Enhancing Video Capsule Endoscopy: Location and Bleeding Detection

Author(s):  
Douglas Yeung ◽  
Amir Sabet Sarvestani ◽  
Jonathan Yap ◽  
Yuri Inoue

Video capsule endoscopy (VCE) is a non-invasive method of visually examining the internal lumen of small intestine for inflammation and bleeding through a wireless camera contained in a small capsule. Currently, VCE technology is limited because it cannot map images to their specific locations in the small bowel. Furthermore, approximately 40% of identified problem areas are false positives, making bleeding difficult to find. Therefore, physicians can only estimate the location of inflammation and bleeding areas based on the elapsed time before performing a wired endoscopy. Our pill camera offers an innovative wireless imaging GPS-like location system, in an easy to swallow pill that accurately identifies and displays bleeding areas within the small intestine through an intuitive user interface, which results in a 50% reduction in clinical times, as well as improved diagnosis for potential investors and providers, thus resulting in a $500 cost reduction in physician fees per patient.

2017 ◽  
Author(s):  
Neil Marya ◽  
Veronica Baptista ◽  
Anupam Singh ◽  
Joseph Charpentier ◽  
David Cave

Until 2001, the nonsurgical evaluation of the small intestine was largely limited to the use of radiologic imaging (e.g., small bowel follow-through or enteroclysis). With the now widespread availability of video capsule endoscopy and deep enteroscopy since 2001, we are now able to visualize the length and most of the mucosa of the small intestine and manage small bowel lesions that were previously inaccessible except by surgical intervention. This review serves as an overview for these two procedures, detailing the indications and contraindications, proper timing of the procedure, technical aspects of the devices themselves, possible complications, and outcomes. Figures show endoscopic images that demonstrate multiple angioectasias, bleeding during capsule endoscopy, active Crohn disease of the small bowel, severe mucosal scalloping, small bowel carcinoid tumor, small bowel polyp associated with Peutz-Jeghers syndrome, and nonsteroidal antiinflammatory drug enteropathy; serial x-rays of a patient with a patency capsule retained inside the small intestine; a computer image showing the distribution of small bowel tumors; and a pie chart displaying the breakdown of the distribution of benign and malignant tumors that can be found in the small intestine. Videos show multiple angioectasias, bleeding during capsule endoscopy, active Crohn disease of the small bowel, small bowel carcinoid tumor, and small bowel polyp associated with Peutz-Jeghers syndrome. This review contains 10 highly rendered figures, 5 videos, and 50 references.


2020 ◽  
Vol 15 (1) ◽  
pp. 65-68 ◽  
Author(s):  
Francesco Abbruzzi ◽  
Ilaria Loconte ◽  
Sonia Carparelli ◽  
Enzo Ierardi ◽  
Alfredo Di Leo ◽  
...  

Background: Olmesartan, an antihypertensive drug, may be associated with a severe “sprue-like enteropathy”. Objectives: To report a case of Olmesartan enteropathy demonstrated by video capsule endoscopy distally from the second duodenum along with the whole small bowel before and after drug withdrawal. Case Presentation: A 81-years-old man was referred for asthenia, chronic watery diarrhea and anasarca (ascites, pleural effusion and edemas of superior and inferior limb). The only comorbidity was hypertension treated with Olmesartan. All causes of infective and inflammatory chronic diarrhea were investigated and excluded. Upper endoscopy was normal; histological examination of the second portion of the duodenum showed moderate and patchy infiltration of lymphocytes at mucosal and intra-epithelial level with intermittent partial villous atrophy. The possibility of adverse drug reaction, estimated by Naranjo scale, showed a score of 7, indicating a strong probability. Olmesartan was then withdrawn. However, because of severe clinical general condition, we preferred to corroborate our diagnostic work-up by a non-invasive investigation, i.e. video capsule endoscopy, which showed jejunal and ileal mucosal alterations (mosaic pattern, diffuse hyperemia, severe edema, consequent apparent reduced lumen, diffuse thickening of intestinal folds, multiple erosions, patchy lymphangectasia). After 14 days, the resolution of anasarcatic state and hydroelectrolytic imbalances was observed. Nine months later, small-bowel video-capsule demonstrated mild mucosal hyperaemia and mosaic pattern. Conclusions: Our case could give new insights in the field of Olmesartan associated enteropathy by highlighting the possibility of distally main lesion location and, therefore, the usefulness of video capsule endoscopy in the presence of doubtful diagnostic features.


