Hemophagocytic lymphohistiocytosis induced by Toxoplasma gondii infection diagnosed by a bone marrow biopsy and DNA next generation sequencing in an allogeneic hematopoietic stem cell transplant recipient.

Author(s):  
Karam M. Obeid ◽  
Bartosz Grzywacz ◽  
Patricia Ferrieri ◽  
Sophie Arbefeville ◽  
Arne Slungaard ◽  
...  
2018 ◽  
Vol 5 (12) ◽  
Author(s):  
Monica Fung ◽  
Simona Zompi ◽  
Hon Seng ◽  
Desiree Hollemon ◽  
Adama Parham ◽  
...  

Abstract Allogeneic hematopoietic stem cell transplant patients are at risk for common and atypical infections. Superior diagnostics can decrease infection-related morbidity and mortality. A novel plasma cell–free DNA next-generation sequencing test detected an uncommon presentation of Chlamydia trachomatis and recurrent and metastatic complications of Staphylococcus aureus bacteremia before standard microbiology.


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