Functional Assessment of the Efficacy of Oxygen Free Radical Scavengers in the “No-Reflow” Phenomenon in Skeletal Muscle

1994 ◽  
Vol 723 (1) ◽  
pp. 418-419 ◽  
Author(s):  
D. A. O'FARRELL ◽  
L-E. CHEN ◽  
A. V. SEABER ◽  
J. R. URBANIAK
Keyword(s):  
Skeletal Muscle ◽  
Free Radical ◽  
Functional Assessment ◽  
Oxygen Free Radical ◽  
Free Radical Scavengers ◽  
Radical Scavengers ◽  
No Reflow ◽  
No Reflow Phenomenon

Experimental Evaluation of Oxygen Free Radical Scavengers in the Prevention of Reperfusion Injury to Skeletal Muscle

1989 ◽  
Vol 22 (4) ◽  
pp. 321-331 ◽  
Author(s):  
Axel Mario Feller ◽  
Allan C. Roth ◽  
Robert C. Russell ◽  
Bernard Eagleton ◽  
Hans Suchy ◽  
...  
Keyword(s):  
Skeletal Muscle ◽  
Free Radical ◽  
Reperfusion Injury ◽  
Experimental Evaluation ◽  
Oxygen Free Radical ◽  
Free Radical Scavengers ◽  
Radical Scavengers

Experimental Evaluation of Oxygen-free Radical Scavengers in the Prevention of Reperfusion Injury to Skeletal Muscle

1988 ◽  
Vol 21 (5) ◽  
pp. 500
Author(s):  
Axel Mario Feller ◽  
Allan C. Roth ◽  
Robert C. Russell ◽  
Bernard Eagleton ◽  
Hans Suchy ◽  
...  
Keyword(s):  
Skeletal Muscle ◽  
Free Radical ◽  
Reperfusion Injury ◽  
Experimental Evaluation ◽  
Oxygen Free Radical ◽  
Free Radical Scavengers ◽  
Radical Scavengers

Ultrastructural Evaluation of Ischemic Skeletal Muscle Reperfused with Oxygen Free Radical Scavengers

1988 ◽  
Vol 46 ◽  
pp. 262-263
Author(s):  
A. Mathur ◽  
R.C. Russell ◽  
A.C. Roth ◽  
D. Wagahoff
Keyword(s):  
Skeletal Muscle ◽  
Free Radical ◽  
White Male ◽  
Oxygen Free Radical ◽  
Free Radical Scavenger ◽  
Free Radical Scavengers ◽  
Radical Scavenger ◽  
Radical Scavengers ◽  
Tibialis Muscle ◽  
The Right

Skeletal muscle is very sensitive to ischemia. A prolonged preoperative ischemic interval decreases the chances for successful replantation of an amputated limb. Recent experimental work has implicated toxic oxygen free radicals produced during reperfusion of ischemic tissue to be responsible for some of the observed deleterious cellular changes. Selected oxygen free radical scavengers have been used to increase skeletal muscle survival following total ischemia. This study examined the effect of systemic administration of a superoxide free radical scavenger, superoxide dismutase (SOD), and a hydroxyl radical scavenger, dimethylsulfoxide (DMSO) just prior to reperfusion, on the ultrastructure and function of ischemic rabbit anterior tibialis muscle.White male New Zealand rabbits were used for this study. The right hind limb of each rabbit was made ischemic by dissecting and clamping the femoral artery and vein proximal to the bifurcation of the profundus artery and vein. A penrose tourniquet was also placed around the knee. The animals were divided into groups subjected to either 5 or 8 hours of ischemia.

scholarly journals Oxygen free radical scavengers reverse alterations to multiple proteins observed following myocardial stunning

2003 ◽  
Vol 41 (6) ◽  
pp. 373
Author(s):  
Melanie Y. White ◽  
Stuart J. Cordwell ◽  
Hugh C. McCarron ◽  
Adrian S. Tchen ◽  
George E. Craft ◽  
...  
Keyword(s):  
Free Radical ◽  
Myocardial Stunning ◽  
Oxygen Free Radical ◽  
Free Radical Scavengers ◽  
Radical Scavengers
Sign in / Sign up

Export Citation Format

Share Document