2010 ◽  
Vol 4 (2) ◽  
Author(s):  
Yurika Inoue ◽  
Amir Sabet Sarvestani ◽  
Jonathan Yap ◽  
Douglas L. Yeung

Video capsule endoscopy (VCE) is a method used to wirelessly scan the gastrointestinal (GI) tract lumen. Despite the effectiveness of VCE in GI endoscopic procedures, VCE is limited because it lacks the capability to exactly locate itself as well as accurately detect bleeding or clotting within the GI tract. The unreliability of localization combined with inaccurate blood detection in VCE ultimately leads to wired endoscopy for additional diagnosis. In this paper, a method to address localization of the VCE device, also known as a pill camera or capsule, in conjunction with an accurate detection of active bleeding and clotting inside the small intestine, is introduced. The Texas Instruments, ZigBee® kit, which uses a 3D trilateration method will be used for accurate location detection and image transmission throughout the VCE procedure. The system will be interfaced with software providing end users with the path and total distance traveled by the pill capsule within the small intestine. The blood detection system is enhanced by using a minilow energy wireless Raman spectrometry to scan for active bleeding or clots along the small intestinal wall. The employed spectrometry method scans for wavelengths based on blood’s optical characteristics and records any image fitting the exact spectrum. Blood detection and localization data are coupled together and then transferred to an external receiver. These two improvements together will enhance capsule endoscopy procedures and fill the gap created by the existing capsule endoscopy technologies, therefore, meeting the needs of physicians and patients.


2012 ◽  
Vol 03 (S 05) ◽  
pp. 071-073
Author(s):  
Samuel N. Adler

AbstractIn this article the brief and dramatic history of capsule endoscopy of the digestive tract is reviewed. Capsule endoscopy offers a non invasive method to diagnose diseases that affect the esophagus, small bowel and colon. Technological improvements relating to optics, software, data recorders with two way communication have revolutionized this field. These advancements have produced better diagnostic performance.


2015 ◽  
Author(s):  
Neil Marya ◽  
Veronica Baptista ◽  
Anupam Singh ◽  
Joseph Charpentier ◽  
David Cave

Until 2001, the nonsurgical evaluation of the small intestine was largely limited to the use of radiologic imaging (e.g., small bowel follow-through or enteroclysis). With the now widespread availability of video capsule endoscopy and deep enteroscopy since 2001, we are now able to visualize the length and most of the mucosa of the small intestine and manage small bowel lesions that were previously inaccessible except by surgical intervention. This review serves as an overview for these two procedures, detailing the indications and contraindications, proper timing of the procedure, technical aspects of the devices themselves, possible complications, and outcomes. Figures show endoscopic images that demonstrate multiple angioectasias, bleeding during capsule endoscopy, active Crohn disease of the small bowel, severe mucosal scalloping, small bowel carcinoid tumor, small bowel polyp associated with Peutz-Jeghers syndrome, and nonsteroidal antiinflammatory drug enteropathy; serial x-rays of a patient with a patency capsule retained inside the small intestine; a computer image showing the distribution of small bowel tumors; and a pie chart displaying the breakdown of the distribution of benign and malignant tumors that can be found in the small intestine. Videos show multiple angioectasias, bleeding during capsule endoscopy, active Crohn disease of the small bowel, small bowel carcinoid tumor, and small bowel polyp associated with Peutz-Jeghers syndrome. This review contains 10 highly rendered figures, 5 videos, and 50 references.


2021 ◽  
Vol 93 (6) ◽  
pp. AB352-AB353
Author(s):  
Angel N. Del Cueto-Aguilera ◽  
Diego Garcia-Compean ◽  
Jose A. Gonzalez ◽  
Joel O. Jaquez-Quintana ◽  
Omar D. Borjas-Almaguer ◽  
...  

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