Tyrosine hydroxylase activity in rat brain regions after chronic treatment with ±-propranolol

1975 ◽  
Vol 27 (9) ◽  
pp. 671-676 ◽  
Author(s):  
D. A. V. PETERS ◽  
I. M. MAZURKIEWICZ-KWILECKI
1975 ◽  
Vol 93 (3) ◽  
pp. 564-569 ◽  
Author(s):  
Michel Buda ◽  
Bernard Roussel ◽  
Bernard Renaud ◽  
Jean-Fran¢ois Pujol

1982 ◽  
Vol 206 (1) ◽  
pp. 165-168 ◽  
Author(s):  
Abdulla A.-B. Badawy ◽  
David L. Williams

Rat brain catecholamine synthesis is enhanced by small doses of tyrosine, but not by doses of 50mg/kg body wt. and above. It is suggested that these latter doses overcome the above enhancement by causing a substrate inhibition of tyrosine hydroxylase activity.


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