scholarly journals A systematic review to identify whether perfusate biomarkers produced during hypothermic machine perfusion can predict graft outcomes in kidney transplantation

2020 ◽  
Vol 33 (6) ◽  
pp. 590-602 ◽  
Author(s):  
Francesco Guzzi ◽  
Simon R. Knight ◽  
Rutger J. Ploeg ◽  
James P. Hunter
Keyword(s):  
Systematic Review ◽  
Kidney Transplantation ◽  
Machine Perfusion ◽  
Hypothermic Machine Perfusion

Hypothermic machine perfusion in deceased donor kidney transplantation: a systematic review

2013 ◽  
Vol 180 (1) ◽  
pp. 176-182 ◽  
Author(s):  
Vincent W.T. Lam ◽  
Jerome M. Laurence ◽  
Arthur J. Richardson ◽  
Henry C.C. Pleass ◽  
Richard D.M. Allen
Keyword(s):  
Systematic Review ◽  
Kidney Transplantation ◽  
Deceased Donor ◽  
Machine Perfusion ◽  
Donor Kidney ◽  
Hypothermic Machine Perfusion ◽  
Deceased Donor Kidney ◽  
Donor Kidney Transplantation ◽  
Deceased Donor Kidney Transplantation

scholarly journals Optimizing porcine donor kidney preservation with normothermic or hypothermic machine perfusion: A systematic review

2021 ◽  
Author(s):  
Sarah Bouari ◽  
Özgür Eryigit ◽  
Ron W. F. Bruin ◽  
Jan N. M. IJzermans ◽  
Robert C. Minnee
Keyword(s):  
Systematic Review ◽  
Machine Perfusion ◽  
Donor Kidney ◽  
Kidney Preservation ◽  
Hypothermic Machine Perfusion

Combined Heart and Kidney Transplantation: How Hypothermic Machine Perfusion Enables Delayed Kidney Implantation

2021 ◽  
Author(s):  
S. Lukas ◽  
C. Bogensperger ◽  
H. Antretter ◽  
M. Grimm ◽  
S. Schneeberger ◽  
...  
Keyword(s):  
Kidney Transplantation ◽  
Machine Perfusion ◽  
Hypothermic Machine Perfusion

Hypothermic Machine Perfusion in DCD Kidney Transplantation: A Single Center Experience

2015 ◽  
Vol 96 (2) ◽  
pp. 148-151 ◽  
Author(s):  
Liyu Yao ◽  
Honglan Zhou ◽  
Yuantao Wang ◽  
Gang Wang ◽  
Weigang Wang ◽  
...  
Keyword(s):  
Kidney Transplantation ◽  
Graft Function ◽  
Postoperative Recovery ◽  
Donation After Cardiac Death ◽  
Machine Perfusion ◽  
Transplant Recipients ◽  
Kidney Transplant Recipients ◽  
Single Center Experience ◽  
Hypothermic Machine Perfusion ◽  
Significant Difference

Introduction: Donation after cardiac death (DCD) began in 2011 after the program hosted by the First Affiliated Hospital of Sun Yat-sen University in China. The aim of this study is to report on our experience regarding the method of preserving donated kidneys for DCD kidney transplantation. Material and Methods: A total of 37 donors and 73 primary kidney transplant recipients during the period 2011-2014 in the Urology Center of the First Hospital of Jilin University were enrolled in the study. Recipients were assigned to traditional static cold storage (SCS) group and hypothermic machine perfusion (HMP) group based on the preservation environment of donated kidneys after organ harvest. Clinical data were collected for each group. Result: The HMP group had a lower rate of delayed graft function (DGF), better postoperative recovery and kidney function compared with that of SCS group. There is no significant difference in postoperative rejection incidence between the 2 groups. Conclusions: DCD kidneys stored by hypothermic machine contribute to a lower rate of DGF and promoted the rehabilitation progress.

scholarly journals A Retrospective Propensity Score Matched Analysis Reveals Superiority of Hypothermic Machine Perfusion over Static Cold Storage in Deceased Donor Kidney Transplantation

2020 ◽  
Vol 9 (7) ◽  
pp. 2311
Author(s):  
Silvia Gasteiger ◽  
Valeria Berchtold ◽  
Claudia Bösmüller ◽  
Lucie Dostal ◽  
Hanno Ulmer ◽  
...  
Keyword(s):  
Kidney Transplantation ◽  
Propensity Score ◽  
Graft Survival ◽  
Cold Storage ◽  
Strong Predictor ◽  
Graft Function ◽  
Machine Perfusion ◽  
Hypothermic Machine Perfusion ◽  
Increased Risk ◽  
Matching Criteria

Hypothermic machine perfusion (HMP) has been introduced as an alternative to static cold storage (SCS) in kidney transplantation, but its true benefit in the clinical routine remains incompletely understood. The aim of this study was to assess the effect of HMP vs. SCS in kidney transplantation. All kidney transplants performed between 08/2015 and 12/2019 (n = 347) were propensity score (PS) matched for cold ischemia time (CIT), extended criteria donor (ECD), gender mismatch, cytomegalovirus (CMV) mismatch, re-transplantation and Eurotransplant (ET) senior program. A total of 103 HMP and 103 SCS instances fitted the matching criteria. Prior to PS matching, the CIT was longer in the HMP group (17.5 h vs. 13.3 h; p < 0.001), while the delayed graft function (DGF) rates were 29.8% and 32.3% in HMP and SCS, respectively. In the PS matched groups, the DGF rate was 64.1% in SCS vs. 31.1% following HMP: equivalent to a 51.5% reduction of the DGF rate (OR 0.485, 95% CI 0.318–0.740). DGF was associated with decreased 1- and 3-year graft survival (100% and 96.3% vs. 90.8% and 86.7%, p = 0.001 and p = 0.008) or a 4.1-fold increased risk of graft failure (HR = 4.108; 95% CI: 1.336–12.631; p = 0.014). HMP significantly reduces DGF in kidney transplantation. DGF remains a strong predictor of graft survival.

Hypothermic machine perfusion in kidney transplantation

2016 ◽  
Vol 21 (3) ◽  
pp. 294-300 ◽  
Author(s):  
Julie De Deken ◽  
Peri Kocabayoglu ◽  
Cyril Moers
Keyword(s):  
Kidney Transplantation ◽  
Machine Perfusion ◽  
Hypothermic Machine Perfusion

Effectivity of Hypothermic Machine Perfusion Preservation for Non-Heart-Beating Donor Kidney Transplantation in Japan

2018 ◽  
Vol 102 ◽  
pp. S790
Author(s):  
Naotake Akutsu ◽  
Michihiro Maruyama ◽  
Kazunori Otsuki ◽  
Kenichi Saigo ◽  
Hiromichi Aoyama ◽  
...  
Keyword(s):  
Kidney Transplantation ◽  
Machine Perfusion ◽  
Donor Kidney ◽  
Hypothermic Machine Perfusion ◽  
Heart Beating ◽  
Donor Kidney Transplantation
Sign in / Sign up

Export Citation Format

Share Document