Application of Three-Dimensional Quantitative Structure-Activity Relationships of P-Glycoprotein Inhibitors and Substrates

Structure Activity ◽

P Glycoprotein ◽

Glycoprotein Inhibitors

Three-Dimensional Quantitative Structure-Activity Relationships of Inhibitors of P-Glycoprotein

Molecular Pharmacology ◽

10.1124/mol.61.5.964 ◽

2002 ◽

Vol 61 (5) ◽

pp. 964-973 ◽

Cited By ~ 127

Author(s):

Sean Ekins ◽

Richard B. Kim ◽

Brenda F. Leake ◽

Anne H. Dantzig ◽

Erin G. Schuetz ◽

...

Keyword(s):

Three Dimensional ◽

Quantitative Structure ◽

Structure Activity ◽

P Glycoprotein ◽

Three-dimensional quantitative structure-activity relationships of pyrrolopyridinone as cell division cycle kinase inhibitors by CoMFA and CoMSIA

Journal of Molecular Modeling ◽

10.1007/s00894-011-1016-5 ◽

2011 ◽

Vol 17 (8) ◽

pp. 2113-2130 ◽

Cited By ~ 2

Author(s):

Junxia Zheng ◽

Gaokeng Xiao ◽

Jialiang Guo ◽

Longyi Rao ◽

Wei Chao ◽

...

Keyword(s):

Cell Division ◽

Kinase Inhibitors ◽

Three Dimensional ◽

Cell Division Cycle ◽

Quantitative Structure ◽

Structure Activity ◽

Biological Evaluation, Structure−Activity Relationships, and Three-Dimensional Quantitative Structure−Activity Relationship Studies of Dihydro-β-agarofuran Sesquiterpenes as Modulators of P-Glycoprotein-Dependent Multidrug Resistance

10.1021/jm070290v ◽

2007 ◽

Vol 50 (20) ◽

pp. 4808-4817 ◽

Cited By ~ 30

Author(s):

Carolina P. Reyes ◽

Francisco Muñoz-Martínez ◽

Ivan R. Torrecillas ◽

Cristina R. Mendoza ◽

Francisco Gamarro ◽

...

Keyword(s):

Multidrug Resistance ◽

Three Dimensional ◽

Quantitative Structure Activity Relationship ◽

Structure Activity Relationship ◽

Biological Evaluation ◽

Activity Relationship ◽

Quantitative Structure ◽

Structure Activity ◽

P Glycoprotein

Prediction of Cross-Recognition of Peptide-HLA A2 by Melan-A-Specific Cytotoxic T Lymphocytes Using Three-Dimensional Quantitative Structure-Activity Relationships

PLoS ONE ◽

10.1371/journal.pone.0065590 ◽

2013 ◽

Vol 8 (7) ◽

pp. e65590 ◽

Cited By ~ 3

Author(s):

Theres Fagerberg ◽

Vincent Zoete ◽

Sebastien Viatte ◽

Petra Baumgaertner ◽

Pedro M. Alves ◽

...

Keyword(s):

T Lymphocytes ◽

Cytotoxic T Lymphocytes ◽

Three Dimensional ◽

Quantitative Structure ◽

Structure Activity ◽

Three-dimensional structural databases developed for quantitative structure—activity relationships studies

Chemometrics and Intelligent Laboratory Systems ◽

10.1016/0169-7439(90)80121-l ◽

1990 ◽

Vol 8 (2) ◽

pp. 93

Keyword(s):

Three Dimensional ◽

Quantitative Structure ◽

Structure Activity ◽

Structural Databases

Three-dimensional quantitative structure-activity relationships of 5-HT receptor binding data for tetrahydropyridinylindole derivatives: a comparison of the Hansch and CoMFA methods

10.1021/jm00077a003 ◽

1993 ◽

Vol 36 (25) ◽

pp. 4006-4014 ◽

Cited By ~ 49

Author(s):

Atul Agarwal ◽

Philip P. Pearson ◽

Ethan Will Taylor ◽

Hong B. Li ◽

Torsten Dahlgren ◽

...

Keyword(s):

Receptor Binding ◽

Three Dimensional ◽

Quantitative Structure ◽

Structure Activity ◽

Binding Data ◽

Three-Dimensional Quantitative Structure−Activity Relationships from Molecular Similarity Matrices and Genetic Neural Networks. 1. Method and Validations

10.1021/jm970487v ◽

1997 ◽

Vol 40 (26) ◽

pp. 4347-4359 ◽

Cited By ~ 96

Author(s):

Sung-Sau So ◽

Martin Karplus

Keyword(s):

Neural Networks ◽

Molecular Similarity ◽

Three Dimensional ◽

Quantitative Structure ◽

Structure Activity ◽

Similarity Matrices

Three-Dimensional Quantitative Structure−Activity Relationships from Molecular Similarity Matrices and Genetic Neural Networks. 2. Applications

10.1021/jm970488n ◽

1997 ◽

Vol 40 (26) ◽

pp. 4360-4371 ◽

Cited By ~ 52

Author(s):

Sung-Sau So ◽

Martin Karplus

Keyword(s):

Neural Networks ◽

Molecular Similarity ◽

Three Dimensional ◽

Quantitative Structure ◽

Structure Activity ◽

Similarity Matrices

Computational identification of RNA functional determinants by three-dimensional quantitative structure–activity relationships

Nucleic Acids Research ◽

10.1093/nar/gku816 ◽

2014 ◽

Vol 42 (17) ◽

pp. 11261-11271 ◽

Cited By ~ 4

Author(s):

Marc-Frédérick Blanchet ◽

Karine St-Onge ◽

Véronique Lisi ◽

Julie Robitaille ◽

Sylvie Hamel ◽

...

Keyword(s):

Three Dimensional ◽

Quantitative Structure ◽

Structure Activity ◽

Computational Identification ◽

ChemInform Abstract: Atomic Physicochemical Parameters for Three Dimensional Structure Directed Quantitative Structure-Activity Relationships. Part 4. Additional Parameters for Hydrophobic and Dispersive Interactions and Their Application for an Automated

ChemInform ◽

10.1002/chin.198950038 ◽

1989 ◽

Vol 20 (50) ◽

Author(s):

V. N. VISWANADHAN ◽

A. K. GHOSE ◽

G. R. REVANKAR ◽

R. K. ROBINS

Keyword(s):

Physicochemical Parameters ◽

Three Dimensional ◽

Dimensional Structure ◽

Quantitative Structure ◽

Three Dimensional Structure ◽

Structure Activity ◽