scholarly journals Global Annotation, Expression Analysis, and Stability of Candidate sRNAs in Group B Streptococcus

mBio ◽  
2021 ◽  
Author(s):  
Rebecca A. Keogh ◽  
Brady L. Spencer ◽  
Hailee M. Sorensen ◽  
Rachel L. Zapf ◽  
Paul Briaud ◽  
...  
Keyword(s):  
Stress Response ◽  
Expression Analysis ◽  
In Silico ◽  
Group B Streptococcus ◽  
Virulence Regulation ◽  
Sequencing Technologies ◽  
Streptococcal Species ◽  
Group B

In recent years, sRNAs have emerged as potent regulatory molecules in bacteria, including numerous streptococcal species, and contribute to diverse processes, including stress response, metabolism, housekeeping, and virulence regulation. Improvements in sequencing technologies and in silico analyses have facilitated identification of these regulatory molecules as well as improved attempts to determine the location of sRNA genes on the genome.

scholarly journals A composite transposon associated with erythromycin and clindamycin resistance in group B Streptococcus

2007 ◽  
Vol 56 (7) ◽  
pp. 947-955 ◽  
Author(s):  
Karen M. Puopolo ◽  
David C. Klinzing ◽  
Michelle P. Lin ◽  
Derek L. Yesucevitz ◽  
Michael J. Cieslewicz
Keyword(s):  
Genetic Basis ◽  
Southern Hybridization ◽  
Rapd Analysis ◽  
Random Amplified Polymorphic Dna ◽  
Group B Streptococcus ◽  
Macrolide Resistance ◽  
Chromosomal Site ◽  
Streptococcal Species ◽  
Group B ◽  
Us Cities

Group B Streptococcus (GBS) resistant to erythromycin and clindamycin has been isolated with increasing frequency since the mid-1990s. This work studied GBS isolates from three US cities to determine the genetic basis of the macrolide resistance phenotype. ermB genes were amplified from five isolates collected in Boston, Pittsburgh and Seattle from infant and adult sources. Gene-walking methods were used to determine the chromosomal location of ermB and to identify associated genes. Southern mapping and random amplified polymorphic DNA (RAPD) analyses were used to distinguish the isolates. The ermB gene was present on the chromosome within a composite Tn917/Tn916-like transposon similar to one identified in Streptococcus pneumoniae. Four strains from Boston and Pittsburgh were serotype V and identical by Southern hybridization and RAPD analysis. The Seattle isolate was serotype Ib, with different patterns on RAPD analysis and Southern mapping. The composite transposon was integrated at an identical chromosomal site in all five isolates. The presence of this composite transposon in both GBS and pneumococci suggests that ermB-mediated macrolide resistance in streptococci may be due to the horizontal transfer of a mobile transposable element, and raises concern for further dissemination of high-grade erythromycin and clindamycin resistance among streptococcal species.

scholarly journals Lack of diagnostic-escape mutants of group B streptococcus in Slovenia

2021 ◽  
Author(s):  
Tina Perme ◽  
Daniel Golparian ◽  
Magnus Unemo ◽  
Samo Jeverica
Keyword(s):  
Group B Streptococcus ◽  
Escape Mutants ◽  
Group B

Pyomyositis as a manifestation of late‐onset group B Streptococcus disease

2021 ◽  
Author(s):  
Akihiko Shimizu ◽  
Mariko Shimizu ◽  
Shigeru Nomura ◽  
Yoshiyuki Yamada
Keyword(s):  
Late Onset ◽  
Group B Streptococcus ◽  
Group B ◽  
Onset Group
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