scholarly journals Alopecia areata after ChAdOx1 nCoV‐19 vaccine (Oxford/AstraZeneca): a potential triggering factor?

Author(s):  
Reham Essam ◽  
Rana Ehab ◽  
Radwa Al‐Razzaz ◽  
Maha W. Khater ◽  
Emad A. Moustafa
2000 ◽  
Vol 4 (2) ◽  
pp. 63-65 ◽  
Author(s):  
Annamaria Offidani ◽  
Paolo Amerio ◽  
Maria Luisa Bernardini ◽  
Claudio Feliciani ◽  
Guido Bossi

Background: Cytomegalovirus (CMV) infection has been correlated with various autoimmune disorders. Using molecular biology techniques, DNA sequences of CMV have been reported in paraffin sections of alopecia areata (AA) lesions. Reactivation of the CMV infection has been postulated as one of the pathogenic mechanisms in AA. Other studies, using different techniques however have demonstrated no correlation between CMV and AA. Objectives: This study was to clarify the role of CMV infection and to demonstrate the absence of replication of other autoimmune diseases-related herpes virus (EBV) in the pathogenesis of AA. Methods: After extraction of mRNA from tissue samples of a patient with active patchy AA, reverse transcriptase-polymerase chain reaction was carried out using primers specific for some viral members of the β-herpes viridae family (CMV, EBV, HSV). Results: No replication of the CMV or other β-herpes viridae has been detected in any of the samples collected. Conclusions: The results strongly support the hypothesis that CMV is not the triggering factor in AA, neither as a re-activator of the immune response nor as a trigger of the autoimmunity. No other herpes virus is implicated in the pathogenesis of this disease.


2015 ◽  
Vol 10 (7) ◽  
Author(s):  
Hisham Diab Gaber ◽  
Ahmed M. Mohamed ◽  
Reham M. Abdel Gaber

Author(s):  
Nikhil N. ◽  
Mamatha P. ◽  
Hanumanthayya K.

<p class="abstract"><strong>Background:</strong> Alopecia areata (AA) is a common chronic inflammatory disease causing unpredictable non scarring form of hair loss. Dermoscopy is a clear cut as well as valuable method done in a noninvasive manner to study the signs of alopecia areata. Aim was to elucidate the various clinical characteristics and dermoscopic findings of alopecia areata.</p><p class="abstract"><strong>Methods:</strong> A total of 150 patients were examined using a dermlite dermoscope at dermatovenereology OPD of Vydehi Hospital. Detailed history, clinical features, associated changes, severity and dermoscopic findings were noted.</p><p class="abstract"><strong>Results: </strong>In our study males (54.7%) were more than females (45.35%) with the ratio of 1.2:1. Mean age of the patients was 25 years. Mean duration of the disease was around 6 months. The most common type noted in our study was patchy alopecia (76%) and most common affected site was scalp (frontal and parietal region) (49.35%). 28% of the people have itching, otherwise it is mostly asymptomatic. Stress was a triggering factor in 24.70% patients. Nail changes in the form of pitting seen in 20.7% patients. The various dermoscopic findings observed in our study are yellow dots (80%), short vellus hair (74.7%), exclamation hair (34%), black dots (28%), broken hair (25.3%).</p><p class="abstract"><strong>Conclusions:</strong> Short vellus hair and yellow dots are seen in most cases of our study. They vary according to the activity of the disease and treatment. Yellow dots, black dots and tapering hair indicate active disease, while short vellus hairs indicate remission.</p><p> </p>


1978 ◽  
Vol 114 (7) ◽  
pp. 1036-1038 ◽  
Author(s):  
L. A. Daman
Keyword(s):  

1976 ◽  
Vol 112 (10) ◽  
pp. 1397-1399 ◽  
Author(s):  
D. M. Carter

Praxis ◽  
2003 ◽  
Vol 92 (19) ◽  
pp. 912-914
Author(s):  
von Mühlenen ◽  
Schaub

Ein 23-järiger Mann leidet seit Kindheit an Haarverlust mit einem fast kompletten Fehlen der Kopfhaare seit seinem sechsten Altersjahr. In den letzten Monaten war es zu einem Fortschreiten der Erkrankung mit Entwicklung einer Alopecia universalis gekommen. Wir diskutieren die Pathogenese, Differentialdiagnose und Therapie der Alopecia areata.


2013 ◽  
Author(s):  
Kristina G. Gorbatenko-Roth ◽  
Neil S. Prose ◽  
Cathy Breuer ◽  
Melisa Entinger

1995 ◽  
Vol 5 (1) ◽  
pp. 19-19
Author(s):  
Richard C. Shiell ◽  
Marc A. Pomerantz
Keyword(s):  

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