Analysis of Glycosyl-Enzyme Intermediate Formation in the Catalytic Mechanism of Influenza Virus Neuraminidase Using Molecular Modeling

2020 ◽  
Vol 85 (4) ◽  
pp. 490-498
Author(s):  
E. M. Kirilin ◽  
V. K. Švedas
Keyword(s):  
Influenza Virus ◽  
Molecular Modeling ◽  
Catalytic Mechanism ◽  
Intermediate Formation ◽  
Influenza Virus Neuraminidase ◽  
Enzyme Intermediate

Structure of Influenza Virus Neuraminidase B/Lee/40 Complexed with Sialic Acid and a Dehydro Analog at 1.8-.ANG. Resolution: Implications for the Catalytic Mechanism

Biochemistry ◽  
1994 ◽  
Vol 33 (27) ◽  
pp. 8172-8179 ◽  
Author(s):  
Musiri N. Janakiraman ◽  
Clinton L. White ◽  
W. Graeme Laver ◽  
Gillian M. Air ◽  
Ming Luo
Keyword(s):  
Influenza Virus ◽  
Sialic Acid ◽  
Catalytic Mechanism ◽  
Influenza Virus Neuraminidase

Docking and 3D QSAR study of thiourea analogs as potent inhibitors of influenza virus neuraminidase

2010 ◽  
Vol 16 (12) ◽  
pp. 1809-1818 ◽  
Author(s):  
Jiaying Sun ◽  
Shaoxi Cai ◽  
Hu Mei ◽  
Jian Li ◽  
Ning Yan ◽  
...  
Keyword(s):  
Influenza Virus ◽  
3D Qsar ◽  
Qsar Study ◽  
Influenza Virus Neuraminidase

Influenza Virus Neuraminidase Inhibitory Activity of Phlorotannins from the Edible Brown AlgaEcklonia cava

2011 ◽  
Vol 59 (12) ◽  
pp. 6467-6473 ◽  
Author(s):  
Young Bae Ryu ◽  
Hyung Jae Jeong ◽  
So Young Yoon ◽  
Ji-Young Park ◽  
Young Min Kim ◽  
...  
Keyword(s):  
Influenza Virus ◽  
Inhibitory Activity ◽  
Influenza Virus Neuraminidase

Difluorosialic acids, potent novel influenza virus neuraminidase inhibitors, induce fewer drug resistance-associated neuraminidase mutations than does oseltamivir

2015 ◽  
Vol 210 ◽  
pp. 126-132 ◽  
Author(s):  
S.-H. Sheldon Tai ◽  
Olga Agafitei ◽  
Zhizeng Gao ◽  
Richard Liggins ◽  
Martin Petric ◽  
...  
Keyword(s):  
Drug Resistance ◽  
Influenza Virus ◽  
Neuraminidase Inhibitors ◽  
Influenza Virus Neuraminidase

scholarly journals Induced opening of influenza virus neuraminidase N2 150-loop suggests an important role in inhibitor binding

2013 ◽  
Vol 3 (1) ◽  
Author(s):  
Yan Wu ◽  
Guangrong Qin ◽  
Feng Gao ◽  
Yue Liu ◽  
Christopher J. Vavricka ◽  
...  
Keyword(s):  
Influenza Virus ◽  
Inhibitor Binding ◽  
Influenza Virus Neuraminidase
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