Functional magnetic resonance imaging of the rat cerebellum during electrical stimulation of the fore- and hindpaw at 7 T

1999 ◽  
Author(s):  
Ronald Peeters ◽  
Marleen Verhoye ◽  
Bart Vos ◽  
Erik De Schutter ◽  
Anne-Marie Van der Linden
Keyword(s):  
Magnetic Resonance Imaging ◽  
Electrical Stimulation ◽  
Magnetic Resonance ◽  
Functional Magnetic Resonance Imaging ◽  
Functional Magnetic Resonance ◽  
Resonance Imaging ◽  
Rat Cerebellum ◽  
Stimulation Of

Reduced visual evoked responses in multiple sclerosis patients with optic neuritis: Comparison of functional magnetic resonance imaging and visual evoked potentials

1999 ◽  
Vol 5 (3) ◽  
pp. 161-164 ◽  
Author(s):  
P J Gareau ◽  
J S Gati ◽  
R S Menon ◽  
D Lee ◽  
G Rice ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Multiple Sclerosis ◽  
Magnetic Resonance ◽  
Functional Magnetic Resonance Imaging ◽  
Optic Neuritis ◽  
Functional Magnetic Resonance ◽  
Resonance Imaging ◽  
Multiple Sclerosis Patients ◽  
Stimulation Of ◽  
Visual Evoked

The limited application of functional magnetic resonance imaging (fMRI) for investigations of multiple sclerosis (MS) patients has already shown that deficits of the motor, cognitive and visual systems may be identified by differences in the patterns of activation in response to a suitable stimulus. In MS patients with unilateral optic neuritis, the area of activation in the primary visual cortex, measured by fMRI techniques, is dramatically reduced in response to stimulation of the affected eye. The latency of the major positive component of the visual evoked potential (VEP) recorded upon stimulation of the affected eye is significantly increased in these patients, as compared to the unaffected eye and normal volunteers. We have found a correlation between the neural response measured using fMRI and the latency of the VEP. fMRI signal responses have the potential to provide more detailed topographic information relating to functional deficits in MS.

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