Fresh frozen plasma transfusion fails to influence the hemostatic balance in critically ill patients with a coagulopathy: comment

2015 ◽  
Vol 13 (10) ◽  
pp. 1941-1943 ◽  
Author(s):  
A. Tripodi ◽  
V. Chantarangkul ◽  
M. Primignani
Keyword(s):  
Critically Ill ◽  
Critically Ill Patients ◽  
Fresh Frozen Plasma ◽  
Plasma Transfusion ◽  
Fresh Frozen ◽  
Frozen Plasma

Fresh frozen plasma transfusion in critically ill patients*

2007 ◽  
Vol 35 (7) ◽  
pp. 1655-1659 ◽  
Author(s):  
François Lauzier ◽  
Deborah Cook ◽  
Lauren Griffith ◽  
Julia Upton ◽  
Mark Crowther
Keyword(s):  
Critically Ill ◽  
Critically Ill Patients ◽  
Fresh Frozen Plasma ◽  
Plasma Transfusion ◽  
Fresh Frozen ◽  
Frozen Plasma

Fresh frozen plasma transfusion fails to influence the hemostatic balance in critically ill patients with a coagulopathy

2015 ◽  
Vol 13 (6) ◽  
pp. 989-997 ◽  
Author(s):  
M. C. A. Müller ◽  
M. Straat ◽  
J. C. M. Meijers ◽  
J. H. Klinkspoor ◽  
E. de Jonge ◽  
...  
Keyword(s):  
Critically Ill ◽  
Critically Ill Patients ◽  
Fresh Frozen Plasma ◽  
Plasma Transfusion ◽  
Fresh Frozen ◽  
Frozen Plasma

A national clinical scenario-based survey of clinicians' attitudes towards fresh frozen plasma transfusion for critically ill patients

2010 ◽  
Vol 21 (2) ◽  
pp. 124-129 ◽  
Author(s):  
D. M. Watson ◽  
S. J. Stanworth ◽  
D. Wyncoll ◽  
D. F. McAuley ◽  
G. D. Perkins ◽  
...  
Keyword(s):  
Critically Ill ◽  
Critically Ill Patients ◽  
Fresh Frozen Plasma ◽  
Clinical Scenario ◽  
Plasma Transfusion ◽  
Fresh Frozen ◽  
Frozen Plasma

Fresh frozen plasma transfusion in critically ill medical patients with coagulopathy*

2005 ◽  
Vol 33 (11) ◽  
pp. 2667-2671 ◽  
Author(s):  
Saqib I. Dara ◽  
Rimki Rana ◽  
Bekele Afessa ◽  
S Breanndan Moore ◽  
Ognjen Gajic
Keyword(s):  
Critically Ill ◽  
Fresh Frozen Plasma ◽  
Medical Patients ◽  
Plasma Transfusion ◽  
Fresh Frozen ◽  
Frozen Plasma

scholarly journals Transfusion of Fresh Frozen Plasma in Critically Ill Patients: Effective or Useless?

2018 ◽  
Vol 6 (5) ◽  
pp. 820-823 ◽  
Author(s):  
Ermira Biu ◽  
Silvana Beraj ◽  
Gentian Vyshka ◽  
Lordian Nunci ◽  
Tatjana Ҫina
Keyword(s):  
Intensive Care ◽  
Critically Ill ◽  
Critically Ill Patients ◽  
Care Service ◽  
Coagulation Factors ◽  
Fresh Frozen Plasma ◽  
Minor Bleeding ◽  
Significant Difference ◽  
Fresh Frozen ◽  
Frozen Plasma

BACKGROUND: Fresh frozen plasma (FFP) is widely used in critically ill patients to correct the deficiency of coagulation factors or increased INR.AIM: In the present study we aimed to evaluate the outcome of the freshly frozen plasma use as prophylaxis in ICU patients before an invasive procedure.METHODS: The study was conducted at Central Anaesthesiology and Intensive Care Service UHCT “Mother Theresa”, Tirana. 136 patients were enrolled with coagulopathy with no bleeding before the invasive procedure, from June 2016 to December 2016. A group of 75 patients underwent a median volume of 12.5 ml/kg FFP given, and 61 had no transfusion. Data were collected on demographics, the severity of illness measured by APACHE III scores, INR, medication use, hemodynamic data.RESULTS: From 136 patients with coagulopathy with no bleeding who underwent planned invasive interventions, 75 [55%] received FFP, vs 61 [45%] p = 0.04 who did not receive. Overall, the median FFP dose was 12.5 ml kg-1. Median INR level in FFP and non-FFP groups was respectively 3.1 (1.9-4.8) and 3.5 (1.8-5.2). INR was corrected in 24 of 75 (32%) of those who received a transfusion. The frequency of minor bleeding episodes was 9.3% in transfused patients vs 4.9% in the non-transfused group. Patients who developed an onset of acute lung injury were more frequent in the FFP group. No allergic transfusion complications were observed. Also, the median length of hospital stay [LOS] was 3.05 days vs 2.91 days and mortality rate 8.2% vs 6.5% with no significant difference between two groups.CONCLUSIONS: Freshly frozen plasma transfusions are often unnecessarily administered during an inadequate correction of the deficiencies of coagulation factors. When comparing a liberal FFP transfusion strategy vs restrictive other clinical trials are required to asses which one is the best to adopt in intensive care settings.

FRESH FROZEN PLASMA TRANSFUSION IN THE CRITICALLY ILL.

2006 ◽  
Vol 34 ◽  
pp. A10
Author(s):  
Francois Lauzier ◽  
Deborah J Cook ◽  
Mark A Crowther ◽  
Lauren Griffith ◽  
Julia Upton
Keyword(s):  
Critically Ill ◽  
Fresh Frozen Plasma ◽  
Plasma Transfusion ◽  
Fresh Frozen ◽  
Frozen Plasma
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