How platelet transfusions were invented

Transfusion ◽  
2021 ◽  
Vol 61 (12) ◽  
pp. 3483-3486
Author(s):  
Richard H. Aster
Keyword(s):  
Platelet Transfusions

scholarly journals Insertion of central venous catheters in children undergoing bone marrow transplantation: is there a platelet level for a safe procedure?

2020 ◽  
Vol 16 (1) ◽  
Author(s):  
Ahmed Elgendy ◽  
Ahmed M. Ismail ◽  
Eslam Elhawary ◽  
Ahmed Badran ◽  
Mohammed Ramadan El-Shanshory
Keyword(s):  
Bone Marrow ◽  
Platelet Count ◽  
Bone Marrow Transplantation ◽  
Postoperative Complications ◽  
Marrow Transplantation ◽  
Central Venous Catheters ◽  
Bleeding Complications ◽  
Safe Procedure ◽  
Central Venous ◽  
Platelet Transfusions

Abstract Background Bone marrow transplantation (BMT) is a therapeutic procedure for the management of several hematological diseases and malignancies in pediatric population. Central venous catheters (CVCs) play a pivotal role during the process of BMT. The aim of this study was to compare the complications of CVCs placements in children undergoing BMT with platelet levels above and below 50,000/μL and also to detect if there is a platelet count for a safe insertion. This prospective study included all children who had placements of tunneled CVCs during BMT at our hospital between March 2017 and March 2020. Procedures were divided into two groups accordingly to preoperative platelet counts (above and below 50,000/μL). Data were compared between both groups regarding postoperative complications including bleeding or catheter-related blood stream infections (CRBSIs). Results Forty-six CVC insertions were performed in 40 patients. There were 20 procedures below 50,000/μL (median 27,500; range 5000–42,000) inserted with perioperative platelet transfusions, and their postoperative levels were median 59,500/μL, range 18,000–88,000. Allogeneic BMT was adopted in 39 patients (97.5%). Beta thalassemia major was the commonest indication (21/40, 52.5%), followed by acute lymphocytic leukemia in six patients (15%). There were nine postoperative complications (bleeding n = 2 and CRBSIs n = 7) encountered in all placements. Four of them occurred in insertions below 50,000/μL (two bleeding complications that managed conservatively, and two CRBSIs). Post-procedural morbidities regarding bleeding or CRBSIs did not differ significantly between both groups (p value = 0.099 and 0.695, respectively). Conclusions Postponement of CVC insertions in thrombocytopenic children due to the fear of potential complications seems unwarranted, as it has no significant impact on the morbidity. Placements of such catheters can be safe under cover of perioperative platelet transfusions irrespective of the preoperative platelet count.

scholarly journals Expected individual benefit of prophylactic platelet transfusions in hemato‐oncology patients based on bleeding risks

Transfusion ◽  
2021 ◽  
Author(s):  
Loes L. Cornelissen ◽  
Camila Caram‐Deelder ◽  
Susanna F. Fustolo‐Gunnink ◽  
Rolf H. H. Groenwold ◽  
Simon J. Stanworth ◽  
...  
Keyword(s):  
Oncology Patients ◽  
Platelet Transfusions

Impact of Packed Red Blood Cell and Platelet Transfusions in Patients Undergoing Dissection Repair

2018 ◽  
Vol 232 ◽  
pp. 338-345 ◽  
Author(s):  
Syed S. Naeem ◽  
Neel R. Sodha ◽  
Frank W. Sellke ◽  
Afshin Ehsan
Keyword(s):  
Blood Cell ◽  
Red Blood Cell ◽  
Platelet Transfusions

Platelet Crossmatching: A Direct Approach to the Selection of Platelet Transfusions for the Alloimmunized Thrombocytopenic Patient

1988 ◽  
Vol 90 (1) ◽  
pp. 69-72 ◽  
Author(s):  
Thomas S. Kickler ◽  
Paul M. Ness ◽  
Hayden G. Braine
Keyword(s):  
Direct Approach ◽  
Thrombocytopenic Patient ◽  
Selection Of ◽  
Platelet Transfusions
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