Cystic fibrosis transmembrane conductance regulator: nucleotide binding to a synthetic peptide

Science ◽

10.1126/science.1703660 ◽

1991 ◽

Vol 251 (4993) ◽

pp. 555-557 ◽

Author(s):

P. Thomas ◽

P. Shenbagamurthi ◽

X. Ysern ◽

P. Pedersen

Keyword(s):

Cystic Fibrosis ◽

Synthetic Peptide ◽

Nucleotide Binding ◽

Transmembrane Conductance Regulator ◽

Transmembrane Conductance ◽

Cystic Fibrosis Transmembrane

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The cystic fibrosis transmembrane conductance regulator. Nucleotide binding to a synthetic peptide segment from the second predicted nucleotide binding fold.

Journal of Biological Chemistry ◽

10.1016/s0021-9258(17)36663-2 ◽

1994 ◽

Vol 269 (20) ◽

pp. 14584-14588

Author(s):

Y.H. Ko ◽

P.J. Thomas ◽

P.L. Pedersen

Keyword(s):

Cystic Fibrosis ◽

Synthetic Peptide ◽

Nucleotide Binding ◽

Transmembrane Conductance Regulator ◽

Transmembrane Conductance ◽

Cystic Fibrosis Transmembrane

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Antibody against a cystic fibrosis transmembrane conductance regulator-derived synthetic peptide inhibits anion currents in human colonic cell line T84.

Journal of Biological Chemistry ◽

10.1016/s0021-9258(18)42460-x ◽

1992 ◽

Vol 267 (12) ◽

pp. 8411-8416 ◽

Author(s):

H.C. Chan ◽

M.A. Kaetzel ◽

D.J. Nelson ◽

P Hazarika ◽

J.R. Dedman

Keyword(s):

Cystic Fibrosis ◽

Cell Line ◽

Synthetic Peptide ◽

Transmembrane Conductance Regulator ◽

Transmembrane Conductance ◽

Cystic Fibrosis Transmembrane

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The cystic fibrosis transmembrane conductance regulator. Effects of the most common cystic fibrosis-causing mutation on the secondary structure and stability of a synthetic peptide.

Journal of Biological Chemistry ◽

10.1016/s0021-9258(18)42610-5 ◽

1992 ◽

Vol 267 (9) ◽

pp. 5727-5730

Author(s):

P.J. Thomas ◽

P Shenbagamurthi ◽

J Sondek ◽

J.M. Hullihen ◽

P.L. Pedersen

Keyword(s):

Cystic Fibrosis ◽

Secondary Structure ◽

Synthetic Peptide ◽

Transmembrane Conductance Regulator ◽

Transmembrane Conductance ◽

Structure And Stability ◽

Cystic Fibrosis Transmembrane

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A recombinant polypeptide model of the second nucleotide-binding fold of the cystic fibrosis transmembrane conductance regulator functions as an active ATPase, GTPase and adenylate kinase

FEBS Letters ◽

10.1016/s0014-5793(97)00574-7 ◽

1997 ◽

Vol 410 (2-3) ◽

pp. 180-186 ◽

Author(s):

Christoph Randak ◽

Peter Neth ◽

Ennes A Auerswald ◽

Christoph Eckerskorn ◽

Irmgard Assfalg-Machleidt ◽

...

Keyword(s):

Cystic Fibrosis ◽

Adenylate Kinase ◽

Nucleotide Binding ◽

Transmembrane Conductance Regulator ◽

Transmembrane Conductance ◽

Recombinant Polypeptide ◽

Cystic Fibrosis Transmembrane

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Nucleotide-binding domains of human cystic fibrosis transmembrane conductance regulator: detailed sequence analysis and three-dimensional modeling of the heterodimer

Cellular and Molecular Life Sciences ◽

10.1007/s00018-003-3386-z ◽

2004 ◽

Vol 61 (2) ◽

pp. 230-242 ◽

Author(s):

I. Callebaut ◽

R. Eudes ◽

J.-P. Mornon ◽

P. Lehn

Keyword(s):

