Management of acute anemia in a Jehovah's Witness patient with acute lymphoblastic leukemia with polymerized bovine hemoglobin-based oxygen carrier: a case report and review of literature

Transfusion ◽  
2010 ◽  
Vol 50 (7) ◽  
pp. 1561-1567 ◽  
Author(s):  
Laura L. Donahue ◽  
Iuliana Shapira ◽  
Aryeh Shander ◽  
Jonathan Kolitz ◽  
Steven Allen ◽  
...  
Keyword(s):  
Case Report ◽  
Acute Lymphoblastic Leukemia ◽  
Lymphoblastic Leukemia ◽  
Oxygen Carrier ◽  
Bovine Hemoglobin ◽  
Review Of Literature ◽  
Jehovah’S Witness ◽  
Acute Anemia ◽  
Jehovah's Witness ◽  
Witness Patient

Bovine Hemoglobin

2012 ◽  
Vol 26 (3) ◽  
pp. 257-260 ◽  
Author(s):  
Shane D. Jordan ◽  
Earnest Alexander
Keyword(s):  
Oxygen Carrier ◽  
Blood Substitutes ◽  
Bovine Hemoglobin ◽  
Splenic Artery Embolization ◽  
Traditional Management ◽  
Jehovah’S Witness ◽  
Jehovah's Witness ◽  
Human Red Blood Cells ◽  
Therapeutic Alternatives ◽  
Witness Patient

Introduction: Management of severe symptomatic anemia in critically ill Jehovah’s Witness patients remains a challenge. The paucity of therapeutic alternatives to human red blood cells has prompted the use of blood substitutes. Case Report: A 19-year-old female Jehovah’s Witness patient presented to the emergency department following several episodes of syncope. She was found to have a positive Coombs test and was diagnosed with warm-bodied autoimmune hemolytic anemia. Upon admission, her hemoglobin was 8.4 g/dL, then dropped to a nadir of 2.8 g/dL 4 days later. She received traditional management with corticosteroids, intravenous immune globulin, rituximab, and partial splenic artery embolization. Despite these therapies, hemoglobin levels failed to respond, and she experienced signs of marked ischemia. A decision was made to give 2 units of Hemopure, a bovine hemoglobin-based oxygen carrier, and the hemoglobin levels increased to 8.7 g/dL 10 days later. The patient’s overall clinical condition improved leading to subsequent hospital discharge. Conclusion: This case exemplifies the ingenuity that health care practitioners must use in critical situations involving the medical management of anemic Jehovah’s Witness patients who refuse blood products. Hemopure was used as “bridging treatment” to help save a patient from the devastating effects of ischemia resulting from severe anemia.

Long-lasting extreme anemia during the therapy of acute lymphoblastic leukemia in a Jehovah's Witness patient

Transfusion ◽  
2016 ◽  
Vol 56 (10) ◽  
pp. 2438-2442 ◽  
Author(s):  
Krzysztof Chojnowski ◽  
Agnieszka Janus ◽  
Katarzyna Bliźniewska ◽  
Marta Robak ◽  
Jacek Treliński
Keyword(s):  
Acute Lymphoblastic Leukemia ◽  
Lymphoblastic Leukemia ◽  
Jehovah’S Witness ◽  
Jehovah's Witness ◽  
Witness Patient

Ovarian and multiple lymph nodes recurrence of acute lymphoblastic leukemia: a case report and review of literature

2008 ◽  
Vol 24 (11) ◽  
pp. 1269-1273 ◽  
Author(s):  
Jong Woon Kim ◽  
Moon Kyoung Cho ◽  
Cheol Hong Kim ◽  
Woo Dae Kang ◽  
Hoon Kook ◽  
...  
Keyword(s):  
Case Report ◽  
Acute Lymphoblastic Leukemia ◽  
Lymph Nodes ◽  
Lymphoblastic Leukemia ◽  
Review Of Literature
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