword(s):  
Human Immunodeficiency Virus ◽  
Performance Evaluation ◽  
Virus Antigen ◽  
Immunodeficiency Virus ◽  
Antigen Antibody

scholarly journals Evaluation of performance of human immunodeficiency virus antigen/antibody combination assays in Taiwan

2017 ◽  
Vol 50 (4) ◽  
pp. 440-447 ◽  
Author(s):  
Chun-Kai Chang ◽  
Cheng-Feng Kao ◽  
Pi-Han Lin ◽  
Hui-Lin Huang ◽  
Shu-Yuan Ho ◽  
...  
Keyword(s):  
Human Immunodeficiency Virus ◽  
Virus Antigen ◽  
Evaluation Of Performance ◽  
Immunodeficiency Virus ◽  
Antigen Antibody

scholarly journals Development of External Quality Controls for Human Immunodeficiency Virus Antigen/Antibody Tests in Korea

2018 ◽  
Vol 40 (2) ◽  
pp. 92-100
Author(s):  
Dong Hee Seo ◽  
Yeo Rin Choi ◽  
Won Woong Choi ◽  
Cheol Hee Yoon ◽  
Byeong Sun Choi ◽  
...  
Keyword(s):  
Human Immunodeficiency Virus ◽  
Virus Antigen ◽  
External Quality ◽  
Quality Controls ◽  
Immunodeficiency Virus ◽  
Antigen Antibody ◽  
Antibody Tests

scholarly journals Acute Infections, Cost per Infection and Turnaround Time in Three United States Hospital Laboratories Using Fourth-Generation Antigen-Antibody Human Immunodeficiency Virus Immunoassays

2015 ◽  
Vol 3 (1) ◽  
Author(s):  
Laura G. Wesolowski ◽  
Muazzam Nasrullah ◽  
Robert W. Coombs ◽  
Eric Rosenberg ◽  
Steven F. Ethridge ◽  
...  
Keyword(s):  
Human Immunodeficiency Virus ◽  
South Carolina ◽  
Massachusetts General Hospital ◽  
Medical Center ◽  
Fourth Generation ◽  
Reference Laboratory ◽  
Acute Infections ◽  
Immunodeficiency Virus ◽  
Antigen Antibody ◽  
Hiv 1

Abstract Background.  To improve clinical and public health outcomes through early human immunodeficiency virus (HIV) detection, fourth-generation antigen/antibody immunoassay (4IA) and supplemental testing results must be returned rapidly. Methods.  We examined HIV testing data at Harborview Medical Center (HMC), Massachusetts General Hospital (MGH), and the Medical University of South Carolina (MUSC), which used 4IA and supplemental antibody and nucleic acid tests (NATs). At MGH and MUSC, HIV-1 Western blot (WB) and HIV-2 testing were conducted at a reference laboratory. We compared time from specimen collection to laboratory result for established (positive WB) and acute infections (reactive 4IA, negative/indeterminate WB, detectable NAT), and we calculated testing cost per positive-test result. Results.  From 3731 (MUSC) to 19 774 (MGH) tests were conducted; 0.01% (MGH) to 0.05% (HMC) were acute infections. Each laboratory had reactive 4IA, WB-negative, or indeterminate specimens without NAT (ie, potential acute infections). Time to result was 1.5 (HMC) to 5.2 days (MGH) for acute and 1.0 (HMC) to 5.2 days (MGH) for established infections. Costs were $1054 (MGH) to $1521 (MUSC). Conclusions.  Conducting supplemental testing in-house lowered turnaround times, which may be further reduced with rapid HIV-1/HIV-2 differentiation tests. Hospitals may benefit from quantitative NATs not requiring physician orders, so all potential acute infections receive NAT.

scholarly journals Intra-blood-brain barrier synthesis of human immunodeficiency virus antigen and antibody in humans and chimpanzees.

1987 ◽  
Vol 84 (11) ◽  
pp. 3876-3880 ◽  
Author(s):  
J. Goudsmit ◽  
L. G. Epstein ◽  
D. A. Paul ◽  
H. J. van der Helm ◽  
G. J. Dawson ◽  
...  
Keyword(s):  
Human Immunodeficiency Virus ◽  
Blood Brain Barrier ◽  
Virus Antigen ◽  
Brain Barrier ◽  
Blood Brain ◽  
Immunodeficiency Virus

scholarly journals Evaluation of a New Vesion of the Human Immunodeficiency Virus Antigen and Antibody Combination Assay with Improved Sensitivity in HIV-1 p24 Antigen Detection

2013 ◽  
Vol 87 (4) ◽  
pp. 415-423 ◽  
Author(s):  
Takako SANO ◽  
Makiko KONDO ◽  
Yukihiro YOSHIMURA ◽  
Natsuo TACHIKAWA ◽  
Hiroko SAGARA ◽  
...  
Keyword(s):  
Human Immunodeficiency Virus ◽  
Virus Antigen ◽  
Antigen Detection ◽  
Immunodeficiency Virus ◽  
P24 Antigen ◽  
Hiv 1
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