Vibratory testing with the 64 Hz Rydel‐Seiffer tuning fork and its relation to the sural nerve action potential

2020 ◽  
Vol 25 (4) ◽  
pp. 395-400
Author(s):  
Sophia Xirou ◽  
Panagiotis Kokotis ◽  
Thomas Zambelis ◽  
Evangelos Anagnostou
Keyword(s):  
Action Potential ◽  
Sural Nerve ◽  
Tuning Fork ◽  
Nerve Action

Effect of Interelectrode Distance on Sural Nerve Action Potential Parameters

2008 ◽  
Vol 87 (3) ◽  
pp. 183-188 ◽  
Author(s):  
Christopher T. Plastaras ◽  
Christina M. Marciniak ◽  
Daniel P. Sipple ◽  
Kirsten Gross DʼAmore ◽  
Cynthia Garvan ◽  
...  
Keyword(s):  
Action Potential ◽  
Sural Nerve ◽  
Interelectrode Distance ◽  
Nerve Action ◽  
Potential Parameters

Refractory Period of Human Sural Nerve Action Potential Related to Age in Healthy Probands

1977 ◽  
Vol 15 (2) ◽  
pp. 85-93 ◽  
Author(s):  
H.J. Lehmann ◽  
H. Muche ◽  
P. Schütt
Keyword(s):  
Action Potential ◽  
Refractory Period ◽  
Sural Nerve ◽  
Nerve Action

Lack of peripheral neuropathy in Beagle dogs after 53 weeks oral administration of thalidomide capsules

2000 ◽  
Vol 19 (11) ◽  
pp. 615-622 ◽  
Author(s):  
S Teo ◽  
M Evans ◽  
J Ehrhart ◽  
M Brockman ◽  
D Allen ◽  
...  
Keyword(s):  
Peripheral Neuropathy ◽  
Action Potential ◽  
Sural Nerve ◽  
Recovery Period ◽  
Sensory Nerve ◽  
Sensory Nerve Action Potential ◽  
Beagle Dogs ◽  
Toxicology Study ◽  
Nerve Action ◽  
Sensory Nerve Action

Thalidomide (Thalomid®) is approved for use in the US to treat complications from leprosy. Peripheral neuropathy is a dose-limiting adverse event in humans. As part of a nonrodent regulatory toxicology study, Beagle dogs were fed orally via encapsulation for 53 weeks. A component of this study was to determine if the dogs developed peripheral neuropathy. Twenty-eight male and 28 female Beagle dogs approximately 8-10 months of age were used. They were dosed at 43, 200 or 1000 mg/kg for 53 weeks followed by a 4-week treatment-free recovery period. Nerve function was assessed by electrophysiological measurements of the tibial nerve prior to dosing and at weeks 13, 27, 38 and 51. Representative dogs from each group were sacrificed at 26, 53 and 58 weeks and histologic and ultrastructural evaluations were performed on the sural nerve. Thali-domide had no effect on sensory nerve conduction velocity, duration or amplitude of the action potential. At 27 weeks, mean sensory nerve action potential amplitude for females at 43 mg/kg was significantly greater than control but was not evident at 39 weeks. Mean duration of sensory nerve action potential seemed to increase with similar magnitude over time in all dose groups including controls. Histological and ultrastructural evaluation of sections of sural nerve did not identify treatment-induced differences between control and thalidomide-dosed animals after 26 and 53 weeks of treatment. Additionally, no differences were observed following a 5-week treatment-free period at week 58. In contrast to humans, Beagle dogs did not develop thalidomide-induced peripheral neuropathy under conditions of the study.

EFFECT OF INTERELECTRODE DISTANCE ON SURAL NERVE ACTION POTENTIAL PARAMETERS

2000 ◽  
Vol 79 (2) ◽  
pp. 210-211
Author(s):  
C. T. Plastaras ◽  
K. D'Amore ◽  
C. Marciniak
Keyword(s):  
Action Potential ◽  
Sural Nerve ◽  
Interelectrode Distance ◽  
Nerve Action ◽  
Potential Parameters

scholarly journals On the psychophysical discriminability of somatosensory nerve action potential patterns with irregular intervals

1967 ◽  
Vol 2 (8) ◽  
pp. 341-348 ◽  
Author(s):  
William R. Uttal ◽  
Pamela Smith
Keyword(s):  
Action Potential ◽  
Nerve Action

scholarly journals Electrophysiological diagnosis using sensory nerve action potential for the intraforaminal and extraforaminal L5 nerve root entrapment

2012 ◽  
Vol 22 (4) ◽  
pp. 833-839 ◽  
Author(s):  
Muneharu Ando ◽  
Tetsuya Tamaki ◽  
Mamoru Kawakami ◽  
Akihito Minamide ◽  
Yukihiro Nakagawa ◽  
...  
Keyword(s):  
Action Potential ◽  
Nerve Root ◽  
Sensory Nerve ◽  
Sensory Nerve Action Potential ◽  
Nerve Action ◽  
Sensory Nerve Action ◽  
Nerve Root Entrapment

A model of the nerve action potential

1979 ◽  
Vol 46 (1-2) ◽  
pp. 11-36 ◽  
Author(s):  
Jonathan Bell ◽  
L. Pamela Cook
Keyword(s):  
Action Potential ◽  
Nerve Action
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