scholarly journals Enhancing Video Capsule Endoscopy: Location and Bleeding Detection

2010 ◽  
Vol 4 (2) ◽  
Author(s):  
Yurika Inoue ◽  
Amir Sabet Sarvestani ◽  
Jonathan Yap ◽  
Douglas L. Yeung
Keyword(s):  
Small Intestine ◽  
Capsule Endoscopy ◽  
Detection System ◽  
Image Transmission ◽  
Intestinal Wall ◽  
Active Bleeding ◽  
Video Capsule Endoscopy ◽  
Gi Tract ◽  
Raman Spectrometry ◽  
Bleeding Detection

Video capsule endoscopy (VCE) is a method used to wirelessly scan the gastrointestinal (GI) tract lumen. Despite the effectiveness of VCE in GI endoscopic procedures, VCE is limited because it lacks the capability to exactly locate itself as well as accurately detect bleeding or clotting within the GI tract. The unreliability of localization combined with inaccurate blood detection in VCE ultimately leads to wired endoscopy for additional diagnosis. In this paper, a method to address localization of the VCE device, also known as a pill camera or capsule, in conjunction with an accurate detection of active bleeding and clotting inside the small intestine, is introduced. The Texas Instruments, ZigBee® kit, which uses a 3D trilateration method will be used for accurate location detection and image transmission throughout the VCE procedure. The system will be interfaced with software providing end users with the path and total distance traveled by the pill capsule within the small intestine. The blood detection system is enhanced by using a minilow energy wireless Raman spectrometry to scan for active bleeding or clots along the small intestinal wall. The employed spectrometry method scans for wavelengths based on blood’s optical characteristics and records any image fitting the exact spectrum. Blood detection and localization data are coupled together and then transferred to an external receiver. These two improvements together will enhance capsule endoscopy procedures and fill the gap created by the existing capsule endoscopy technologies, therefore, meeting the needs of physicians and patients.

Enhancing Video Capsule Endoscopy: Location and Bleeding Detection

2010 ◽  
Author(s):  
Douglas Yeung ◽  
Amir Sabet Sarvestani ◽  
Jonathan Yap ◽  
Yuri Inoue
Keyword(s):  
Small Intestine ◽  
Small Bowel ◽  
Capsule Endoscopy ◽  
Cost Reduction ◽  
Video Capsule Endoscopy ◽  
Non Invasive ◽  
Elapsed Time ◽  
Bleeding Detection ◽  
Invasive Method ◽  
Intuitive User Interface

Video capsule endoscopy (VCE) is a non-invasive method of visually examining the internal lumen of small intestine for inflammation and bleeding through a wireless camera contained in a small capsule. Currently, VCE technology is limited because it cannot map images to their specific locations in the small bowel. Furthermore, approximately 40% of identified problem areas are false positives, making bleeding difficult to find. Therefore, physicians can only estimate the location of inflammation and bleeding areas based on the elapsed time before performing a wired endoscopy. Our pill camera offers an innovative wireless imaging GPS-like location system, in an easy to swallow pill that accurately identifies and displays bleeding areas within the small intestine through an intuitive user interface, which results in a 50% reduction in clinical times, as well as improved diagnosis for potential investors and providers, thus resulting in a $500 cost reduction in physician fees per patient.

Video Capsule Endoscopy and Deep Enteroscopy

2017 ◽  
Author(s):  
Neil Marya ◽  
Veronica Baptista ◽  
Anupam Singh ◽  
Joseph Charpentier ◽  
David Cave
Keyword(s):  
Small Intestine ◽  
Small Bowel ◽  
Carcinoid Tumor ◽  
Capsule Endoscopy ◽  
Crohn Disease ◽  
Malignant Tumors ◽  
Video Capsule Endoscopy ◽  
X Rays ◽  
Small Bowel Tumors ◽  
Peutz Jeghers Syndrome

