Isorhamnetin inhibits Prevotella intermedia lipopolysaccharide-induced production of interleukin-6 in murine macrophages via anti-inflammatory heme oxygenase-1 induction and inhibition of nuclear factor-κB and signal transducer and activator of transcript

2013 ◽  
Vol 48 (6) ◽  
pp. 687-695 ◽  
Author(s):  
J. Y. Jin ◽  
E. Y. Choi ◽  
H. R. Park ◽  
J. I. Choi ◽  
I. S. Choi ◽  
...  
Keyword(s):  
Heme Oxygenase ◽  
Interleukin 6 ◽  
Nuclear Factor Κb ◽  
Heme Oxygenase 1 ◽  
Prevotella Intermedia ◽  
Nuclear Factor ◽  
Signal Transducer ◽  
Murine Macrophages ◽  
Anti Inflammatory

Anti-inflammatory effect of grape seed may involve the induction of heme oxygenase-1 and suppression of nuclear factor-κB activation

2011 ◽  
Vol 20 (6) ◽  
pp. 1713-1719 ◽  
Author(s):  
Jeehye Sung ◽  
Younghwa Kim ◽  
Youngmin Choi ◽  
Hyeonmi Ham ◽  
Heon-Sang Jeong ◽  
...  
Keyword(s):  
Heme Oxygenase ◽  
Nuclear Factor Κb ◽  
Grape Seed ◽  
Heme Oxygenase 1 ◽  
Nuclear Factor ◽  
Anti Inflammatory ◽  
Inflammatory Effect

scholarly journals Role of nuclear factor-κ B and heme oxygenase-1 in the mechanism of action of an anti-inflammatory chalcone derivative in RAW 264.7 cells

2004 ◽  
Vol 142 (7) ◽  
pp. 1191-1199 ◽  
Author(s):  
María José Alcaraz ◽  
Ana María Vicente ◽  
Amparo Araico ◽  
José N Dominguez ◽  
María Carmen Terencio ◽  
...  
Keyword(s):  
Heme Oxygenase ◽  
Mechanism Of Action ◽  
Raw 264.7 Cells ◽  
Heme Oxygenase 1 ◽  
Raw 264.7 ◽  
Nuclear Factor ◽  
Chalcone Derivative ◽  
Anti Inflammatory ◽  
Nuclear Factor Κ B

6-Gingerol Ameliorates Sepsis Induced Acute Lung Injury by Regulating Nuclear Factor-κB and Nuclear-Factor Erythroid 2-Related Factor 2/Heme Oxygenase-1 Signaling Pathways

2020 ◽  
Vol 19 (3) ◽  
pp. 255-260
Author(s):  
Fan Yang ◽  
Lu Deng ◽  
MuHu Chen ◽  
Ying Liu ◽  
Jianpeng Zheng
Keyword(s):  
Acute Lung Injury ◽  
Lung Injury ◽  
Heme Oxygenase ◽  
Interleukin 1 ◽  
Nuclear Factor Κb ◽  
Heme Oxygenase 1 ◽  
Related Factor ◽  
Nuclear Factor ◽  
Alveolar Collapse ◽  
Factor Α

Acute lung injury initiated systemic inflammation leads to sepsis. Septic mice show a series of degenerative changes in lungs as demonstrated by pulmonary congestion, alveolar collapse, inflammatory cell infiltration, and increased wet-todry weight in lungs. 6-Gingerol ameliorates histopathological changes and clinical outcome of the sepsis. The increase in the levels of tumor necrosis factor-α, interleukin-1 beta, interleukin-6, and interleukin-18 in septic mice were reduced by administration with 6-Gingerol. Also, 6-Gingerol attenuates sepsis-induced increase of malonaldehyde and decrease of catalase, superoxide, and glutathione. Enhanced phospho-p65, reduced nuclear factor erythropoietin-2-related factor 2, and heme oxygenase 1 in septic mice were reversed by administration with 6-Gingerol. In conclusion, 6-Gingerol demonstrates anti-inflammatory and antioxidant effects against sepsis associated acute lung injury through inactivation of nuclear factor-kappa B and activation of nuclear-factor erythroid 2-related factor 2 pathways.

scholarly journals Anti-inflammatory effects ofSaururus chinensisaerial parts in murine macrophages via induction of heme oxygenase-1

2015 ◽  
Vol 241 (4) ◽  
pp. 396-408 ◽  
Author(s):  
Xue Meng ◽  
Inhye Kim ◽  
Yong Joon Jeong ◽  
Young Mi Cho ◽  
Se Chan Kang
Keyword(s):  
Heme Oxygenase ◽  
Heme Oxygenase 1 ◽  
Murine Macrophages ◽  
Anti Inflammatory
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