Analysis of Crystal Structures of LXRβ in Relation to Plasticity of the Ligand-Binding Domain upon Ligand Binding

Nagulapalli Malini; Hariharan Rajesh; Pooja Berwal; Samiron Phukan; Vittukudi Narayanaiyengar Balaji

doi:10.1111/j.1747-0285.2007.00620.x

Analysis of Crystal Structures of LXRβ in Relation to Plasticity of the Ligand-Binding Domain upon Ligand Binding

Chemical Biology & Drug Design ◽

10.1111/j.1747-0285.2007.00620.x ◽

2008 ◽

Vol 71 (2) ◽

pp. 140-154 ◽

Cited By ~ 7

Author(s):

Nagulapalli Malini ◽

Hariharan Rajesh ◽

Pooja Berwal ◽

Samiron Phukan ◽

Vittukudi Narayanaiyengar Balaji

Keyword(s):

Ligand Binding ◽

Crystal Structures ◽

Binding Domain ◽

Ligand Binding Domain

Download Full-text

Faculty Opinions recommendation of X-ray crystal structures of the estrogen-related receptor-gamma ligand binding domain in three functional states reveal the molecular basis of small molecule regulation.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.1047292.497229 ◽

2006 ◽

Author(s):

Paul Webb

Keyword(s):

Ligand Binding ◽

Crystal Structures ◽

Small Molecule ◽

Molecular Basis ◽

Binding Domain ◽

Ligand Binding Domain ◽

X Ray ◽

Functional States ◽

Estrogen Related Receptor

Download Full-text

Faculty Opinions recommendation of Apo and InsP₃-bound crystal structures of the ligand-binding domain of an InsP₃ receptor.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.13323991.14688104 ◽

2011 ◽

Author(s):

Stephen Shears

Keyword(s):

Ligand Binding ◽

Crystal Structures ◽

Binding Domain ◽

Ligand Binding Domain

Download Full-text

Crystal Structures of Potent Dimeric Positive Allosteric Modulators at the Ligand-Binding Domain of the GluA2 Receptor

ACS Medicinal Chemistry Letters ◽

10.1021/acsmedchemlett.8b00369 ◽

2018 ◽

Vol 10 (3) ◽

pp. 243-247

Author(s):

Saara Laulumaa ◽

Kathrine Voigt Hansen ◽

Magdalena Masternak ◽

Thomas Drapier ◽

Pierre Francotte ◽

...

Keyword(s):

Ligand Binding ◽

Crystal Structures ◽

Binding Domain ◽

Ligand Binding Domain ◽

Allosteric Modulators ◽

Positive Allosteric Modulators

Download Full-text

Comparison of crystal structures of human androgen receptor ligand-binding domain complexed with various agonists reveals molecular determinants responsible for binding affinity

Protein Science ◽

10.1110/ps.051905906 ◽

2006 ◽

Vol 15 (5) ◽

pp. 987-999 ◽

Cited By ~ 149

Author(s):

Karine Pereira de Jésus-Tran ◽

Pierre-Luc Côté ◽

Line Cantin ◽

Jonathan Blanchet ◽

Fernand Labrie ◽

...

Keyword(s):

Androgen Receptor ◽

Ligand Binding ◽

Crystal Structures ◽

Binding Affinity ◽

Binding Domain ◽

Ligand Binding Domain ◽

Receptor Ligand ◽

Molecular Determinants ◽

Human Androgen Receptor

Download Full-text

First High-Resolution Crystal Structures of the Glucocorticoid Receptor Ligand-Binding Domain–Peroxisome Proliferator-Activated γ Coactivator 1-α Complex with Endogenous and Synthetic Glucocorticoids

Molecular Pharmacology ◽

10.1124/mol.119.116806 ◽

2019 ◽

Vol 96 (4) ◽

pp. 408-417 ◽

Cited By ~ 7

Author(s):

Xu Liu ◽

Yashuo Wang ◽

Eric A. Ortlund

Keyword(s):

High Resolution ◽

Glucocorticoid Receptor ◽

Ligand Binding ◽

Crystal Structures ◽

Binding Domain ◽

Ligand Binding Domain ◽

Peroxisome Proliferator ◽

Receptor Ligand ◽

Synthetic Glucocorticoids

Download Full-text

Correlating AMPA Receptor Activation and Cleft Closure across Subunits: Crystal Structures of the GluR4 Ligand-Binding Domain in Complex with Full and Partial Agonists†

Biochemistry ◽

10.1021/bi8013196 ◽

2008 ◽

Vol 47 (52) ◽

pp. 13831-13841 ◽

Cited By ~ 16

Author(s):

Avinash Gill ◽

Amanda Birdsey-Benson ◽

Brian L. Jones ◽

Leslie P. Henderson ◽

Dean R. Madden

Keyword(s):

Ligand Binding ◽

Crystal Structures ◽

Ampa Receptor ◽

Receptor Activation ◽

Binding Domain ◽

Ligand Binding Domain ◽

Partial Agonists ◽

Cleft Closure

Download Full-text

Ligand recognition by A‐class Eph receptors: crystal structures of the EphA2 ligand‐binding domain and the EphA2/ephrin‐A1 complex

EMBO Reports ◽

10.1038/embor.2009.91 ◽

2009 ◽

Vol 10 (7) ◽

pp. 722-728 ◽

Cited By ~ 72

Author(s):

Juha P Himanen ◽

Yehuda Goldgur ◽

Hui Miao ◽

Eugene Myshkin ◽

Hong Guo ◽

...

Keyword(s):

Ligand Binding ◽

Crystal Structures ◽

Binding Domain ◽

Ligand Binding Domain ◽

Ligand Recognition ◽

Eph Receptors

Download Full-text

Vitamin D Nuclear Receptor Ligand-Binding Domain Crystal Structures

Vitamin D ◽

10.1016/b978-012252687-9/50018-8 ◽

2005 ◽

pp. 279-289 ◽

Cited By ~ 1

Author(s):

NATACHA ROCHEL ◽

DINO MORAS

Keyword(s):

Vitamin D ◽

Ligand Binding ◽

Crystal Structures ◽

Nuclear Receptor ◽

Binding Domain ◽

Ligand Binding Domain ◽

Receptor Ligand

Download Full-text

X-ray Crystal Structures of the Estrogen-related Receptor-γ Ligand Binding Domain in Three Functional States Reveal the Molecular Basis of Small Molecule Regulation

Journal of Biological Chemistry ◽

10.1074/jbc.m608410200 ◽

2006 ◽

Vol 281 (49) ◽

pp. 37773-37781 ◽

Cited By ~ 93

Author(s):

Liping Wang ◽

William J. Zuercher ◽

Thomas G. Consler ◽

Millard H. Lambert ◽

Aaron B. Miller ◽

...

Keyword(s):

Ligand Binding ◽

Crystal Structures ◽

Small Molecule ◽

Molecular Basis ◽

Binding Domain ◽

Ligand Binding Domain ◽

X Ray ◽

Functional States ◽

Estrogen Related Receptor

Download Full-text

Apo and InsP3-bound crystal structures of the ligand-binding domain of an InsP3 receptor

Nature Structural & Molecular Biology ◽

10.1038/nsmb.2112 ◽

2011 ◽

Vol 18 (10) ◽

pp. 1172-1174 ◽

Cited By ~ 60

Author(s):

Chun-Chi Lin ◽

Kyuwon Baek ◽

Zhe Lu

Keyword(s):

Ligand Binding ◽

Crystal Structures ◽

Binding Domain ◽

Ligand Binding Domain ◽

Insp3 Receptor

Download Full-text