Correction to “Meeting the Challenge of Predicting Hepatic Clearance of Compounds Slowly Metabolized by Cytochrome P450 Using a Novel Hepatocyte Model, HepatoPac”

2013 ◽  
Vol 42 (1) ◽  
pp. 200-200
Keyword(s):  
Cytochrome P450 ◽  
Hepatic Clearance

scholarly journals Profiling of hepatic clearance pathways of Pittsburgh compound B and human liver cytochrome p450 phenotyping

2013 ◽  
Vol 3 (1) ◽  
pp. 10 ◽  
Author(s):  
Anne Van Vlaslaer ◽  
Russell J Mortishire-Smith ◽  
Claire Mackie ◽  
Xavier Langlois ◽  
Mark E Schmidt
Keyword(s):  
Cytochrome P450 ◽  
Human Liver ◽  
Hepatic Clearance ◽  
Pittsburgh Compound B ◽  
Liver Cytochrome

Meeting the Challenge of Predicting Hepatic Clearance of Compounds Slowly Metabolized by Cytochrome P450 Using a Novel Hepatocyte Model, HepatoPac

2013 ◽  
Vol 41 (12) ◽  
pp. 2024-2032 ◽  
Author(s):  
Tom S. Chan ◽  
Hongbin Yu ◽  
Amanda Moore ◽  
Salman R. Khetani ◽  
Donald Tweedie
Keyword(s):  
Cytochrome P450 ◽  
Hepatic Clearance

Molecular evolution of a cytochrome P450 for the synthesis of potential antidepressant (2R,6R)-hydroxynorketamine

2021 ◽  
Author(s):  
Ansgar Bokel ◽  
Michael C. Hutter ◽  
Vlada B. Urlacher
Keyword(s):  
Cytochrome P450 ◽  
Molecular Evolution ◽  
Cytochrome P450 Monooxygenase ◽  
P450 Monooxygenase ◽  
Effective Synthesis

Engineered cytochrome P450 monooxygenase CYP154E1 enables the effective synthesis of the potential antidepressant (2R,6R)-hydroxynorketamine via N-demethylation and regio- and stereoselective hydroxylation of (R)-ketamine.

Comparison of mechanism-based inhibition of human cytochrome P450 2C19 by ticlopidine, clopidogrel, and prasugrel

Xenobiotica ◽  
2009 ◽  
Vol 00 (00) ◽  
pp. 090901052457079-8
Author(s):  
Y. Nishiya ◽  
K. Hagihara ◽  
A. Kurihara ◽  
N. Okudaira ◽  
N.A. Farid ◽  
...  
Keyword(s):  
Cytochrome P450 ◽  
Human Cytochrome ◽  
Cytochrome P450 2C19
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