Effects of the GABA Receptor Agonist Muscimol on the Turnover of Brain Dopamine and on the Motor Activity of Rats

2009 ◽  
Vol 44 (3) ◽  
pp. 191-196 ◽  
Author(s):  
Nils-Erik Andén ◽  
Maria Grabowska-Andén ◽  
Helmut Wachtel
Keyword(s):  
Motor Activity ◽  
Gaba Receptor ◽  
Receptor Agonist ◽  
Brain Dopamine ◽  
Gaba Receptor Agonist

POTENTIATION OF THE "DOPA" EFFECT IN PARKINSONISM BY A DIRECT GABA RECEPTOR AGONIST

The Lancet ◽  
1984 ◽  
Vol 323 (8376) ◽  
pp. 559 ◽  
Author(s):  
K.J. Bergmann ◽  
J.C.P. Limongi ◽  
Y.H. Lowe ◽  
M.R. Mendoza ◽  
M.D. Yahr
Keyword(s):  
Gaba Receptor ◽  
Receptor Agonist ◽  
Gaba Receptor Agonist

scholarly journals GABA and Muscimol as Reversible Inactivation Tools in Learning and Memory

2000 ◽  
Vol 7 (1-2) ◽  
pp. 19-29 ◽  
Author(s):  
M. Majchrzak ◽  
G. Di Scala
Keyword(s):  
Learning And Memory ◽  
Critical Analysis ◽  
Gaba Receptor ◽  
Receptor Agonist ◽  
Brain Areas ◽  
Reversible Inactivation ◽  
Brain Behavior ◽  
Gaba Receptor Agonist

Reversible inactivation of brain areas is a useful method for inferring brain-behavior relationships. Infusion of GABA or of the GABA receptor agonist muscimol is considered one interesting reversible inactivation method because it may not affect fibers of passage and may therefore be compared to axon-sparing types of lesions. This article reviews the data obtained with this method in learning and memory experiments. A critical analysis of data, collected in collaboration with Simon Brailowsky, with chronic GABA infusion is presented, together with an illustration of data obtained with muscimol-induced inactivation.

scholarly journals Bruxism Associated with Anoxic Encephalopathy: Successful Treatment with Baclofen

2013 ◽  
Vol 2013 ◽  
pp. 1-3
Author(s):  
A. Bruce Janati ◽  
Naif Saad ALGhasab ◽  
Fahad Saad ALGhassab
Keyword(s):  
Saudi Arabia ◽  
Gaba Receptor ◽  
Receptor Agonist ◽  
Clinical Investigation ◽  
Neurotransmitter System ◽  
The Third ◽  
Anoxic Encephalopathy ◽  
Comatose State ◽  
Convulsive Seizures ◽  
Gaba Receptor Agonist

Introduction. Bruxism is a movement disorder characterized by grinding and clenching of the teeth. Etiology of bruxism can be divided into three groups: psychosocial factors, peripheral factors, and pathophysiological factors.Methods. The clinical investigation was conducted at King Khaled Hospital in Hail, Saudi Arabia, in 2012.Results. A 16-year-old Saudi female was brought to the hospital in a comatose state and with generalized convulsive seizures secondary to acute anoxic encephalopathy. In the third week of hospitalization, while still in a state of akinetic mutism, she developed incessant bruxism which responded favorably to a GABA receptor agonist (baclofen).Conclusion. Our data support the hypothesis that bruxism emanates from imbalance or dysregulation of the neurotransmitter system. Larger scale studies will be needed to confirm this hypothesis.

GABA-receptor agonist, propofol inhibits invasion of colon carcinoma cells

2010 ◽  
Vol 64 (9) ◽  
pp. 583-588 ◽  
Author(s):  
Yufeng Miao ◽  
Youwei Zhang ◽  
Haijun Wan ◽  
Longbang Chen ◽  
Fangyu Wang
Keyword(s):  
Colon Carcinoma ◽  
Gaba Receptor ◽  
Receptor Agonist ◽  
Carcinoma Cells ◽  
Colon Carcinoma Cells ◽  
Gaba Receptor Agonist
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