Being Suckled in a Large Litter Mitigates the Effects of Early-Life Stress on Hypothalamic-Pituitary-Adrenal Axis Function in the Male Rat

2013 ◽  
Vol 25 (9) ◽  
pp. 792-802 ◽  
Author(s):  
M. Clarke ◽  
G. Cai ◽  
S. Saleh ◽  
K. M. Buller ◽  
S. J. Spencer
Keyword(s):  
Life Stress ◽  
Early Life ◽  
Early Life Stress ◽  
Hypothalamic Pituitary Adrenal Axis ◽  
Male Rat ◽  
Hypothalamic Pituitary Adrenal ◽  
Adrenal Axis ◽  
Large Litter ◽  
Pituitary Adrenal Axis

Early Life Stress: Long-Term Physiological Impact in Rodents and Primates

Physiology ◽  
2002 ◽  
Vol 17 (4) ◽  
pp. 150-155 ◽  
Author(s):  
Christopher R. Pryce ◽  
Daniela Rüedi-Bettschen ◽  
Andrea C. Dettling ◽  
Joram Feldon
Keyword(s):  
Life Span ◽  
Stress Responses ◽  
Life Stress ◽  
Early Life ◽  
Early Life Stress ◽  
Human Infants ◽  
Hypothalamic Pituitary Adrenal ◽  
Physiological Impact ◽  
Pituitary Adrenal Axis

Rat, monkey, and human infants have evolved to expect certain patterns of care. Spontaneous or experimental deviations of care from the norm result in infant stress responses. Hyperactivity of immature stress systems such as the limbic-hypothalamic-pituitary-adrenal axis and the limbic-sympatho-adrenomedullary axis can alter their subsequent reactivity across the life span.

scholarly journals Organizational Role for Testosterone and Estrogen on Adult Hypothalamic-Pituitary-Adrenal Axis Activity in the Male Rat

Endocrinology ◽  
2005 ◽  
Vol 146 (4) ◽  
pp. 1973-1982 ◽  
Author(s):  
J. V. Seale ◽  
S. A. Wood ◽  
H. C. Atkinson ◽  
S. L. Lightman ◽  
M. S. Harbuz
Keyword(s):  
Hypothalamic Pituitary Adrenal Axis ◽  
Male Rat ◽  
Hypothalamic Pituitary Adrenal ◽  
Organizational Role ◽  
Adrenal Axis ◽  
Pituitary Adrenal Axis
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