Cystic Fibrosis ◽

Sequence Analysis ◽

Three Dimensional ◽

Nucleotide Binding ◽

Transmembrane Conductance Regulator ◽

Transmembrane Conductance ◽

Three Dimensional Modeling ◽

Binding Domains ◽

Dimensional Modeling ◽

Cystic Fibrosis Transmembrane

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Impact of the ΔF508 Mutation in First Nucleotide-binding Domain of Human Cystic Fibrosis Transmembrane Conductance Regulator on Domain Folding and Structure

Journal of Biological Chemistry ◽

10.1074/jbc.m410968200 ◽

2004 ◽

Vol 280 (2) ◽

pp. 1346-1353 ◽

Author(s):

Hal A. Lewis ◽

Xun Zhao ◽

Chi Wang ◽

J. Michael Sauder ◽

Isabelle Rooney ◽

...

Keyword(s):

Cystic Fibrosis ◽

Nucleotide Binding ◽

Binding Domain ◽

Transmembrane Conductance Regulator ◽

Nucleotide Binding Domain ◽

Transmembrane Conductance ◽

Cystic Fibrosis Transmembrane

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The first-nucleotide binding domain of the cystic-fibrosis transmembrane conductance regulator is important for inhibition of the epithelial Na+ channel

Proceedings of the National Academy of Sciences ◽

10.1073/pnas.96.9.5310 ◽

1999 ◽

Vol 96 (9) ◽

pp. 5310-5315 ◽

Author(s):

R. Schreiber ◽

A. Hopf ◽

M. Mall ◽

R. Greger ◽

K. Kunzelmann

Keyword(s):

Cystic Fibrosis ◽

Nucleotide Binding ◽

Binding Domain ◽

Transmembrane Conductance Regulator ◽

Nucleotide Binding Domain ◽

Transmembrane Conductance ◽

Cystic Fibrosis Transmembrane ◽

Epithelial Na Channel

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Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) Nucleotide-Binding Domain 1 (NBD-1) and CFTR Truncated within NBD-1 Target to the Epithelial Plasma Membrane and Increase Anion Permeability†

Biochemistry ◽

10.1021/bi980436f ◽

1998 ◽

Vol 37 (43) ◽

pp. 15222-15230 ◽

Author(s):

J. P. Clancy ◽

J. S. Hong ◽

Z. Bebök ◽

S. A. King ◽

S. Demolombe ◽

...

Keyword(s):

Cystic Fibrosis ◽

Plasma Membrane ◽

Nucleotide Binding ◽

Binding Domain ◽

Transmembrane Conductance Regulator ◽

Nucleotide Binding Domain ◽

Transmembrane Conductance ◽

Anion Permeability ◽

Cystic Fibrosis Transmembrane ◽

Nucleotide Binding Domain 1

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The Two Nucleotide-binding Domains of Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) Have Distinct Functions in Controlling Channel Activity

Journal of Biological Chemistry ◽

10.1074/jbc.270.4.1711 ◽

1995 ◽

Vol 270 (4) ◽

pp. 1711-1717 ◽

Author(s):

Mark R. Carson ◽

Sue M. Travis ◽

Michael J. Welsh

Keyword(s):

Cystic Fibrosis ◽

Nucleotide Binding ◽

Transmembrane Conductance Regulator ◽

Channel Activity ◽

Transmembrane Conductance ◽

Binding Domains ◽

Cystic Fibrosis Transmembrane

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The Nucleotide Binding Folds of the Cystic Fibrosis Transmembrane Conductance Regulator Are Extracellularly Accessible†

Biochemistry ◽

10.1021/bi9701585 ◽

1997 ◽

Vol 36 (25) ◽

pp. 7739-7745 ◽

Author(s):

Darren B. Gruis ◽

Elmer M. Price

Keyword(s):

Cystic Fibrosis ◽

Nucleotide Binding ◽

Transmembrane Conductance Regulator ◽

Transmembrane Conductance ◽

Cystic Fibrosis Transmembrane

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