Protection of Rats by Phospholipase C from Bacillus cereus against the Effects of Intravenous Infusions of Purified Tissue Thromboplastin

2009 ◽  
Vol 17 (4) ◽  
pp. 305-311 ◽  
Author(s):  
KARL-ERIK GIERCKSKY ◽  
EIRIK BJØRKLID
1972 ◽  
Vol 27 (2) ◽  
pp. 238-243 ◽  
Author(s):  
Anne-Brit Otnaess ◽  
Hans Prydz ◽  
Eirik Bjorklid ◽  
Ase Berre

Author(s):  
Ikezawa Hiroh ◽  
Yamanegi Masato ◽  
Taguchi Ryo ◽  
Miyashita Tomoyuki ◽  
Ohyabu Tetsuo

1975 ◽  
Author(s):  
A.-B. Otnœss

The effect on human platelets of phospholipase C (Bacillus cereus) has been studied. Platelets prepared by gel filtration lost 20-30% of their phospholipids when incubated with phospholipase C for 20 min. Phosphatidylethanolamine (PE) was reduced by about 50%, whereas phosphatidylcholine and phosphatidylserine were reduced each by about 20%. Sphingomyelin was not reduced.These data suggest an asymmetrical distribution of phospholipids in the platelet membrane, PE being more accessible and therefore probably mainly located in the outer part of the membrane.The loss of phospholipids was not accompanied by aggregation, nor did the platelets lose their ability to aggregate with thrombin or ADP. Data on release of serotonin, platelet factor 3 and 4 and scanning electron micrographs of treated platelets will be given.


1984 ◽  
Vol 16 (8) ◽  
pp. 931-934 ◽  
Author(s):  
Kjf.ll M. Aalmo ◽  
Jostein Krane ◽  
Clive Little ◽  
Carlyle B. Storm

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