Until 2001, the nonsurgical evaluation of the small intestine was largely limited to the use of radiologic imaging (e.g., small bowel follow-through or enteroclysis). With the now widespread availability of video capsule endoscopy and deep enteroscopy since 2001, we are now able to visualize the length and most of the mucosa of the small intestine and manage small bowel lesions that were previously inaccessible except by surgical intervention. This review serves as an overview for these two procedures, detailing the indications and contraindications, proper timing of the procedure, technical aspects of the devices themselves, possible complications, and outcomes. Figures show endoscopic images that demonstrate multiple angioectasias, bleeding during capsule endoscopy, active Crohn disease of the small bowel, severe mucosal scalloping, small bowel carcinoid tumor, small bowel polyp associated with Peutz-Jeghers syndrome, and nonsteroidal antiinflammatory drug enteropathy; serial x-rays of a patient with a patency capsule retained inside the small intestine; a computer image showing the distribution of small bowel tumors; and a pie chart displaying the breakdown of the distribution of benign and malignant tumors that can be found in the small intestine. Videos show multiple angioectasias, bleeding during capsule endoscopy, active Crohn disease of the small bowel, small bowel carcinoid tumor, and small bowel polyp associated with Peutz-Jeghers syndrome. This review contains 10 highly rendered figures, 5 videos, and 50 references.

Wireless Video-Capsule Endoscopy Is a More Sensitive Investigative Method Than Gastro-Intestinal Endoscopy and Biopsies for the Diagnosis of Acute GI-Gvhd.

Blood ◽  
2008 ◽  
Vol 112 (11) ◽  
pp. 1123-1123
Author(s):  
Jean-Baptiste Micol ◽  
Valerie Coiteux ◽  
Laurent Pascal ◽  
Louis Terriou ◽  
Christophe Willekens ◽  
...  
Keyword(s):  
Capsule Endoscopy ◽  
Positive Impact ◽  
Specific Treatment ◽  
Final Diagnosis ◽  
Response To Therapy ◽  
Video Capsule Endoscopy ◽  
High Morbidity ◽  
Gi Tract ◽  
Wireless Video ◽  
Post Transplant

Abstract Acute gastro-intestinal graft-versus-host disease (GI-GVHD) is a major complication following allogeneic stem cell transplantation (allo-SCT) and results in high morbidity and mortality. Diagnosis of GI-GVHD is problematic due a lack of specific symptoms and confounding variables in allo-SCT patients. Although diarrhea is the most common (but non-specific) presenting symptom in acute GI-GVHD, diagnosis is especially difficult when the diarrheal disorder is atypical (i.e. when there is no or limited skin involvement). In a previous study, we reported the positive impact of wireless video-capsule endoscopy (VCE) in the diagnosis of post-transplant diarrhea. Here, we report our experience over the last 5 years with an overall diagnostic approach (including VCE) to the management of allo-SCT patients with suspected acute GI-GVHD. In addition to wireless VCE, patients with atypical post-transplant diarrhea underwent bacterial and viral investigations and upper and/or lower GI-tract endoscopy (plus biopsies, as appropriate). VCE images were scored according to standard endoscopic classification. The final diagnosis took account of the results of the investigation as a whole and the response to therapy. Between August 2002 and October 2007, 240 patients underwent allo-SCT. Thirty patients underwent 37 extensive investigations, with VCE being performed in the following situations: febrile and/or hemorrhagic diarrhea (n=17), isolated diarrhea (n=15), persistent diarrhea or relapse despite appropriate adjustment of immunosuppressive (IS) treatment (n=5). Median time between allo-SCT and VCE was 50 days (range: 19–197). The final diagnosis was acute GVHD (n=19), viral infection (n=6, with 5 CMVs and 1 HHV6s) and a combination of both in 3 cases. The result of our approach was negative in 9 cases (with a normal GI tract by VCE in 8 of them) who were ultimately diagnosed as having functional diarrhea and recovered without any specific treatment. We observed 5 (14%) VCE failures, either due to an absence of intestinal passage (n=3) or major GI hemorrhage (n=2). In the other cases, VCE results were concordant with the final diagnosis. It was noteworthy that VCE was superior to biopsies in some cases. Thus, while VCE demonstrated typical GI-GVHD lesions in 8 patients with histological proven GI-GVHD, VCE showed a normal GI tract (n=4) or GI-GVHD features in 8 other cases where the biopsies were uncertain (n=7) or non-contributive (n=1). The response to appropriate treatment was favorable in 20 cases but was unfavorable and required further therapeutic adjustment in 8 cases (7 GVHDs, 1 CMV). Five patients died of GVHD (n=3), HHV6 infection (n=1) or both (n=1). This study confirms that VCE is a more sensitive investigative method than GI-endoscopy and biopsies. This approach enhanced our ability to modulate IS treatments in patients suffering from atypical post-transplant diarrhea. With its apparently high predictive value, routine use of VCE could be of great interest, particularly with a view to avoiding unnecessary digestive biopsies.

