Parametric Analysis of Eustachian Tube Function Using Fully Coupled Fluid-Structure Interaction Models

Author(s):  
Francis J. Sheer ◽  
Samir N. Ghadiali

Otitis Media (OM) is the most commonly diagnosed childhood illness and has health care related cost of four billion dollars annually. [1] The onset of OM has been directly related to Eustachian Tube (ET) dysfunction. The ET has three main physiological functions, and when these functions are compromised, middle ear (ME) disorders arise. It is also known that specific populations of patients, such as those with cranio-facial abnormalities, such as a cleft palate, have a 100% onset rate of OM. Even though ET dysfunction has been related to OM, the underlying reasons for ET dysfunction in certain populations remains unknown. To gain an understanding of this system, we use fully coupled fluid-structure interaction (FSI) models of the ET based on geometries reconstructed from histological images. Using these models in systematic parameter variation studies allows us to identify which parameters of the ET can cause dysfunction. Using healthy adult subjects as a model for a well-functioning ET, we determined ET function to be sensitive to changes in TVP muscle force.

2018 ◽  
Vol 21 (16) ◽  
pp. 813-823 ◽  
Author(s):  
John T. Wilson ◽  
Lowell T. Edgar ◽  
Saurabh Prabhakar ◽  
Marc Horner ◽  
Raoul van Loon ◽  
...  

Author(s):  
Fande Kong ◽  
Xiao-Chuan Cai

Fluid-structure interaction (FSI) problems are computationally very challenging. In this paper we consider the monolithic approach for solving the fully coupled FSI problem. Most existing techniques, such as multigrid methods, do not work well for the coupled system since the system consists of elliptic, parabolic and hyperbolic components all together. Other approaches based on direct solvers do not scale to large numbers of processors. In this paper, we introduce a multilevel unstructured mesh Schwarz preconditioned Newton–Krylov method for the implicitly discretized, fully coupled system of partial differential equations consisting of incompressible Navier–Stokes equations for the fluid flows and the linear elasticity equation for the structure. Several meshes are required to make the solution algorithm scalable. This includes a fine mesh to guarantee the solution accuracy, and a few isogeometric coarse meshes to speed up the convergence. Special attention is paid when constructing and partitioning the preconditioning meshes so that the communication cost is minimized when the number of processor cores is large. We show numerically that the proposed algorithm is highly scalable in terms of the number of iterations and the total compute time on a supercomputer with more than 10,000 processor cores for monolithically coupled three-dimensional FSI problems with hundreds of millions of unknowns.


Author(s):  
Francis J. Sheer ◽  
Samir N. Ghadiali

The Eustachian Tube (ET) is a collapsible tube that connects the Middle Ear (ME) to the nasopharynx (NP). The ET is responsible for three primary functions: 1) regulation of ME pressure 2) protection of the ME from foreign pathogens and 3) drainage of fluid from the ME. [1] In healthy patients, the ET opens during swallowing because the surrounding tissue is deformed by muscle activity. If the ET fails to open, the ME develops painful sub-ambient pressure and fluid accumulates in the ME. ET dysfunction results in Otitis Media (OM), the most common ME disorder in children. The overall goal of our lab is to identify the mechanisms responsible for ET dysfunction and to develop novel treatments for OM that target the ET.


2014 ◽  
Vol 980 ◽  
pp. 102-106
Author(s):  
N.I. Ismail ◽  
A.H. Zulkifli ◽  
Mohd Zulkifly Abdullah ◽  
M. Hisyam Basri ◽  
M.M. Mahadzir

Twist Morphing (TM) wing is one of biomimetic MAV design that highly depends on morphing force actuation. Despite of vital morphing force influenced, the effect of morphing force variation on the aerodynamic performances of TM wing was not fully comprehended due to high complexity of fluid-structure interaction (FSI) behaviour. To elucidate the effect of morphing force influence, a series of TM wing with different morphing force intensity was used here to elucidate the effect of morphing force on CL,CD, and CMdistribution. Fully coupled Ansys-FSI method was employed in this study. CLand CMresults showed that TM wing with higher morphing force configuration had induced better static stability and higher CLdistribution. However, TM wing also promoted earlier AOAstallincidence and higher CDpenalty than the baseline wings. These situations turn out to be greater in the TM wing cases with higher morphing force configurations.


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