Mechanisms underlying the adaptive pulp and jaw bone trabecular changes in sickle cell anemia

Oral Diseases ◽  
2021 ◽  
Author(s):  
Susilena Arouche Costa ◽  
Cecília Cláudia Costa Ribeiro ◽  
Erika Bárbara Abreu Fonseca Thomaz ◽  
Cyrene Piazera Silva Costa ◽  
Soraia de Fátima Carvalho Souza

Author(s):  
Mehak Khanna ◽  
Disha Prabhu

Patients suffering from haemoglobinopathies most commonly show bone infection as a complication, of which Sickle cell anaemia (SCA) patients are the most susceptible to osteomyelitis. There are very few documented cases of jaw bone osteomyelitis in SCA patients. Keeping in mind the number of children diagnosed with SCA in India, this article reports how a commonly available and non-invasive radiographic method, dental CBCT, can be used to timely diagnose jaw bone osteomyelitis. Key Words : Sickle Cell Anemia ,Chronic Osteomyelitis , Jaw , Mandible , Case Report India , Sickle Cell Anemia complications , Radiograph , CBCT , Third molar pain , Onion skin appearance , Punched out lesions



Author(s):  
Christopher A. Miller ◽  
Bridget Carragher ◽  
William A. McDade ◽  
Robert Josephs

Highly ordered bundles of deoxyhemoglobin S (HbS) fibers, termed fascicles, are intermediates in the high pH crystallization pathway of HbS. These fibers consist of 7 Wishner-Love double strands in a helical configuration. Since each double strand has a polarity, the odd number of double strands in the fiber imparts a net polarity to the structure. HbS crystals have a unit cell containing two double strands, one of each polarity, resulting in a net polarity of zero. Therefore a rearrangement of the double strands must occur to form a non-polar crystal from the polar fibers. To determine the role of fascicles as an intermediate in the crystallization pathway it is important to understand the relative orientation of fibers within fascicles. Furthermore, an understanding of fascicle structure may have implications for the design of potential sickling inhibitors, since it is bundles of fibers which cause the red cell distortion responsible for the vaso-occlusive complications characteristic of sickle cell anemia.



2007 ◽  
Vol 41 (3) ◽  
pp. 59
Author(s):  
BRUCE WILSON




2005 ◽  
Vol 11 ◽  
pp. 85
Author(s):  
Allison Elise Kerr ◽  
Wolali Odonkor ◽  
Gail Nunlee-Bland ◽  
Juanita Archer ◽  
Anitha Kolukula ◽  
...  


1974 ◽  
Vol 133 (4) ◽  
pp. 595-606 ◽  
Author(s):  
D. L. Rucknagel


1974 ◽  
Vol 133 (4) ◽  
pp. 529-532 ◽  
Author(s):  
L. S. Lessin


1974 ◽  
Vol 133 (4) ◽  
pp. 690-694 ◽  
Author(s):  
G. R. Serjeant


2020 ◽  
Author(s):  
Dorra Dorraelguiche ◽  
Manel Jemel ◽  
Grassa Anis ◽  
Hajer Kandara ◽  
Ines Kammoun


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