Behçet’s disease: clinical value of the video capsule endoscopy for small intestine examination

2008 ◽  
Vol 29 (5) ◽  
pp. 601-603 ◽  
Author(s):  
Fabricio Souza Neves ◽  
Sônia Nádia Fylyk ◽  
Lais Verderame Lage ◽  
Shinichi Ishioka ◽  
Claudia Goldenstein-Schainberg ◽  
...  
Keyword(s):  
Small Intestine ◽  
Behçet’S Disease ◽  
Capsule Endoscopy ◽  
Behcet’S Disease ◽  
Behçet's Disease ◽  
Video Capsule Endoscopy ◽  
Clinical Value ◽  
Behcet's Disease

(047) Contribution of video capsule endoscopy in the diagnosis of small intestine unusual lesions

2009 ◽  
Vol 10 (2) ◽  
pp. AB26
Author(s):  
I. Serraj ◽  
L. Amrani ◽  
I. Atitar ◽  
W. Khannoussi ◽  
N. Amrani
Keyword(s):  
Small Intestine ◽  
Capsule Endoscopy ◽  
Video Capsule Endoscopy

scholarly journals Helminths detection with video capsule endoscopy

2019 ◽  
Vol 91 (11) ◽  
pp. 72-74
Author(s):  
A O Akopova ◽  
O M Mikcheeva ◽  
P L Shcherbakov ◽  
A I Parfenov
Keyword(s):  
Small Intestine ◽  
Clinical Practice ◽  
Capsule Endoscopy ◽  
High Efficiency ◽  
Inflammatory Diseases ◽  
Video Capsule Endoscopy ◽  
Unknown Etiology ◽  
Parasitic Diseases ◽  
Clinical Observations ◽  
Laboratory Techniques

The article describes clinical observations of helminthiasis detection in 18 of 208 patients during video capsule endoscopy (VCE). Indications for the appointment of VCE were complex clinical situations associated with the search for inflammatory diseases of the small intestine and sources of small intestine bleeding. Because of the high cost of VCE the diagnosis of parasitic diseases should be based on laboratory techniques in clinical practice. Only in case of anemia of unknown etiology VCE demonstrates high efficiency.

Video Capsule Endoscopy and Deep Enteroscopy

2015 ◽  
Author(s):  
Neil Marya ◽  
Veronica Baptista ◽  
Anupam Singh ◽  
Joseph Charpentier ◽  
David Cave
Keyword(s):  
Small Intestine ◽  
Small Bowel ◽  
Carcinoid Tumor ◽  
Capsule Endoscopy ◽  
Crohn Disease ◽  
Malignant Tumors ◽  
Video Capsule Endoscopy ◽  
X Rays ◽  
Small Bowel Tumors ◽  
Peutz Jeghers Syndrome

Until 2001, the nonsurgical evaluation of the small intestine was largely limited to the use of radiologic imaging (e.g., small bowel follow-through or enteroclysis). With the now widespread availability of video capsule endoscopy and deep enteroscopy since 2001, we are now able to visualize the length and most of the mucosa of the small intestine and manage small bowel lesions that were previously inaccessible except by surgical intervention. This review serves as an overview for these two procedures, detailing the indications and contraindications, proper timing of the procedure, technical aspects of the devices themselves, possible complications, and outcomes. Figures show endoscopic images that demonstrate multiple angioectasias, bleeding during capsule endoscopy, active Crohn disease of the small bowel, severe mucosal scalloping, small bowel carcinoid tumor, small bowel polyp associated with Peutz-Jeghers syndrome, and nonsteroidal antiinflammatory drug enteropathy; serial x-rays of a patient with a patency capsule retained inside the small intestine; a computer image showing the distribution of small bowel tumors; and a pie chart displaying the breakdown of the distribution of benign and malignant tumors that can be found in the small intestine. Videos show multiple angioectasias, bleeding during capsule endoscopy, active Crohn disease of the small bowel, small bowel carcinoid tumor, and small bowel polyp associated with Peutz-Jeghers syndrome. This review contains 10 highly rendered figures, 5 videos, and 50 references.

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