scholarly journals Prevalence of sleep disruption and determinants of sleepiness in a cohort of Italian hospital physicians: The PRESOMO study

2021 ◽  
Author(s):  
Rosamaria Lecca ◽  
Enrica Bonanni ◽  
Elvia Battaglia ◽  
Michelangelo Maestri ◽  
Michela Figorilli ◽  
...  
Keyword(s):  
Sleep Disruption ◽  
Italian Hospital ◽  
Hospital Physicians

scholarly journals Patient safety and medical errors: knowledge, attitudes and behavior among Italian hospital physicians

2012 ◽  
Vol 24 (3) ◽  
pp. 258-265 ◽  
Author(s):  
Domenico Flotta ◽  
Paolo Rizza ◽  
Aida Bianco ◽  
Claudia Pileggi ◽  
Maria Pavia
Keyword(s):  
Patient Safety ◽  
Medical Errors ◽  
Italian Hospital ◽  
Hospital Physicians ◽  
And Behavior ◽  
Attitudes And Behavior

Sleep Disruption in Detoxified Substance Abusers

2008 ◽  
Author(s):  
Rebecca J. Gilbertson ◽  
Robert A. Prather ◽  
Sara J. Nixon
Keyword(s):  
Substance Abusers ◽  
Sleep Disruption

166-LB: Participants with KATP-Related Neonatal Diabetes (KATP-NDM) Experience More Sleep Disruption than Sibling Controls

Diabetes ◽  
2020 ◽  
Vol 69 (Supplement 1) ◽  
pp. 166-LB
Author(s):  
PERSEPHONE TIAN ◽  
SAMPATH CHOPPARA ◽  
ANASTASIA HARRIS ◽  
LISA R. LETOURNEAU-FREIBERG ◽  
SIRI ATMA W. GREELEY
Keyword(s):  
Neonatal Diabetes ◽  
Sleep Disruption

Effects of Dose-Dependent Sleep Disruption on Fear and Reward Responses

2013 ◽  
Author(s):  
Anne Germain
Keyword(s):  
Sleep Disruption ◽  
Dose Dependent

Impact of reduce the sleep disruption causes at post-operative ICU among patients after open Heart

2013 ◽  
Vol 1 (1) ◽  
pp. 24-36
Author(s):  
Walaa Mohamed ◽  
Olfat El- Shafiey ◽  
Hamdy Youssef
Keyword(s):  
Sleep Disruption ◽  
Open Heart

025 Sleep Disruption on an Orbital Shaker alters Glutamate in Prairie Vole Prefrontal Cortex

SLEEP ◽  
2021 ◽  
Vol 44 (Supplement_2) ◽  
pp. A11-A12
Author(s):  
Carolyn Jones ◽  
Randall Olson ◽  
Alex Chau ◽  
Peyton Wickham ◽  
Ryan Leriche ◽  
...  
Keyword(s):  
Autism Spectrum Disorder ◽  
Prefrontal Cortex ◽  
Early Life ◽  
Autism Spectrum ◽  
Prairie Vole ◽  
Sleep Disruption ◽  
Glutamatergic Synapses ◽  
The Brain ◽  
Orbital Shaker

Abstract Introduction Glutamate concentrations in the cortex fluctuate with the sleep wake cycle in both rodents and humans. Altered glutamatergic signaling, as well as the early life onset of sleep disturbances have been implicated in neurodevelopmental disorders such as autism spectrum disorder. In order to study how sleep modulates glutamate activity in brain regions relevant to social behavior and development, we disrupted sleep in the socially monogamous prairie vole (Microtus ochrogaster) rodent species and quantified markers of glutamate neurotransmission within the prefrontal cortex, an area of the brain responsible for advanced cognition and complex social behaviors. Methods Male and female prairie voles were sleep disrupted using an orbital shaker to deliver automated gentle cage agitation at continuous intervals. Sleep was measured using EEG/EMG signals and paired with real time glutamate concentrations in the prefrontal cortex using an amperometric glutamate biosensor. This same method of sleep disruption was applied early in development (postnatal days 14–21) and the long term effects on brain development were quantified by examining glutamatergic synapses in adulthood. Results Consistent with previous research in rats, glutamate concentration in the prefrontal cortex increased during periods of wake in the prairie vole. Sleep disruption using the orbital shaker method resulted in brief cortical arousals and reduced time in REM sleep. When applied during development, early life sleep disruption resulted in long-term changes in both pre- and post-synaptic components of glutamatergic synapses in the prairie vole prefrontal cortex including increased density of immature spines. Conclusion In the prairie vole rodent model, sleep disruption on an orbital shaker produces a sleep, behavioral, and neurological phenotype that mirrors aspects of autism spectrum disorder including altered features of excitatory neurotransmission within the prefrontal cortex. Studies using this method of sleep disruption combined with real time biosensors for excitatory neurotransmitters will enhance our understanding of modifiable risk factors, such as sleep, that contribute to the altered development of glutamatergic synapses in the brain and their relationship to social behavior. Support (if any) NSF #1926818, VA CDA #IK2 BX002712, Portland VA Research Foundation, NIH NHLBI 5T32HL083808-10, VA Merit Review #I01BX001643

scholarly journals Nightmare content during the COVID‐19 pandemic: Influence of COVID‐related stress and sleep disruption in the United States

2021 ◽  
Author(s):  
Kathryn E. R. Kennedy ◽  
Célyne H. Bastien ◽  
Perrine M. Ruby ◽  
William D. S. Killgore ◽  
Chloe C. A. Wills ◽  
...  
Keyword(s):  
United States ◽  
The United States ◽  
Sleep Disruption ◽  
Related Stress
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