scholarly journals Herpes simplex virus conjunctival dendritic ulcer as a primary infection in an immunocompetent patient

2022 ◽  
Vol 100 (S267) ◽  
Author(s):  
Guillermo Pérez Rivasés ◽  
Maria Dolores Diaz Barreda ◽  
Ana Boned Murillo ◽  
Ismael Bakkali El Bakkali ◽  
Eva Josefina Nuñez Moscarda ◽  
...  
Keyword(s):  
Herpes Simplex Virus ◽  
Herpes Simplex ◽  
Primary Infection ◽  
Immunocompetent Patient ◽  
Simplex Virus

scholarly journals CD11c Controls Herpes Simplex Virus 1 Responses To Limit Virus Replication during Primary Infection

2011 ◽  
Vol 85 (19) ◽  
pp. 9945-9955 ◽  
Author(s):  
S. J. Allen ◽  
K. R. Mott ◽  
A. A. Chentoufi ◽  
L. BenMohamed ◽  
S. L. Wechsler ◽  
...  
Keyword(s):  
Herpes Simplex Virus ◽  
Herpes Simplex ◽  
Virus Replication ◽  
Primary Infection ◽  
Herpes Simplex Virus 1 ◽  
Simplex Virus

Bilateral Necrotizing Herpes Simplex Keratitis in an Immunocompetent Patient With Genetic Analysis of Herpes Simplex Virus 1

Cornea ◽  
2019 ◽  
Vol 38 (9) ◽  
pp. 1185-1188 ◽  
Author(s):  
Masaaki Yoshida ◽  
Mayumi Hosogai ◽  
Shunji Yokokura ◽  
Kota Sato ◽  
Takehiro Hariya ◽  
...  
Keyword(s):  
Herpes Simplex Virus ◽  
Herpes Simplex ◽  
Genetic Analysis ◽  
Immunocompetent Patient ◽  
Herpes Simplex Virus 1 ◽  
Herpes Simplex Keratitis ◽  
Simplex Virus

Lymphoproliferative and Serological Responses to Herpes Simplex Virus During Primary Infection, Recrudescence, and Re-Infection in a Murine Model

1989 ◽  
Vol 2 (2) ◽  
pp. 115-126 ◽  
Author(s):  
J.P. MAINGAY ◽  
S.E.M. HOWIE ◽  
M. NORVAL ◽  
A.M. MOODYCLIFFE ◽  
W.A. NEILL
Keyword(s):  
Herpes Simplex Virus ◽  
Herpes Simplex ◽  
Murine Model ◽  
Primary Infection ◽  
Simplex Virus

The role of the UL41 gene of herpes simplex virus type 1 in evasion of non-specific host defence mechanisms during primary infection

Microbiology ◽  
2000 ◽  
Vol 81 (7) ◽  
pp. 1763-1771 ◽  
Author(s):  
Tatsuo Suzutani ◽  
Masayoshi Nagamine ◽  
Taiichiro Shibaki ◽  
Masahiro Ogasawara ◽  
Itsuro Yoshida ◽  
...  
Keyword(s):  
Herpes Simplex Virus ◽  
Herpes Simplex ◽  
Virus Replication ◽  
Primary Infection ◽  
Interferon Α ◽  
Defence Mechanisms ◽  
Specific Host ◽  
Γ Ray ◽  
Simplex Virus

The UL41 gene product (vhs) of herpes simplex virus (HSV) is packaged in the virion, and mediates host protein synthesis shutoff at the early stage of the virus replication cycle. In order to clarify the role of vhs in virus replication and virulence, we isolated a completely UL41-deficient mutant (the VRΔ41 strain) and its revertant (the VRΔ41R strain). In the mouse encephalitis model, the replication of strain VRΔ41 was inhibited after 2 days post-infection, resulting in low virulence, by γ-ray-sensitive cells such as lymphocytes and/or neutrophils. The result suggested that some cytokines, produced in VRΔ41-inoculated brains, activate and induce the migration of γ-ray-sensitive cells to the infection site. Therefore, cytokines produced by HSV-1-infected human cells were screened, and potent inductions of interleukin (IL)-1β, IL-8 and macrophage inflammatory protein-1α by VRΔ41 infection were observed. Moreover, the VRΔ41 strain showed 20- and 5-fold higher sensitivity to interferon-α and -β compared to the wild-type strain, respectively. These results indicate that one important role of vhs in vivo is evasion from non-specific host defence mechanisms during primary infection through suppression of cytokine production in HSV-infected cells and reduction of the anti-HSV activity of interferon-α and -β.

Identification of women at unsuspected risk of primary infection with herpes simplex virus type 2 during pregnancy

1992 ◽  
Vol 39 (3) ◽  
pp. 248-248
Author(s):  
JA Kulhanjian ◽  
V Soroush ◽  
DS Au ◽  
RN Bronzan ◽  
LL Yasukawa ◽  
...  
Keyword(s):  
Herpes Simplex Virus ◽  
Herpes Simplex ◽  
Virus Type ◽  
Herpes Simplex Virus Type ◽  
Primary Infection ◽  
Simplex Virus

Latent herpes simplex virus in ganglia of mice after primary infection and reinoculation at a distant site

1978 ◽  
Vol 57 (2) ◽  
pp. 161-166 ◽  
Author(s):  
R. J. Klein ◽  
A. E. Friedman-Kien ◽  
Eileen Brady
Keyword(s):  
Herpes Simplex Virus ◽  
Herpes Simplex ◽  
Primary Infection ◽  
Distant Site ◽  
Simplex Virus
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