Polarization-based skin cancer detection in vivo

2021 ◽  
Author(s):  
Lioudmila Tchvialeva ◽  
Daniel C. Louie ◽  
Yuheng Wang ◽  
Sunil Kalia ◽  
Harvey Lui ◽  
...  
2009 ◽  
Vol 02 (03) ◽  
pp. 289-294 ◽  
Author(s):  
MILOŠ TODOROVIĆ ◽  
SHULIANG JIAO ◽  
GEORGE STOICA ◽  
LIHONG V. WANG

We report on the use of a fiber-based Mueller-matrix optical coherence tomography (OCT) system with continuous source-polarization modulation for in vivo imaging of early stages of skin cancer in SENCAR mice. A homemade hand-held probe with integrated optical scanning and beam delivering optics was coupled in the sample arm. The OCT images show the morphological changes in skin resulting from pre-cancerous papilloma formations that are consistent with histology, thus demonstrating the system's potential for early skin cancer detection.


Electronics ◽  
2020 ◽  
Vol 9 (9) ◽  
pp. 1503 ◽  
Author(s):  
Emanuele Torti ◽  
Raquel Leon ◽  
Marco La Salvia ◽  
Giordana Florimbi ◽  
Beatriz Martinez-Vega ◽  
...  

The early detection of skin cancer is of crucial importance to plan an effective therapy to treat the lesion. In routine medical practice, the diagnosis is based on the visual inspection of the lesion and it relies on the dermatologists’ expertise. After a first examination, the dermatologist may require a biopsy to confirm if the lesion is malignant or not. This methodology suffers from false positives and negatives issues, leading to unnecessary surgical procedures. Hyperspectral imaging is gaining relevance in this medical field since it is a non-invasive and non-ionizing technique, capable of providing higher accuracy than traditional imaging methods. Therefore, the development of an automatic classification system based on hyperspectral images could improve the medical practice to distinguish pigmented skin lesions from malignant, benign, and atypical lesions. Additionally, the system can assist general practitioners in first aid care to prevent noncritical lesions from reaching dermatologists, thereby alleviating the workload of medical specialists. In this paper is presented a parallel pipeline for skin cancer detection that exploits hyperspectral imaging. The computational times of the serial processing have been reduced by adopting multicore and many-core technologies, such as OpenMP and CUDA paradigms. Different parallel approaches have been combined, leading to the development of fifteen classification pipeline versions. Experimental results using in-vivo hyperspectral images show that a hybrid parallel approach is capable of classifying an image of 50 × 50 pixels with 125 bands in less than 1 s.


2021 ◽  
Vol 26 (03) ◽  
Author(s):  
Daniel C. Louie ◽  
Lioudmila Tchvialeva ◽  
Sunil Kalia ◽  
Harvey Lui ◽  
Tim K. Lee

2021 ◽  
Vol 140 ◽  
pp. 107006
Author(s):  
Yuheng Wang ◽  
Daniel C. Louie ◽  
Jiayue Cai ◽  
Lioudmila Tchvialeva ◽  
Harvey Lui ◽  
...  

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