SU-E-T-278: Risk of Developing a Second Cancer in the Breast for Hodgkin Lymphoma Patients Receiving Carbon Ion Therapy Versus Proton Therapy

Carbon ion therapy is a type of radiotherapies that can deliver high-dose radiation to a tumor while minimizing the dose delivered to the organs at risk; this profile differs from that of photon radiotherapy. Moreover, carbon ions are classified as high-linear energy transfer radiation and are expected to be effective for even photon-resistant tumors. Recently, high-precision radiotherapy modalities such as stereotactic body radiotherapy (SBRT), proton therapy, and carbon ion therapy have been used for patients with early-stage non-small-cell lung cancer, and the results are promising, as, for carbon ion therapy, local control and overall survival rates at 5 years are 80–90% and 40–50%, respectively. Carbon ion therapy may be theoretically superior to SBRT and proton therapy, but the literature that is currently available does not show a statistically significant difference among these treatments. Carbon ion therapy demonstrates a better dose distribution than both SBRT and proton therapy in most cases of early-stage lung cancer. Therefore, carbon ion therapy may be safer for treating patients with adverse conditions such as large tumors, central tumors, and poor pulmonary function. Furthermore, carbon ion therapy may also be suitable for dose escalation and hypofractionation.

Download Full-text

Comparison of photon volumetric modulated arc therapy, intensity-modulated proton therapy, and intensity-modulated carbon ion therapy for delivery of hypo-fractionated thoracic radiotherapy

Radiation Oncology ◽

10.1186/s13014-017-0866-0 ◽

2017 ◽

Vol 12 (1) ◽

Cited By ~ 3

Author(s):

Alexander Chi ◽

Lien-Chun Lin ◽

Sijin Wen ◽

Haijuan Yan ◽

Wen-Chien Hsi

Keyword(s):

Proton Therapy ◽

Volumetric Modulated Arc Therapy ◽

Thoracic Radiotherapy ◽

Carbon Ion Therapy ◽

Carbon Ion ◽

Intensity Modulated Proton Therapy ◽

Intensity Modulated ◽

Arc Therapy ◽

Ion Therapy

Download Full-text

Synchrotrons for Hadrontherapy

Reviews of Accelerator Science and Technology ◽

10.1142/s1793626809000284 ◽

2009 ◽

Vol 02 (01) ◽

pp. 157-178 ◽

Cited By ~ 1

Author(s):

Marco G. Pullia

Keyword(s):

Proton Therapy ◽

Medical Community ◽

Carbon Ions ◽

Carbon Ion Therapy ◽

Carbon Ion ◽

Ion Therapy ◽

Therapy Center

Since 1990, when the world's first hospital-based proton therapy center opened in Loma Linda, California, interest in dedicated proton and carbon ion therapy facilities has been growing steadily. Today, many proton therapy centers are in operation, but the number of centers offering carbon ion therapy is still very low. This difference reflects the fact that protons are well accepted by the medical community, whereas radiotherapy with carbon ions is still experimental. Furthermore, accelerators for carbon ions are larger, more complicated and more expensive than those for protons only. This article describes the accelerator performance required for hadrontherapy and how this is realized, with particular emphasis on carbon ion synchrotrons.

Download Full-text