Sugammadex for reversal of neuromuscular blockade in pediatric patients: results from a phase IV randomized study

2021 ◽  
Author(s):  
Tiffini Voss ◽  
Aobo Wang ◽  
Matthew DeAngelis ◽  
Marcel Speek ◽  
Vera Saldien ◽  
...  
Keyword(s):  
Neuromuscular Blockade ◽  
Pediatric Patients ◽  
Randomized Study ◽  
Phase Iv

EVALUATION OF VECURONIUM NEUROMUSCULAR BLOCKADE IN PEDIATRIC PATIENTS WITH THERMAL INJURY

1987 ◽  
Vol 66 (Supplement) ◽  
pp. S119
Author(s):  
A. Mills ◽  
J. A.J. Martyn
Keyword(s):  
Neuromuscular Blockade ◽  
Thermal Injury ◽  
Pediatric Patients

scholarly journals Comparative efficacy of IV phenytoin, IV valproate and IV levetiracetam in childhood seizures

2019 ◽  
Vol 6 (4) ◽  
pp. 1592
Author(s):  
Sheeraz A. Dar ◽  
Wasim A. Wani ◽  
Mudasir Nazir ◽  
Zul Eidain Hussan
Keyword(s):  
Pediatric Patients ◽  
Seizure Control ◽  
Randomized Study ◽  
P Value ◽  
Age Group ◽  
Seizure Recurrence ◽  
Comparative Efficacy ◽  
Acute Setting ◽  
Neurologic Disorder

Background: Seizures are the most common pediatric neurologic disorder, with 4% to 10% of children suffering at least one seizure in the first 16 years of life objectives to compare efficacy of IV phenytoin, IV valproate, and IV levetiracetam in childhood seizures between 2months to 16 years of age.Methods: This prospective, randomized, study was done on pediatric patients in the age group of 2 months to 16 years who present actively convulsing to the emergency department of pediatrics.Results: At 24 hours seizures were controlled in 44 (88%) patients out of 50 patients in phenytoin group, 39 (78%) out of 50 patients in levetiracetam group and 46 (92%) out of 50 patients in valproate group (p-value 0.115). The relative risk of seizure recurrence for levetiracetam and phenytoin groups when compared to valproate was 2.75 and 1.5, respectively.Conclusions: Present study demonstrates that IV levetiracetam and IV valproate were comparable to IV phenytoin in terms of seizure control in acute setting. All the three are safe and efficacious. Time to regain consciousness was less in valproate group and long-term seizure control too was also better.

scholarly journals Two formulations of epoprostenol sodium in the treatment of pulmonary arterial hypertension: EPITOME-1 (epoprostenol for injection in pulmonary arterial hypertension), a phase IV, open-label, randomized study

2014 ◽  
Vol 167 (2) ◽  
pp. 218-225.e1 ◽  
Author(s):  
Kelly M. Chin ◽  
David B. Badesch ◽  
Ivan M. Robbins ◽  
Victor F. Tapson ◽  
Harold I. Palevsky ◽  
...  
Keyword(s):  
Pulmonary Arterial Hypertension ◽  
Arterial Hypertension ◽  
Randomized Study ◽  
Open Label ◽  
Pulmonary Arterial ◽  
Phase Iv

scholarly journals Immunogenicity and safety of the diphtheria, pertussis, tetanus and inactivated poliovirus vaccine when co-administered with the human rotavirus vaccine (Rotarix) in healthy Japanese infants: a phase IV randomized study

2019 ◽  
Vol 15 (4) ◽  
pp. 800-808
Author(s):  
Paul Gillard ◽  
Tsuyoshi Tamura ◽  
Haruo Kuroki ◽  
Yoshiyuki Morikawa ◽  
Leentje Moerman ◽  
...  
Keyword(s):  
Randomized Study ◽  
Rotavirus Vaccine ◽  
Human Rotavirus ◽  
Japanese Infants ◽  
Phase Iv

scholarly journals Immunogenicity and safety of a trivalent inactivated influenza vaccine produced in Shenzhen, China versus a comparator influenza vaccine: a phase IV randomized study

2019 ◽  
Vol 15 (5) ◽  
pp. 1066-1069
Author(s):  
Yuemei Hu ◽  
Kai Chu ◽  
Nathalie Lavis ◽  
Xiaoling Li ◽  
Bill Liang ◽  
...  
Keyword(s):  
Influenza Vaccine ◽  
Randomized Study ◽  
Phase Iv

scholarly journals A Randomized Study of Safety and Efficacy of Two Doses of Ambrisentan to Treat Pulmonary Arterial Hypertension in Pediatric Patients Aged 8 Years up to 18 Years

2020 ◽  
Vol 5 ◽  
pp. 100055
Author(s):  
Dunbar Ivy ◽  
Maurice Beghetti ◽  
Ernesto Juaneda-Simian ◽  
Diane Miller ◽  
Mary Ann Lukas ◽  
...  
Keyword(s):  
Pulmonary Arterial Hypertension ◽  
Arterial Hypertension ◽  
Pediatric Patients ◽  
Randomized Study ◽  
Safety And Efficacy ◽  
Pulmonary Arterial

NEUROMUSCULAR BLOCKADE MONITORING IN PEDIATRIC PATIENTS

2000 ◽  
Vol 100 (12) ◽  
pp. 24HH
Author(s):  
&NA;
Keyword(s):  
Neuromuscular Blockade ◽  
Pediatric Patients
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