Effect of Ibutilide, a New Class III Agent, On Sustained Atrial Fibrillation in a Canine Model of Acute Ischemia and Myocardial Dysfunction Induced By Microembolization

1993 ◽  
Vol 16 (10) ◽  
pp. 1975-1983 ◽  
Author(s):  
MERVAT A. NABIH ◽  
PETAR PRCEVSKI ◽  
BARBARA S. FROMM ◽  
STEVEN J. LAVINE ◽  
MOHAMED ELNABTITY ◽  
...  
Keyword(s):  
Atrial Fibrillation ◽  
Myocardial Dysfunction ◽  
Canine Model ◽  
Acute Ischemia ◽  
Class Iii ◽  
New Class

Effects of a New Class III Antiarrhythmic Drug Nibentan in a Canine Model of Vagally Mediated Atrial Fibrillation

2000 ◽  
Vol 36 (1) ◽  
pp. 77-89 ◽  
Author(s):  
Vadim V. Fedorov ◽  
Oleg F. Sharifov ◽  
Galina G. Beloshapko ◽  
Anna V. Yushmanova ◽  
Leonid V. Rosenshtraukh
Keyword(s):  
Atrial Fibrillation ◽  
Antiarrhythmic Drug ◽  
Canine Model ◽  
Class Iii ◽  
New Class ◽  
Class Iii Antiarrhythmic Drug

553 Efficiency of new class III antiarrhythmic — Nibentan versus amiodarone for sinus rhythm restoration in paroxysmal atrial fibrillation patients

EP Europace ◽  
2005 ◽  
Vol 7 (Supplement_1) ◽  
pp. 121-121
Author(s):  
A. Ardashev ◽  
M. Kruchko ◽  
O. Vrublevskiy ◽  
A. Shavarov ◽  
M. Chernov ◽  
...  
Keyword(s):  
Atrial Fibrillation ◽  
Sinus Rhythm ◽  
Paroxysmal Atrial Fibrillation ◽  
Class Iii ◽  
New Class

scholarly journals Cardioversion of recent-onset atrial fibrillation using intravenous antiarrhythmics

2021 ◽  
Author(s):  
Samuel Levy
Keyword(s):  
Atrial Fibrillation ◽  
Real Life ◽  
Torsades De Pointes ◽  
Antiarrhythmic Agents ◽  
Success Rates ◽  
Class Iii ◽  
Recent Onset ◽  
New Class ◽  
Pharmacological Cardioversion ◽  
Onset Atrial Fibrillation

ABSTRACT (195 words) Pharmacological cardioversion using intravenous antiarrhythmic agents is commonly indicated in symptomatic patients with recent-onset atrial fibrillation (AF). Except in hemodynamically unstable patients who require emergency direct current electrical cardioversion, for the majority of hemodynamically stable patients, pharmacological cardioversion represents a valid option and requires the clinician to be familiar with the properties and use of antiarrhythmic agents. The main characteristics of selected intravenous antiarrhythmic agents for conversion of recent-onset AF, the reported success rates and possible adverse events are discussed. Among intravenous antiarrhythmics, flecainide, propafenone, amiodarone, sotalol, dofetilide, ibutilide and vernakalant are commonly used. Antazoline, an old antihistaminic agent with antiarrhythmic properties was also reported to give encouraging results. Intravenous flecainide and propafenone are the only class I agents still recommended by recent guidelines. Intravenous new class III agents as dofetilide and ibutilide have high and rapid efficacy in converting AF to sinus rhythm but require strict surveillance with ECG monitoring during and after intravenous administration because the potential risk of QT prolongation and Torsades de Pointes which can be prevented and properly managed. Vernakalant, a partial atrial selective was shown to have a high success rate and to be safe in real life use.

Efficacy of a New Class III Drug Niferidil in Cardioversion of Persistent Atrial Fibrillation and Flutter

2014 ◽  
Vol 64 (3) ◽  
pp. 247-255 ◽  
Author(s):  
Evgeny B. Maykov ◽  
Yulia A. Yuricheva ◽  
Nikolay Yu. Mironov ◽  
Sergey F. Sokolov ◽  
Sergey P. Golitsyn ◽  
...  
Keyword(s):  
Atrial Fibrillation ◽  
Persistent Atrial Fibrillation ◽  
Class Iii ◽  
New Class ◽  
Atrial Fibrillation And Flutter
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